| Full name: kelch like family member 26 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 19p13.11 | ||
| Entrez ID: 55295 | HGNC ID: HGNC:25623 | Ensembl Gene: ENSG00000167487 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of KLHL26:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KLHL26 | 55295 | 219354_at | 0.0024 | 0.9979 | |
| GSE20347 | KLHL26 | 55295 | 219354_at | 0.3137 | 0.0018 | |
| GSE23400 | KLHL26 | 55295 | 219354_at | 0.1225 | 0.0947 | |
| GSE26886 | KLHL26 | 55295 | 219354_at | 0.8385 | 0.0005 | |
| GSE29001 | KLHL26 | 55295 | 219354_at | 0.2800 | 0.2238 | |
| GSE38129 | KLHL26 | 55295 | 219354_at | 0.0458 | 0.7566 | |
| GSE45670 | KLHL26 | 55295 | 219354_at | -0.0898 | 0.5951 | |
| GSE53622 | KLHL26 | 55295 | 8194 | -0.3539 | 0.0000 | |
| GSE53624 | KLHL26 | 55295 | 8194 | -0.1885 | 0.0042 | |
| GSE63941 | KLHL26 | 55295 | 219354_at | 0.3535 | 0.4978 | |
| GSE77861 | KLHL26 | 55295 | 219354_at | 0.4231 | 0.0129 | |
| GSE97050 | KLHL26 | 55295 | A_23_P39375 | -0.0569 | 0.8844 | |
| SRP007169 | KLHL26 | 55295 | RNAseq | 0.8891 | 0.1529 | |
| SRP064894 | KLHL26 | 55295 | RNAseq | -0.0406 | 0.8740 | |
| SRP133303 | KLHL26 | 55295 | RNAseq | -0.0366 | 0.8157 | |
| SRP159526 | KLHL26 | 55295 | RNAseq | 0.1291 | 0.6341 | |
| SRP193095 | KLHL26 | 55295 | RNAseq | 0.1570 | 0.2365 | |
| SRP219564 | KLHL26 | 55295 | RNAseq | -0.1687 | 0.7415 | |
| TCGA | KLHL26 | 55295 | RNAseq | -0.1530 | 0.0148 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by KLHL26 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KLHL26:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KLHL26 | 55295 | 4 | 5 | 21 | |
| GSE20123 | KLHL26 | 55295 | 3 | 3 | 24 | |
| GSE43470 | KLHL26 | 55295 | 2 | 5 | 36 | |
| GSE46452 | KLHL26 | 55295 | 47 | 1 | 11 | |
| GSE47630 | KLHL26 | 55295 | 4 | 8 | 28 | |
| GSE54993 | KLHL26 | 55295 | 15 | 4 | 51 | |
| GSE54994 | KLHL26 | 55295 | 6 | 13 | 34 | |
| GSE60625 | KLHL26 | 55295 | 9 | 0 | 2 | |
| GSE74703 | KLHL26 | 55295 | 2 | 3 | 31 | |
| GSE74704 | KLHL26 | 55295 | 0 | 3 | 17 | |
| TCGA | KLHL26 | 55295 | 16 | 10 | 70 |
Total number of gains: 108; Total number of losses: 55; Total Number of normals: 325.
Somatic mutations of KLHL26:
Generating mutation plots.
Highly correlated genes for KLHL26:
Showing top 20/229 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KLHL26 | BMF | 0.805751 | 3 | 0 | 3 |
| KLHL26 | CHD5 | 0.773569 | 3 | 0 | 3 |
| KLHL26 | BEND3 | 0.773243 | 3 | 0 | 3 |
| KLHL26 | GTF2IRD2 | 0.771146 | 3 | 0 | 3 |
| KLHL26 | SLC6A3 | 0.771075 | 3 | 0 | 3 |
| KLHL26 | ALKBH5 | 0.768648 | 3 | 0 | 3 |
| KLHL26 | LENG1 | 0.746024 | 3 | 0 | 3 |
| KLHL26 | FLAD1 | 0.744723 | 3 | 0 | 3 |
| KLHL26 | KRTAP4-1 | 0.732205 | 3 | 0 | 3 |
| KLHL26 | TNFAIP8L1 | 0.732083 | 3 | 0 | 3 |
| KLHL26 | CHP2 | 0.73115 | 3 | 0 | 3 |
| KLHL26 | JAKMIP3 | 0.714927 | 3 | 0 | 3 |
| KLHL26 | BTBD3 | 0.714023 | 3 | 0 | 3 |
| KLHL26 | HOXC9 | 0.711456 | 3 | 0 | 3 |
| KLHL26 | SCN9A | 0.706905 | 3 | 0 | 3 |
| KLHL26 | FBXL15 | 0.706737 | 4 | 0 | 4 |
| KLHL26 | ZFPM1 | 0.706555 | 3 | 0 | 3 |
| KLHL26 | ISCU | 0.689326 | 4 | 0 | 3 |
| KLHL26 | EPB41L4B | 0.684336 | 4 | 0 | 4 |
| KLHL26 | C19orf25 | 0.683001 | 3 | 0 | 3 |
For details and further investigation, click here
