| Full name: rhophilin Rho GTPase binding protein 1 | Alias Symbol: KIAA1929|RHPN|ODF5 | ||
| Type: protein-coding gene | Cytoband: 8q24.3 | ||
| Entrez ID: 114822 | HGNC ID: HGNC:19973 | Ensembl Gene: ENSG00000158106 | OMIM ID: 601031 |
| Drug and gene relationship at DGIdb | |||
Expression of RHPN1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RHPN1 | 114822 | 235998_at | 0.1783 | 0.6192 | |
| GSE26886 | RHPN1 | 114822 | 228405_at | 0.4669 | 0.0018 | |
| GSE45670 | RHPN1 | 114822 | 228405_at | 0.0400 | 0.7128 | |
| GSE53622 | RHPN1 | 114822 | 5031 | 0.7412 | 0.0000 | |
| GSE53624 | RHPN1 | 114822 | 5031 | 1.1643 | 0.0000 | |
| GSE63941 | RHPN1 | 114822 | 228405_at | 0.2754 | 0.0892 | |
| GSE77861 | RHPN1 | 114822 | 228405_at | -0.0214 | 0.8990 | |
| GSE97050 | RHPN1 | 114822 | A_33_P3387616 | 0.4833 | 0.1470 | |
| SRP064894 | RHPN1 | 114822 | RNAseq | 1.3654 | 0.0000 | |
| SRP133303 | RHPN1 | 114822 | RNAseq | 0.2834 | 0.4571 | |
| SRP159526 | RHPN1 | 114822 | RNAseq | 1.5329 | 0.0116 | |
| SRP193095 | RHPN1 | 114822 | RNAseq | 0.7086 | 0.0013 | |
| SRP219564 | RHPN1 | 114822 | RNAseq | 1.5645 | 0.0686 | |
| TCGA | RHPN1 | 114822 | RNAseq | 0.2300 | 0.1940 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by RHPN1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RHPN1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RHPN1 | 114822 | 17 | 1 | 12 | |
| GSE20123 | RHPN1 | 114822 | 17 | 1 | 12 | |
| GSE43470 | RHPN1 | 114822 | 17 | 2 | 24 | |
| GSE46452 | RHPN1 | 114822 | 27 | 0 | 32 | |
| GSE47630 | RHPN1 | 114822 | 23 | 1 | 16 | |
| GSE54993 | RHPN1 | 114822 | 0 | 25 | 45 | |
| GSE54994 | RHPN1 | 114822 | 39 | 1 | 13 | |
| GSE60625 | RHPN1 | 114822 | 3 | 4 | 4 | |
| GSE74703 | RHPN1 | 114822 | 15 | 1 | 20 | |
| GSE74704 | RHPN1 | 114822 | 10 | 0 | 10 | |
| TCGA | RHPN1 | 114822 | 64 | 2 | 30 |
Total number of gains: 232; Total number of losses: 38; Total Number of normals: 218.
Somatic mutations of RHPN1:
Generating mutation plots.
Highly correlated genes for RHPN1:
Showing top 20/536 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RHPN1 | GGTLC1 | 0.780304 | 3 | 0 | 3 |
| RHPN1 | PGC | 0.776447 | 3 | 0 | 3 |
| RHPN1 | GRAP | 0.746884 | 3 | 0 | 3 |
| RHPN1 | LTB4R2 | 0.738317 | 4 | 0 | 4 |
| RHPN1 | PGAM2 | 0.72706 | 3 | 0 | 3 |
| RHPN1 | CCDC28B | 0.726613 | 4 | 0 | 4 |
| RHPN1 | MS4A18 | 0.717539 | 3 | 0 | 3 |
| RHPN1 | MAPK8IP2 | 0.713165 | 4 | 0 | 4 |
| RHPN1 | BEST3 | 0.713069 | 3 | 0 | 3 |
| RHPN1 | FRS3 | 0.713026 | 3 | 0 | 3 |
| RHPN1 | ZNF580 | 0.705109 | 3 | 0 | 3 |
| RHPN1 | TMEM235 | 0.699805 | 3 | 0 | 3 |
| RHPN1 | GNB3 | 0.694968 | 4 | 0 | 4 |
| RHPN1 | LRFN4 | 0.693927 | 5 | 0 | 4 |
| RHPN1 | SLC34A1 | 0.691473 | 3 | 0 | 3 |
| RHPN1 | ZIC1 | 0.690567 | 5 | 0 | 4 |
| RHPN1 | C2CD4D | 0.690146 | 3 | 0 | 3 |
| RHPN1 | DUOXA2 | 0.689848 | 3 | 0 | 3 |
| RHPN1 | MRGPRG | 0.689289 | 3 | 0 | 3 |
| RHPN1 | ZNF524 | 0.688488 | 5 | 0 | 4 |
For details and further investigation, click here
