| Full name: fuzzy planar cell polarity protein | Alias Symbol: FLJ22688|Fy|CPLANE3 | ||
| Type: protein-coding gene | Cytoband: 19q13.33 | ||
| Entrez ID: 80199 | HGNC ID: HGNC:26219 | Ensembl Gene: ENSG00000010361 | OMIM ID: 610622 |
| Drug and gene relationship at DGIdb | |||
Expression of FUZ:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FUZ | 80199 | 221187_s_at | 0.0082 | 0.9834 | |
| GSE20347 | FUZ | 80199 | 221187_s_at | -0.0187 | 0.8425 | |
| GSE23400 | FUZ | 80199 | 221187_s_at | -0.1465 | 0.0029 | |
| GSE26886 | FUZ | 80199 | 221187_s_at | 0.1954 | 0.1285 | |
| GSE29001 | FUZ | 80199 | 221187_s_at | -0.1113 | 0.5167 | |
| GSE38129 | FUZ | 80199 | 221187_s_at | -0.1250 | 0.2037 | |
| GSE45670 | FUZ | 80199 | 221187_s_at | -0.0808 | 0.4752 | |
| GSE63941 | FUZ | 80199 | 221187_s_at | 0.6419 | 0.3913 | |
| GSE77861 | FUZ | 80199 | 221187_s_at | -0.0273 | 0.8386 | |
| GSE97050 | FUZ | 80199 | A_23_P373568 | -0.1403 | 0.4630 | |
| SRP007169 | FUZ | 80199 | RNAseq | 0.0374 | 0.9365 | |
| SRP064894 | FUZ | 80199 | RNAseq | -0.0971 | 0.7943 | |
| SRP133303 | FUZ | 80199 | RNAseq | -0.8291 | 0.0104 | |
| SRP159526 | FUZ | 80199 | RNAseq | 0.6584 | 0.1139 | |
| SRP193095 | FUZ | 80199 | RNAseq | -0.2046 | 0.2665 | |
| SRP219564 | FUZ | 80199 | RNAseq | -0.8133 | 0.1417 | |
| TCGA | FUZ | 80199 | RNAseq | -0.1023 | 0.5702 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FUZ expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of FUZ:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FUZ | 80199 | 4 | 4 | 22 | |
| GSE20123 | FUZ | 80199 | 4 | 3 | 23 | |
| GSE43470 | FUZ | 80199 | 5 | 11 | 27 | |
| GSE46452 | FUZ | 80199 | 45 | 1 | 13 | |
| GSE47630 | FUZ | 80199 | 10 | 6 | 24 | |
| GSE54993 | FUZ | 80199 | 17 | 4 | 49 | |
| GSE54994 | FUZ | 80199 | 4 | 14 | 35 | |
| GSE60625 | FUZ | 80199 | 9 | 0 | 2 | |
| GSE74703 | FUZ | 80199 | 5 | 7 | 24 | |
| GSE74704 | FUZ | 80199 | 4 | 1 | 15 | |
| TCGA | FUZ | 80199 | 14 | 18 | 64 |
Total number of gains: 121; Total number of losses: 69; Total Number of normals: 298.
Somatic mutations of FUZ:
Generating mutation plots.
Highly correlated genes for FUZ:
Showing top 20/340 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FUZ | RASL10B | 0.817036 | 3 | 0 | 3 |
| FUZ | ZNF569 | 0.801261 | 3 | 0 | 3 |
| FUZ | LENG1 | 0.77762 | 3 | 0 | 3 |
| FUZ | GPR39 | 0.768681 | 3 | 0 | 3 |
| FUZ | DNAJB8 | 0.765297 | 3 | 0 | 3 |
| FUZ | ISLR2 | 0.764968 | 3 | 0 | 3 |
| FUZ | NKAIN4 | 0.760606 | 3 | 0 | 3 |
| FUZ | SPATA2L | 0.752516 | 3 | 0 | 3 |
| FUZ | TMUB1 | 0.750272 | 3 | 0 | 3 |
| FUZ | ADAP1 | 0.743658 | 3 | 0 | 3 |
| FUZ | DUSP15 | 0.741923 | 3 | 0 | 3 |
| FUZ | ING5 | 0.736796 | 3 | 0 | 3 |
| FUZ | CNPY1 | 0.731408 | 3 | 0 | 3 |
| FUZ | KIRREL2 | 0.730144 | 3 | 0 | 3 |
| FUZ | TDRD10 | 0.728322 | 3 | 0 | 3 |
| FUZ | CCDC28B | 0.725509 | 4 | 0 | 4 |
| FUZ | RCOR2 | 0.72486 | 4 | 0 | 4 |
| FUZ | ZBTB32 | 0.718426 | 3 | 0 | 3 |
| FUZ | SCARF2 | 0.717531 | 3 | 0 | 3 |
| FUZ | EXOG | 0.714013 | 3 | 0 | 3 |
For details and further investigation, click here
