| Full name: proline rich 18 | Alias Symbol: MGC35308 | ||
| Type: protein-coding gene | Cytoband: 6q27 | ||
| Entrez ID: 285800 | HGNC ID: HGNC:28574 | Ensembl Gene: ENSG00000176381 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of PRR18:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PRR18 | 285800 | 238008_at | 0.1756 | 0.3366 | |
| GSE26886 | PRR18 | 285800 | 238008_at | 0.6282 | 0.0289 | |
| GSE45670 | PRR18 | 285800 | 238008_at | 0.2094 | 0.1451 | |
| GSE53622 | PRR18 | 285800 | 3197 | 0.1069 | 0.1509 | |
| GSE53624 | PRR18 | 285800 | 3197 | 0.0978 | 0.3826 | |
| GSE63941 | PRR18 | 285800 | 238008_at | 0.2781 | 0.7145 | |
| GSE77861 | PRR18 | 285800 | 238008_at | -0.0174 | 0.8712 | |
| GSE97050 | PRR18 | 285800 | A_32_P407293 | 0.1250 | 0.5823 | |
| TCGA | PRR18 | 285800 | RNAseq | 1.7716 | 0.0192 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by PRR18 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PRR18:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PRR18 | 285800 | 2 | 6 | 22 | |
| GSE20123 | PRR18 | 285800 | 2 | 6 | 22 | |
| GSE43470 | PRR18 | 285800 | 3 | 0 | 40 | |
| GSE46452 | PRR18 | 285800 | 3 | 10 | 46 | |
| GSE47630 | PRR18 | 285800 | 7 | 7 | 26 | |
| GSE54993 | PRR18 | 285800 | 4 | 3 | 63 | |
| GSE54994 | PRR18 | 285800 | 9 | 8 | 36 | |
| GSE60625 | PRR18 | 285800 | 1 | 1 | 9 | |
| GSE74703 | PRR18 | 285800 | 3 | 0 | 33 | |
| GSE74704 | PRR18 | 285800 | 1 | 3 | 16 | |
| TCGA | PRR18 | 285800 | 13 | 21 | 62 |
Total number of gains: 48; Total number of losses: 65; Total Number of normals: 375.
Somatic mutations of PRR18:
Generating mutation plots.
Highly correlated genes for PRR18:
Showing top 20/234 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PRR18 | C1QL2 | 0.807471 | 3 | 0 | 3 |
| PRR18 | GRIK4 | 0.789503 | 3 | 0 | 3 |
| PRR18 | MYOZ3 | 0.784524 | 3 | 0 | 3 |
| PRR18 | SHISA7 | 0.78123 | 3 | 0 | 3 |
| PRR18 | DCDC1 | 0.779358 | 3 | 0 | 3 |
| PRR18 | HK3 | 0.775956 | 3 | 0 | 3 |
| PRR18 | STRC | 0.767814 | 3 | 0 | 3 |
| PRR18 | CHD5 | 0.761871 | 3 | 0 | 3 |
| PRR18 | FGF22 | 0.761037 | 3 | 0 | 3 |
| PRR18 | PABPN1L | 0.75867 | 3 | 0 | 3 |
| PRR18 | KRTAP4-1 | 0.75459 | 3 | 0 | 3 |
| PRR18 | APBA2 | 0.751303 | 3 | 0 | 3 |
| PRR18 | SUN5 | 0.750366 | 4 | 0 | 4 |
| PRR18 | NPPA | 0.75021 | 3 | 0 | 3 |
| PRR18 | CLSTN3 | 0.749182 | 3 | 0 | 3 |
| PRR18 | KCNH3 | 0.745726 | 3 | 0 | 3 |
| PRR18 | STAC3 | 0.745413 | 3 | 0 | 3 |
| PRR18 | LTK | 0.744027 | 3 | 0 | 3 |
| PRR18 | AGRP | 0.743677 | 3 | 0 | 3 |
| PRR18 | EVX1 | 0.742732 | 3 | 0 | 3 |
For details and further investigation, click here
