| Full name: zinc finger protein 646 | Alias Symbol: KIAA0296 | ||
| Type: protein-coding gene | Cytoband: 16p11.2 | ||
| Entrez ID: 9726 | HGNC ID: HGNC:29004 | Ensembl Gene: ENSG00000167395 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF646:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF646 | 9726 | 204876_at | 0.0817 | 0.7334 | |
| GSE20347 | ZNF646 | 9726 | 204876_at | -0.0351 | 0.6874 | |
| GSE23400 | ZNF646 | 9726 | 204876_at | -0.0748 | 0.0446 | |
| GSE26886 | ZNF646 | 9726 | 204876_at | 0.3331 | 0.0264 | |
| GSE29001 | ZNF646 | 9726 | 204876_at | -0.2599 | 0.0477 | |
| GSE38129 | ZNF646 | 9726 | 204876_at | -0.1177 | 0.2892 | |
| GSE45670 | ZNF646 | 9726 | 204876_at | -0.0419 | 0.6397 | |
| GSE53622 | ZNF646 | 9726 | 53715 | 0.1640 | 0.0078 | |
| GSE53624 | ZNF646 | 9726 | 53715 | 0.2471 | 0.0012 | |
| GSE63941 | ZNF646 | 9726 | 204876_at | 0.2555 | 0.0710 | |
| GSE77861 | ZNF646 | 9726 | 204876_at | 0.0481 | 0.8221 | |
| GSE97050 | ZNF646 | 9726 | A_33_P3239787 | -0.1646 | 0.4967 | |
| SRP007169 | ZNF646 | 9726 | RNAseq | -0.2992 | 0.6002 | |
| SRP008496 | ZNF646 | 9726 | RNAseq | -0.3191 | 0.3863 | |
| SRP064894 | ZNF646 | 9726 | RNAseq | 0.1700 | 0.1983 | |
| SRP133303 | ZNF646 | 9726 | RNAseq | 0.3724 | 0.0326 | |
| SRP159526 | ZNF646 | 9726 | RNAseq | 0.2184 | 0.2985 | |
| SRP193095 | ZNF646 | 9726 | RNAseq | 0.1147 | 0.2961 | |
| SRP219564 | ZNF646 | 9726 | RNAseq | 0.1143 | 0.6952 | |
| TCGA | ZNF646 | 9726 | RNAseq | -0.0261 | 0.5999 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZNF646 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF646:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF646 | 9726 | 5 | 5 | 20 | |
| GSE20123 | ZNF646 | 9726 | 5 | 4 | 21 | |
| GSE43470 | ZNF646 | 9726 | 3 | 3 | 37 | |
| GSE46452 | ZNF646 | 9726 | 38 | 1 | 20 | |
| GSE47630 | ZNF646 | 9726 | 11 | 7 | 22 | |
| GSE54993 | ZNF646 | 9726 | 2 | 5 | 63 | |
| GSE54994 | ZNF646 | 9726 | 5 | 9 | 39 | |
| GSE60625 | ZNF646 | 9726 | 4 | 0 | 7 | |
| GSE74703 | ZNF646 | 9726 | 3 | 2 | 31 | |
| GSE74704 | ZNF646 | 9726 | 3 | 2 | 15 | |
| TCGA | ZNF646 | 9726 | 20 | 10 | 66 |
Total number of gains: 99; Total number of losses: 48; Total Number of normals: 341.
Somatic mutations of ZNF646:
Generating mutation plots.
Highly correlated genes for ZNF646:
Showing top 20/658 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF646 | LRFN4 | 0.777 | 3 | 0 | 3 |
| ZNF646 | OPTC | 0.770589 | 3 | 0 | 3 |
| ZNF646 | CCDC28B | 0.766065 | 3 | 0 | 3 |
| ZNF646 | TMEM151A | 0.763244 | 4 | 0 | 4 |
| ZNF646 | HSD17B3 | 0.739355 | 3 | 0 | 3 |
| ZNF646 | WDR90 | 0.738162 | 3 | 0 | 3 |
| ZNF646 | GAS6-AS1 | 0.737307 | 3 | 0 | 3 |
| ZNF646 | COPS7B | 0.728059 | 3 | 0 | 3 |
| ZNF646 | KRTAP4-8 | 0.720363 | 3 | 0 | 3 |
| ZNF646 | SCUBE1 | 0.720058 | 5 | 0 | 5 |
| ZNF646 | TMEM221 | 0.719607 | 4 | 0 | 3 |
| ZNF646 | PDE6C | 0.717191 | 3 | 0 | 3 |
| ZNF646 | HID1 | 0.716416 | 4 | 0 | 3 |
| ZNF646 | KRT77 | 0.716198 | 3 | 0 | 3 |
| ZNF646 | SCARF2 | 0.715497 | 3 | 0 | 3 |
| ZNF646 | SPRED3 | 0.715222 | 7 | 0 | 6 |
| ZNF646 | RBBP8NL | 0.714109 | 3 | 0 | 3 |
| ZNF646 | STK32C | 0.713682 | 3 | 0 | 3 |
| ZNF646 | VWA5B2 | 0.711462 | 3 | 0 | 3 |
| ZNF646 | ZSWIM3 | 0.709448 | 3 | 0 | 3 |
For details and further investigation, click here
