| Full name: olfactory receptor family 4 subfamily C member 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 11p11.2 | ||
| Entrez ID: 256144 | HGNC ID: HGNC:14697 | Ensembl Gene: ENSG00000176547 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
OR4C3 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04740 | Olfactory transduction |
Expression of OR4C3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | OR4C3 | 256144 | 95410 | -0.1824 | 0.0173 | |
| GSE53624 | OR4C3 | 256144 | 95410 | -0.1532 | 0.0439 | |
| GSE97050 | OR4C3 | 256144 | A_23_P2077 | -0.2732 | 0.2329 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by OR4C3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of OR4C3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | OR4C3 | 256144 | 2 | 9 | 19 | |
| GSE20123 | OR4C3 | 256144 | 1 | 8 | 21 | |
| GSE43470 | OR4C3 | 256144 | 1 | 4 | 38 | |
| GSE46452 | OR4C3 | 256144 | 9 | 5 | 45 | |
| GSE47630 | OR4C3 | 256144 | 3 | 10 | 27 | |
| GSE54993 | OR4C3 | 256144 | 3 | 0 | 67 | |
| GSE54994 | OR4C3 | 256144 | 1 | 11 | 41 | |
| GSE60625 | OR4C3 | 256144 | 0 | 0 | 11 | |
| GSE74703 | OR4C3 | 256144 | 1 | 2 | 33 | |
| GSE74704 | OR4C3 | 256144 | 1 | 6 | 13 | |
| TCGA | OR4C3 | 256144 | 12 | 19 | 65 |
Total number of gains: 34; Total number of losses: 74; Total Number of normals: 380.
Somatic mutations of OR4C3:
Generating mutation plots.
Highly correlated genes for OR4C3:
Showing top 20/120 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| OR4C3 | KRTAP6-1 | 0.803682 | 3 | 0 | 3 |
| OR4C3 | AQP8 | 0.797195 | 3 | 0 | 3 |
| OR4C3 | GRM1 | 0.791813 | 3 | 0 | 3 |
| OR4C3 | KCNJ13 | 0.790324 | 3 | 0 | 3 |
| OR4C3 | PRG3 | 0.77599 | 3 | 0 | 3 |
| OR4C3 | SLC22A12 | 0.774776 | 3 | 0 | 3 |
| OR4C3 | KRTAP4-8 | 0.759387 | 3 | 0 | 3 |
| OR4C3 | PRSS38 | 0.757824 | 3 | 0 | 3 |
| OR4C3 | PSPN | 0.75209 | 3 | 0 | 3 |
| OR4C3 | RNF180 | 0.747707 | 3 | 0 | 3 |
| OR4C3 | YY2 | 0.745363 | 3 | 0 | 3 |
| OR4C3 | SLC22A31 | 0.74064 | 3 | 0 | 3 |
| OR4C3 | OTOG | 0.740374 | 3 | 0 | 3 |
| OR4C3 | NOBOX | 0.739572 | 3 | 0 | 3 |
| OR4C3 | PDZRN3 | 0.739328 | 3 | 0 | 3 |
| OR4C3 | PAX2 | 0.73857 | 3 | 0 | 3 |
| OR4C3 | INSC | 0.737167 | 3 | 0 | 3 |
| OR4C3 | TXNDC2 | 0.735295 | 3 | 0 | 3 |
| OR4C3 | LRSAM1 | 0.734977 | 3 | 0 | 3 |
| OR4C3 | PKD2L1 | 0.734803 | 3 | 0 | 3 |
For details and further investigation, click here
