| Full name: opticin | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1q32.1 | ||
| Entrez ID: 26254 | HGNC ID: HGNC:8158 | Ensembl Gene: ENSG00000188770 | OMIM ID: 605127 |
| Drug and gene relationship at DGIdb | |||
Expression of OPTC:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | OPTC | 26254 | 223884_at | -0.1996 | 0.4255 | |
| GSE26886 | OPTC | 26254 | 223884_at | -0.0039 | 0.9805 | |
| GSE45670 | OPTC | 26254 | 223884_at | 0.1730 | 0.0443 | |
| GSE53622 | OPTC | 26254 | 41941 | 0.0195 | 0.8902 | |
| GSE53624 | OPTC | 26254 | 41941 | 0.2920 | 0.0003 | |
| GSE63941 | OPTC | 26254 | 223884_at | 0.3508 | 0.0770 | |
| GSE77861 | OPTC | 26254 | 223884_at | -0.1448 | 0.3392 | |
| GSE97050 | OPTC | 26254 | A_23_P97096 | 0.1491 | 0.4717 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by OPTC expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of OPTC:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | OPTC | 26254 | 11 | 0 | 19 | |
| GSE20123 | OPTC | 26254 | 11 | 0 | 19 | |
| GSE43470 | OPTC | 26254 | 6 | 0 | 37 | |
| GSE46452 | OPTC | 26254 | 3 | 1 | 55 | |
| GSE47630 | OPTC | 26254 | 14 | 0 | 26 | |
| GSE54993 | OPTC | 26254 | 0 | 6 | 64 | |
| GSE54994 | OPTC | 26254 | 15 | 0 | 38 | |
| GSE60625 | OPTC | 26254 | 0 | 0 | 11 | |
| GSE74703 | OPTC | 26254 | 6 | 0 | 30 | |
| GSE74704 | OPTC | 26254 | 5 | 0 | 15 | |
| TCGA | OPTC | 26254 | 44 | 4 | 48 |
Total number of gains: 115; Total number of losses: 11; Total Number of normals: 362.
Somatic mutations of OPTC:
Generating mutation plots.
Highly correlated genes for OPTC:
Showing top 20/476 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| OPTC | F2RL3 | 0.787923 | 3 | 0 | 3 |
| OPTC | ANKRD33B | 0.780298 | 3 | 0 | 3 |
| OPTC | RASL10B | 0.775039 | 3 | 0 | 3 |
| OPTC | ZNF646 | 0.770589 | 3 | 0 | 3 |
| OPTC | LRIT1 | 0.762418 | 3 | 0 | 3 |
| OPTC | TMEM59L | 0.761311 | 3 | 0 | 3 |
| OPTC | RIIAD1 | 0.757003 | 3 | 0 | 3 |
| OPTC | DRGX | 0.751741 | 3 | 0 | 3 |
| OPTC | FAM71F1 | 0.751092 | 3 | 0 | 3 |
| OPTC | KCNH3 | 0.748765 | 4 | 0 | 4 |
| OPTC | C11orf86 | 0.748702 | 3 | 0 | 3 |
| OPTC | DOK7 | 0.746329 | 4 | 0 | 4 |
| OPTC | PTCRA | 0.742132 | 3 | 0 | 3 |
| OPTC | KIRREL2 | 0.738187 | 3 | 0 | 3 |
| OPTC | TAOK2 | 0.73545 | 3 | 0 | 3 |
| OPTC | KRTAP4-8 | 0.729313 | 4 | 0 | 4 |
| OPTC | ADH6 | 0.728985 | 4 | 0 | 4 |
| OPTC | CDK5R2 | 0.724272 | 4 | 0 | 4 |
| OPTC | DPYSL4 | 0.720271 | 3 | 0 | 3 |
| OPTC | SLC22A25 | 0.719073 | 4 | 0 | 3 |
For details and further investigation, click here
