| Full name: cyclin and CBS domain divalent metal cation transport mediator 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 10q24.32 | ||
| Entrez ID: 54805 | HGNC ID: HGNC:103 | Ensembl Gene: ENSG00000148842 | OMIM ID: 607803 |
| Drug and gene relationship at DGIdb | |||
Expression of CNNM2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CNNM2 | 54805 | 209874_x_at | 0.1805 | 0.6624 | |
| GSE20347 | CNNM2 | 54805 | 209874_x_at | 0.3717 | 0.0006 | |
| GSE23400 | CNNM2 | 54805 | 209874_x_at | -0.0128 | 0.7810 | |
| GSE26886 | CNNM2 | 54805 | 209874_x_at | 0.8945 | 0.0002 | |
| GSE29001 | CNNM2 | 54805 | 209874_x_at | 0.1122 | 0.5911 | |
| GSE38129 | CNNM2 | 54805 | 209874_x_at | 0.2273 | 0.0107 | |
| GSE45670 | CNNM2 | 54805 | 209874_x_at | 0.1798 | 0.0605 | |
| GSE53622 | CNNM2 | 54805 | 36961 | 0.3150 | 0.0288 | |
| GSE53624 | CNNM2 | 54805 | 36961 | 0.4689 | 0.0001 | |
| GSE63941 | CNNM2 | 54805 | 209874_x_at | -0.4331 | 0.0806 | |
| GSE77861 | CNNM2 | 54805 | 1554523_a_at | 0.1387 | 0.2141 | |
| GSE97050 | CNNM2 | 54805 | A_24_P93896 | -0.1045 | 0.7439 | |
| SRP007169 | CNNM2 | 54805 | RNAseq | 1.3469 | 0.0398 | |
| SRP008496 | CNNM2 | 54805 | RNAseq | 0.8870 | 0.0539 | |
| SRP064894 | CNNM2 | 54805 | RNAseq | 0.3945 | 0.0600 | |
| SRP133303 | CNNM2 | 54805 | RNAseq | 0.0149 | 0.9372 | |
| SRP159526 | CNNM2 | 54805 | RNAseq | 0.8170 | 0.0933 | |
| SRP193095 | CNNM2 | 54805 | RNAseq | 0.4339 | 0.0033 | |
| SRP219564 | CNNM2 | 54805 | RNAseq | 0.3295 | 0.3829 | |
| TCGA | CNNM2 | 54805 | RNAseq | -0.0873 | 0.1630 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by CNNM2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CNNM2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CNNM2 | 54805 | 2 | 9 | 19 | |
| GSE20123 | CNNM2 | 54805 | 2 | 8 | 20 | |
| GSE43470 | CNNM2 | 54805 | 0 | 8 | 35 | |
| GSE46452 | CNNM2 | 54805 | 0 | 11 | 48 | |
| GSE47630 | CNNM2 | 54805 | 2 | 14 | 24 | |
| GSE54993 | CNNM2 | 54805 | 8 | 0 | 62 | |
| GSE54994 | CNNM2 | 54805 | 1 | 11 | 41 | |
| GSE60625 | CNNM2 | 54805 | 0 | 0 | 11 | |
| GSE74703 | CNNM2 | 54805 | 0 | 5 | 31 | |
| GSE74704 | CNNM2 | 54805 | 1 | 4 | 15 | |
| TCGA | CNNM2 | 54805 | 5 | 30 | 61 |
Total number of gains: 21; Total number of losses: 100; Total Number of normals: 367.
Somatic mutations of CNNM2:
Generating mutation plots.
Highly correlated genes for CNNM2:
Showing top 20/254 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CNNM2 | TRDN | 0.69249 | 3 | 0 | 3 |
| CNNM2 | CITED1 | 0.678509 | 3 | 0 | 3 |
| CNNM2 | CIB2 | 0.668579 | 3 | 0 | 3 |
| CNNM2 | RAMP2 | 0.665344 | 3 | 0 | 3 |
| CNNM2 | CHGB | 0.664449 | 4 | 0 | 4 |
| CNNM2 | EDIL3 | 0.652063 | 3 | 0 | 3 |
| CNNM2 | ZNF703 | 0.645676 | 5 | 0 | 4 |
| CNNM2 | HMGN4 | 0.639931 | 3 | 0 | 3 |
| CNNM2 | ZNF599 | 0.639328 | 4 | 0 | 3 |
| CNNM2 | IFT172 | 0.637366 | 4 | 0 | 3 |
| CNNM2 | TIGD2 | 0.628574 | 3 | 0 | 3 |
| CNNM2 | DYNC1I1 | 0.61676 | 6 | 0 | 4 |
| CNNM2 | TSC22D1-AS1 | 0.615453 | 3 | 0 | 3 |
| CNNM2 | ARIH2OS | 0.609809 | 3 | 0 | 3 |
| CNNM2 | LNP1 | 0.609531 | 3 | 0 | 3 |
| CNNM2 | HNRNPLL | 0.60563 | 3 | 0 | 3 |
| CNNM2 | EXTL2 | 0.603437 | 6 | 0 | 5 |
| CNNM2 | ERICH1 | 0.602757 | 3 | 0 | 3 |
| CNNM2 | DYNC2H1 | 0.597632 | 3 | 0 | 3 |
| CNNM2 | ZNF45 | 0.597494 | 4 | 0 | 3 |
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