| Full name: sperm acrosome associated 3 | Alias Symbol: ALLP17|SLLP1|LYC3|LYZL3|CT54 | ||
| Type: protein-coding gene | Cytoband: 17q11.2 | ||
| Entrez ID: 124912 | HGNC ID: HGNC:16260 | Ensembl Gene: ENSG00000141316 | OMIM ID: 612749 |
| Drug and gene relationship at DGIdb | |||
Expression of SPACA3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SPACA3 | 124912 | 243621_at | 0.0264 | 0.9348 | |
| GSE26886 | SPACA3 | 124912 | 243621_at | 0.1337 | 0.3395 | |
| GSE45670 | SPACA3 | 124912 | 243621_at | 0.0816 | 0.4378 | |
| GSE53622 | SPACA3 | 124912 | 102037 | 0.0592 | 0.5006 | |
| GSE53624 | SPACA3 | 124912 | 102037 | 0.0574 | 0.6865 | |
| GSE63941 | SPACA3 | 124912 | 243621_at | -0.1161 | 0.3727 | |
| GSE77861 | SPACA3 | 124912 | 243621_at | -0.1023 | 0.6191 | |
| GSE97050 | SPACA3 | 124912 | A_23_P317244 | 0.0414 | 0.8657 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SPACA3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SPACA3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SPACA3 | 124912 | 7 | 1 | 22 | |
| GSE20123 | SPACA3 | 124912 | 7 | 1 | 22 | |
| GSE43470 | SPACA3 | 124912 | 0 | 1 | 42 | |
| GSE46452 | SPACA3 | 124912 | 34 | 0 | 25 | |
| GSE47630 | SPACA3 | 124912 | 7 | 1 | 32 | |
| GSE54993 | SPACA3 | 124912 | 3 | 3 | 64 | |
| GSE54994 | SPACA3 | 124912 | 7 | 6 | 40 | |
| GSE60625 | SPACA3 | 124912 | 4 | 0 | 7 | |
| GSE74703 | SPACA3 | 124912 | 0 | 1 | 35 | |
| GSE74704 | SPACA3 | 124912 | 4 | 1 | 15 | |
| TCGA | SPACA3 | 124912 | 22 | 7 | 67 |
Total number of gains: 95; Total number of losses: 22; Total Number of normals: 371.
Somatic mutations of SPACA3:
Generating mutation plots.
Highly correlated genes for SPACA3:
Showing top 20/477 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SPACA3 | GH1 | 0.903322 | 3 | 0 | 3 |
| SPACA3 | GRIK4 | 0.895008 | 3 | 0 | 3 |
| SPACA3 | STRC | 0.888362 | 3 | 0 | 3 |
| SPACA3 | BTNL2 | 0.880375 | 3 | 0 | 3 |
| SPACA3 | IL1F10 | 0.872877 | 3 | 0 | 3 |
| SPACA3 | OR2H1 | 0.856451 | 3 | 0 | 3 |
| SPACA3 | LRIT1 | 0.854941 | 3 | 0 | 3 |
| SPACA3 | ANKDD1A | 0.854879 | 3 | 0 | 3 |
| SPACA3 | DCDC1 | 0.851496 | 3 | 0 | 3 |
| SPACA3 | PLA2G2C | 0.849464 | 3 | 0 | 3 |
| SPACA3 | KCTD19 | 0.848658 | 3 | 0 | 3 |
| SPACA3 | NKX6-3 | 0.845402 | 3 | 0 | 3 |
| SPACA3 | CNOT3 | 0.835604 | 3 | 0 | 3 |
| SPACA3 | ZNF329 | 0.829752 | 3 | 0 | 3 |
| SPACA3 | PVALB | 0.822954 | 3 | 0 | 3 |
| SPACA3 | ATP2B2 | 0.820593 | 4 | 0 | 4 |
| SPACA3 | TTC12 | 0.816056 | 3 | 0 | 3 |
| SPACA3 | TXNDC2 | 0.815986 | 3 | 0 | 3 |
| SPACA3 | BTBD19 | 0.810895 | 3 | 0 | 3 |
| SPACA3 | YY2 | 0.809202 | 3 | 0 | 3 |
For details and further investigation, click here
