| Full name: chromodomain helicase DNA binding protein 5 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1p36.31 | ||
| Entrez ID: 26038 | HGNC ID: HGNC:16816 | Ensembl Gene: ENSG00000116254 | OMIM ID: 610771 |
| Drug and gene relationship at DGIdb | |||
Expression of CHD5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CHD5 | 26038 | 213965_s_at | -0.3100 | 0.6488 | |
| GSE20347 | CHD5 | 26038 | 213965_s_at | -0.0166 | 0.8199 | |
| GSE23400 | CHD5 | 26038 | 213965_s_at | -0.2104 | 0.0000 | |
| GSE26886 | CHD5 | 26038 | 213965_s_at | 0.3102 | 0.0173 | |
| GSE29001 | CHD5 | 26038 | 217250_s_at | -0.1073 | 0.5867 | |
| GSE38129 | CHD5 | 26038 | 213965_s_at | -0.2818 | 0.0411 | |
| GSE45670 | CHD5 | 26038 | 213965_s_at | -0.1233 | 0.1519 | |
| GSE53622 | CHD5 | 26038 | 42490 | 0.3669 | 0.0001 | |
| GSE53624 | CHD5 | 26038 | 42490 | -0.0427 | 0.6516 | |
| GSE63941 | CHD5 | 26038 | 213965_s_at | -0.1701 | 0.2634 | |
| GSE77861 | CHD5 | 26038 | 213965_s_at | -0.0990 | 0.4731 | |
| GSE97050 | CHD5 | 26038 | A_33_P3419321 | -0.0605 | 0.8268 | |
| SRP133303 | CHD5 | 26038 | RNAseq | -1.0840 | 0.1499 | |
| SRP219564 | CHD5 | 26038 | RNAseq | 0.0105 | 0.9928 | |
| TCGA | CHD5 | 26038 | RNAseq | -1.8782 | 0.0019 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by CHD5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CHD5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CHD5 | 26038 | 3 | 6 | 21 | |
| GSE20123 | CHD5 | 26038 | 3 | 5 | 22 | |
| GSE43470 | CHD5 | 26038 | 6 | 5 | 32 | |
| GSE46452 | CHD5 | 26038 | 7 | 1 | 51 | |
| GSE47630 | CHD5 | 26038 | 8 | 4 | 28 | |
| GSE54993 | CHD5 | 26038 | 3 | 2 | 65 | |
| GSE54994 | CHD5 | 26038 | 14 | 3 | 36 | |
| GSE60625 | CHD5 | 26038 | 0 | 0 | 11 | |
| GSE74703 | CHD5 | 26038 | 5 | 3 | 28 | |
| GSE74704 | CHD5 | 26038 | 3 | 0 | 17 | |
| TCGA | CHD5 | 26038 | 12 | 22 | 62 |
Total number of gains: 64; Total number of losses: 51; Total Number of normals: 373.
Somatic mutations of CHD5:
Generating mutation plots.
Highly correlated genes for CHD5:
Showing top 20/961 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CHD5 | DCDC1 | 0.850099 | 3 | 0 | 3 |
| CHD5 | PLA2G2C | 0.823355 | 3 | 0 | 3 |
| CHD5 | TSPAN11 | 0.81664 | 3 | 0 | 3 |
| CHD5 | C1QL2 | 0.807724 | 3 | 0 | 3 |
| CHD5 | TEF | 0.800252 | 3 | 0 | 3 |
| CHD5 | SUN5 | 0.796878 | 3 | 0 | 3 |
| CHD5 | YY2 | 0.792429 | 3 | 0 | 3 |
| CHD5 | ADAM21 | 0.78928 | 3 | 0 | 3 |
| CHD5 | BBC3 | 0.783577 | 3 | 0 | 3 |
| CHD5 | DPP6 | 0.782166 | 4 | 0 | 4 |
| CHD5 | MRGPRG | 0.778093 | 3 | 0 | 3 |
| CHD5 | FRRS1L | 0.77649 | 3 | 0 | 3 |
| CHD5 | CHMP6 | 0.77559 | 4 | 0 | 4 |
| CHD5 | KLHL26 | 0.773569 | 3 | 0 | 3 |
| CHD5 | CELF4 | 0.773269 | 3 | 0 | 3 |
| CHD5 | STK32C | 0.770052 | 3 | 0 | 3 |
| CHD5 | ITGA2B | 0.769753 | 4 | 0 | 4 |
| CHD5 | SLC39A5 | 0.766439 | 4 | 0 | 4 |
| CHD5 | SPACA3 | 0.76392 | 4 | 0 | 4 |
| CHD5 | PRR18 | 0.761871 | 3 | 0 | 3 |
For details and further investigation, click here
