| Full name: dipeptidyl peptidase like 6 | Alias Symbol: DPPX|DPL1 | ||
| Type: protein-coding gene | Cytoband: 7q36.2 | ||
| Entrez ID: 1804 | HGNC ID: HGNC:3010 | Ensembl Gene: ENSG00000130226 | OMIM ID: 126141 |
| Drug and gene relationship at DGIdb | |||
Expression of DPP6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DPP6 | 1804 | 1554796_at | -0.0654 | 0.8113 | |
| GSE20347 | DPP6 | 1804 | 207789_s_at | -0.0101 | 0.9137 | |
| GSE23400 | DPP6 | 1804 | 207789_s_at | -0.1690 | 0.0004 | |
| GSE26886 | DPP6 | 1804 | 1554796_at | -0.2066 | 0.1442 | |
| GSE29001 | DPP6 | 1804 | 207789_s_at | -0.1227 | 0.4725 | |
| GSE38129 | DPP6 | 1804 | 207789_s_at | -0.5004 | 0.0031 | |
| GSE45670 | DPP6 | 1804 | 207789_s_at | 0.0931 | 0.3394 | |
| GSE53622 | DPP6 | 1804 | 9489 | -0.5502 | 0.0009 | |
| GSE53624 | DPP6 | 1804 | 9489 | -0.2763 | 0.0018 | |
| GSE63941 | DPP6 | 1804 | 1554796_at | 0.0900 | 0.6751 | |
| GSE77861 | DPP6 | 1804 | 1554796_at | 0.0181 | 0.9107 | |
| GSE97050 | DPP6 | 1804 | A_23_P170888 | -0.8872 | 0.2155 | |
| SRP133303 | DPP6 | 1804 | RNAseq | -0.8371 | 0.0963 | |
| SRP159526 | DPP6 | 1804 | RNAseq | -0.4295 | 0.4984 | |
| SRP219564 | DPP6 | 1804 | RNAseq | -1.0781 | 0.3068 | |
| TCGA | DPP6 | 1804 | RNAseq | -2.2629 | 0.0013 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by DPP6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DPP6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DPP6 | 1804 | 3 | 3 | 24 | |
| GSE20123 | DPP6 | 1804 | 2 | 3 | 25 | |
| GSE43470 | DPP6 | 1804 | 2 | 5 | 36 | |
| GSE46452 | DPP6 | 1804 | 7 | 2 | 50 | |
| GSE47630 | DPP6 | 1804 | 6 | 9 | 25 | |
| GSE54993 | DPP6 | 1804 | 3 | 3 | 64 | |
| GSE54994 | DPP6 | 1804 | 6 | 8 | 39 | |
| GSE60625 | DPP6 | 1804 | 0 | 0 | 11 | |
| GSE74703 | DPP6 | 1804 | 2 | 4 | 30 | |
| GSE74704 | DPP6 | 1804 | 0 | 3 | 17 | |
| TCGA | DPP6 | 1804 | 27 | 27 | 42 |
Total number of gains: 58; Total number of losses: 67; Total Number of normals: 363.
Somatic mutations of DPP6:
Generating mutation plots.
Highly correlated genes for DPP6:
Showing top 20/489 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DPP6 | CHD5 | 0.782166 | 4 | 0 | 4 |
| DPP6 | CD300LB | 0.72559 | 3 | 0 | 3 |
| DPP6 | SYPL2 | 0.702943 | 5 | 0 | 4 |
| DPP6 | ASB10 | 0.689458 | 4 | 0 | 4 |
| DPP6 | SMPX | 0.677887 | 7 | 0 | 6 |
| DPP6 | ASTN1 | 0.672674 | 4 | 0 | 4 |
| DPP6 | KLHL41 | 0.670558 | 4 | 0 | 4 |
| DPP6 | RNF167 | 0.667724 | 4 | 0 | 3 |
| DPP6 | STARD13-AS | 0.666156 | 3 | 0 | 3 |
| DPP6 | MATN1 | 0.662994 | 4 | 0 | 3 |
| DPP6 | ASIC5 | 0.661124 | 3 | 0 | 3 |
| DPP6 | CER1 | 0.659855 | 4 | 0 | 4 |
| DPP6 | NCR3 | 0.659769 | 4 | 0 | 3 |
| DPP6 | ENOX1 | 0.659049 | 4 | 0 | 4 |
| DPP6 | CPN1 | 0.658455 | 3 | 0 | 3 |
| DPP6 | CCL25 | 0.657198 | 5 | 0 | 5 |
| DPP6 | CCDC62 | 0.65501 | 3 | 0 | 3 |
| DPP6 | USH1C | 0.65453 | 5 | 0 | 4 |
| DPP6 | POM121L12 | 0.652757 | 3 | 0 | 3 |
| DPP6 | MAP3K19 | 0.652215 | 5 | 0 | 5 |
For details and further investigation, click here
