| Full name: C-type lectin domain family 4 member M | Alias Symbol: HP10347|DC-SIGNR|LSIGN|DCSIGNR|DC-SIGN2 | ||
| Type: protein-coding gene | Cytoband: 19p13.2 | ||
| Entrez ID: 10332 | HGNC ID: HGNC:13523 | Ensembl Gene: ENSG00000104938 | OMIM ID: 605872 |
| Drug and gene relationship at DGIdb | |||
CLEC4M involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa05152 | Tuberculosis |
Expression of CLEC4M:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CLEC4M | 10332 | 207995_s_at | 0.0912 | 0.6008 | |
| GSE20347 | CLEC4M | 10332 | 207995_s_at | -0.0194 | 0.8075 | |
| GSE23400 | CLEC4M | 10332 | 210481_s_at | -0.1128 | 0.0068 | |
| GSE26886 | CLEC4M | 10332 | 207995_s_at | 0.1843 | 0.1264 | |
| GSE29001 | CLEC4M | 10332 | 210481_s_at | -0.1500 | 0.2597 | |
| GSE38129 | CLEC4M | 10332 | 210481_s_at | -0.1367 | 0.0128 | |
| GSE45670 | CLEC4M | 10332 | 210481_s_at | 0.0270 | 0.7337 | |
| GSE53622 | CLEC4M | 10332 | 20760 | 0.1987 | 0.0209 | |
| GSE53624 | CLEC4M | 10332 | 20760 | 0.1533 | 0.1692 | |
| GSE63941 | CLEC4M | 10332 | 207995_s_at | 0.1173 | 0.2308 | |
| GSE77861 | CLEC4M | 10332 | 207995_s_at | -0.0671 | 0.6074 | |
| GSE97050 | CLEC4M | 10332 | A_24_P246196 | 0.2382 | 0.2705 | |
| TCGA | CLEC4M | 10332 | RNAseq | 0.7878 | 0.5664 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CLEC4M expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CLEC4M:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CLEC4M | 10332 | 4 | 3 | 23 | |
| GSE20123 | CLEC4M | 10332 | 3 | 2 | 25 | |
| GSE43470 | CLEC4M | 10332 | 2 | 6 | 35 | |
| GSE46452 | CLEC4M | 10332 | 47 | 1 | 11 | |
| GSE47630 | CLEC4M | 10332 | 5 | 7 | 28 | |
| GSE54993 | CLEC4M | 10332 | 16 | 3 | 51 | |
| GSE54994 | CLEC4M | 10332 | 6 | 13 | 34 | |
| GSE60625 | CLEC4M | 10332 | 9 | 0 | 2 | |
| GSE74703 | CLEC4M | 10332 | 2 | 4 | 30 | |
| GSE74704 | CLEC4M | 10332 | 0 | 2 | 18 | |
| TCGA | CLEC4M | 10332 | 9 | 20 | 67 |
Total number of gains: 103; Total number of losses: 61; Total Number of normals: 324.
Somatic mutations of CLEC4M:
Generating mutation plots.
Highly correlated genes for CLEC4M:
Showing top 20/743 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CLEC4M | AICDA | 0.728887 | 3 | 0 | 3 |
| CLEC4M | ABCC2 | 0.704441 | 3 | 0 | 3 |
| CLEC4M | FSTL4 | 0.685649 | 3 | 0 | 3 |
| CLEC4M | CA6 | 0.684798 | 4 | 0 | 4 |
| CLEC4M | KCNJ9 | 0.67709 | 4 | 0 | 4 |
| CLEC4M | OPTC | 0.671219 | 4 | 0 | 3 |
| CLEC4M | KRTAP3-1 | 0.669205 | 3 | 0 | 3 |
| CLEC4M | MYO15A | 0.666057 | 4 | 0 | 4 |
| CLEC4M | TTC9B | 0.664362 | 3 | 0 | 3 |
| CLEC4M | SPAM1 | 0.664281 | 4 | 0 | 4 |
| CLEC4M | KCNA4 | 0.662741 | 4 | 0 | 4 |
| CLEC4M | FAM163A | 0.659464 | 3 | 0 | 3 |
| CLEC4M | MEP1B | 0.659153 | 4 | 0 | 3 |
| CLEC4M | SI | 0.658357 | 5 | 0 | 5 |
| CLEC4M | SUN5 | 0.657805 | 4 | 0 | 3 |
| CLEC4M | LIF | 0.655149 | 3 | 0 | 3 |
| CLEC4M | S100G | 0.655026 | 3 | 0 | 3 |
| CLEC4M | BTBD17 | 0.654347 | 4 | 0 | 3 |
| CLEC4M | ADORA3 | 0.651812 | 3 | 0 | 3 |
| CLEC4M | FABP7 | 0.646557 | 4 | 0 | 4 |
For details and further investigation, click here
