CHRND

 

Full name: cholinergic receptor nicotinic delta subunit Alias Symbol: 
Type: protein-coding gene Cytoband: 2q37.1
Entrez ID: 1144 HGNC ID: HGNC:1965 Ensembl Gene: ENSG00000135902 OMIM ID: 100720
Drug and gene relationship at DGIdb

 

Expression of CHRND:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 CHRND 1144 207024_at -0.0839 0.6758
GSE20347 CHRND 1144 207024_at -0.0797 0.2751
GSE23400 CHRND 1144 207024_at -0.1238 0.0001
GSE26886 CHRND 1144 207024_at 0.0211 0.9083
GSE29001 CHRND 1144 207024_at -0.1983 0.1058
GSE38129 CHRND 1144 207024_at -0.2115 0.0008
GSE45670 CHRND 1144 207024_at 0.0284 0.8170
GSE53622 CHRND 1144 11196 -0.4050 0.0000
GSE53624 CHRND 1144 11196 -0.5854 0.0000
GSE63941 CHRND 1144 207024_at 0.2740 0.0817
GSE77861 CHRND 1144 207024_at -0.0440 0.6684
GSE97050 CHRND 1144 A_23_P430558 -0.0945 0.7192
SRP133303 CHRND 1144 RNAseq 0.5924 0.0718

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by CHRND expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of CHRND:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 CHRND 1144 1 12 17
GSE20123 CHRND 1144 1 12 17
GSE43470 CHRND 1144 1 8 34
GSE46452 CHRND 1144 0 5 54
GSE47630 CHRND 1144 4 5 31
GSE54993 CHRND 1144 3 2 65
GSE54994 CHRND 1144 6 10 37
GSE60625 CHRND 1144 0 3 8
GSE74703 CHRND 1144 1 6 29
GSE74704 CHRND 1144 1 5 14
TCGA CHRND 1144 11 29 56

Total number of gains: 29; Total number of losses: 97; Total Number of normals: 362.  


 

Somatic mutations of CHRND:

 

Generating mutation plots.

 

Highly correlated genes for CHRND:

 

Showing top 20/913 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
CHRNDOR13G10.84523303
CHRNDKRTAP6-10.840086303
CHRNDTPRX10.785304303
CHRNDBARHL20.781142303
CHRNDABCC60.771431303
CHRNDMFSD2B0.767377303
CHRNDOR51T10.75699303
CHRNDSHC20.752197303
CHRNDOR2Z10.751819303
CHRNDALPL0.749865303
CHRNDMRGPRE0.746568303
CHRNDOR10G30.744647303
CHRNDTDGF10.742706303
CHRNDKRTAP20-10.730629303
CHRNDCCDC620.726179303
CHRNDCELF50.723923303
CHRNDPKLR0.72304404
CHRNDODF40.722813404
CHRNDOR4C30.722501303
CHRNDKRTAP5-40.714245303

For details and further investigation, click here