| Full name: prostaglandin E receptor 1 | Alias Symbol: EP1 | ||
| Type: protein-coding gene | Cytoband: 19p13.1 | ||
| Entrez ID: 5731 | HGNC ID: HGNC:9593 | Ensembl Gene: ENSG00000160951 | OMIM ID: 176802 |
| Drug and gene relationship at DGIdb | |||
PTGER1 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04020 | Calcium signaling pathway |
Expression of PTGER1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PTGER1 | 5731 | 214391_x_at | -0.0316 | 0.8835 | |
| GSE20347 | PTGER1 | 5731 | 214391_x_at | 0.0054 | 0.9626 | |
| GSE23400 | PTGER1 | 5731 | 214391_x_at | -0.0960 | 0.0062 | |
| GSE26886 | PTGER1 | 5731 | 214391_x_at | 0.3731 | 0.0027 | |
| GSE29001 | PTGER1 | 5731 | 207650_x_at | -0.1771 | 0.2574 | |
| GSE38129 | PTGER1 | 5731 | 214391_x_at | -0.1475 | 0.0894 | |
| GSE45670 | PTGER1 | 5731 | 214391_x_at | 0.1100 | 0.2042 | |
| GSE53622 | PTGER1 | 5731 | 14520 | -0.1539 | 0.0206 | |
| GSE53624 | PTGER1 | 5731 | 14520 | 0.0125 | 0.8695 | |
| GSE63941 | PTGER1 | 5731 | 214391_x_at | -0.0095 | 0.9624 | |
| GSE77861 | PTGER1 | 5731 | 214391_x_at | -0.0806 | 0.5644 | |
| GSE97050 | PTGER1 | 5731 | A_23_P4808 | 0.1342 | 0.5869 | |
| SRP133303 | PTGER1 | 5731 | RNAseq | -1.7942 | 0.0000 | |
| SRP159526 | PTGER1 | 5731 | RNAseq | -0.1696 | 0.8007 | |
| SRP219564 | PTGER1 | 5731 | RNAseq | -0.2583 | 0.7263 | |
| TCGA | PTGER1 | 5731 | RNAseq | -0.8948 | 0.0026 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by PTGER1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PTGER1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PTGER1 | 5731 | 4 | 2 | 24 | |
| GSE20123 | PTGER1 | 5731 | 3 | 1 | 26 | |
| GSE43470 | PTGER1 | 5731 | 2 | 6 | 35 | |
| GSE46452 | PTGER1 | 5731 | 47 | 1 | 11 | |
| GSE47630 | PTGER1 | 5731 | 4 | 7 | 29 | |
| GSE54993 | PTGER1 | 5731 | 15 | 4 | 51 | |
| GSE54994 | PTGER1 | 5731 | 6 | 13 | 34 | |
| GSE60625 | PTGER1 | 5731 | 9 | 0 | 2 | |
| GSE74703 | PTGER1 | 5731 | 2 | 4 | 30 | |
| GSE74704 | PTGER1 | 5731 | 0 | 1 | 19 | |
| TCGA | PTGER1 | 5731 | 18 | 11 | 67 |
Total number of gains: 110; Total number of losses: 50; Total Number of normals: 328.
Somatic mutations of PTGER1:
Generating mutation plots.
Highly correlated genes for PTGER1:
Showing top 20/832 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PTGER1 | STK32C | 0.807726 | 3 | 0 | 3 |
| PTGER1 | RCOR2 | 0.801772 | 3 | 0 | 3 |
| PTGER1 | VAV2 | 0.75359 | 3 | 0 | 3 |
| PTGER1 | CPAMD8 | 0.753225 | 3 | 0 | 3 |
| PTGER1 | RASL10B | 0.746801 | 4 | 0 | 4 |
| PTGER1 | ADAMTS2 | 0.745455 | 3 | 0 | 3 |
| PTGER1 | TMEM255B | 0.726859 | 3 | 0 | 3 |
| PTGER1 | PTPRCAP | 0.721287 | 4 | 0 | 4 |
| PTGER1 | PAOX | 0.715697 | 3 | 0 | 3 |
| PTGER1 | ZNF697 | 0.71346 | 3 | 0 | 3 |
| PTGER1 | MAPK8IP2 | 0.711787 | 6 | 0 | 6 |
| PTGER1 | CHST13 | 0.707469 | 4 | 0 | 4 |
| PTGER1 | ARVCF | 0.70731 | 7 | 0 | 7 |
| PTGER1 | PPP1R12C | 0.701999 | 3 | 0 | 3 |
| PTGER1 | PLD4 | 0.701418 | 3 | 0 | 3 |
| PTGER1 | GPR39 | 0.698987 | 4 | 0 | 4 |
| PTGER1 | SIGIRR | 0.698554 | 3 | 0 | 3 |
| PTGER1 | CCDC28B | 0.697973 | 4 | 0 | 3 |
| PTGER1 | FAHD2A | 0.695814 | 3 | 0 | 3 |
| PTGER1 | TTC21A | 0.685957 | 3 | 0 | 3 |
For details and further investigation, click here
