SI

 

Full name: sucrase-isomaltase Alias Symbol: 
Type: protein-coding gene Cytoband: 3q26.1
Entrez ID: 6476 HGNC ID: HGNC:10856 Ensembl Gene: ENSG00000090402 OMIM ID: 609845
Drug and gene relationship at DGIdb

 

Expression of SI:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 SI 6476 206664_at 0.2257 0.4969
GSE20347 SI 6476 206664_at 0.0112 0.8293
GSE23400 SI 6476 206664_at -0.0236 0.1000
GSE26886 SI 6476 206664_at 0.0054 0.9537
GSE29001 SI 6476 206664_at -0.0136 0.9103
GSE38129 SI 6476 206664_at -0.0120 0.8607
GSE45670 SI 6476 206664_at 0.0214 0.7595
GSE53622 SI 6476 104829 0.0741 0.7727
GSE53624 SI 6476 104829 0.0929 0.5813
GSE63941 SI 6476 206664_at 0.0773 0.5290
GSE77861 SI 6476 206664_at 0.0535 0.4352
TCGA SI 6476 RNAseq 0.8630 0.6363

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by SI expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of SI:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 SI 6476 21 0 9
GSE20123 SI 6476 21 0 9
GSE43470 SI 6476 23 0 20
GSE46452 SI 6476 18 2 39
GSE47630 SI 6476 27 2 11
GSE54993 SI 6476 1 13 56
GSE54994 SI 6476 41 0 12
GSE60625 SI 6476 0 6 5
GSE74703 SI 6476 19 0 17
GSE74704 SI 6476 13 0 7
TCGA SI 6476 78 0 18

Total number of gains: 262; Total number of losses: 23; Total Number of normals: 203.  


 

Somatic mutations of SI:

 

Generating mutation plots.

 

Highly correlated genes for SI:

 

Showing top 20/173 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
SILINC002160.737907303
SIKRTAP9-90.714011303
SIC6orf150.707034404
SIC60.671659303
SICAMK40.669143303
SICLEC4M0.658357505
SISCG30.652544303
SISPTA10.640297404
SIGABRA50.63827303
SIKLC20.633737303
SIGFRA10.63297303
SINMNAT20.631332303
SIGYPA0.629443604
SISLC9A70.627309303
SIASB40.626373303
SISTRADA0.624622303
SIADPRH0.624265404
SIPVALB0.621563503
SIDGCR90.621111303
SICGA0.617957303

For details and further investigation, click here