| Full name: calcium and integrin binding family member 2 | Alias Symbol: KIP2 | ||
| Type: protein-coding gene | Cytoband: 15q25.1 | ||
| Entrez ID: 10518 | HGNC ID: HGNC:24579 | Ensembl Gene: ENSG00000136425 | OMIM ID: 605564 |
| Drug and gene relationship at DGIdb | |||
Expression of CIB2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CIB2 | 10518 | 205008_s_at | 0.0702 | 0.9284 | |
| GSE20347 | CIB2 | 10518 | 205008_s_at | 0.1698 | 0.2697 | |
| GSE23400 | CIB2 | 10518 | 205008_s_at | -0.0784 | 0.1148 | |
| GSE26886 | CIB2 | 10518 | 205008_s_at | 0.8936 | 0.0004 | |
| GSE29001 | CIB2 | 10518 | 205008_s_at | 0.0523 | 0.8775 | |
| GSE38129 | CIB2 | 10518 | 205008_s_at | 0.2266 | 0.1650 | |
| GSE45670 | CIB2 | 10518 | 205008_s_at | 0.3363 | 0.0700 | |
| GSE53622 | CIB2 | 10518 | 89427 | 0.5469 | 0.0000 | |
| GSE53624 | CIB2 | 10518 | 89427 | 0.2229 | 0.0097 | |
| GSE63941 | CIB2 | 10518 | 205008_s_at | 0.1909 | 0.7162 | |
| GSE77861 | CIB2 | 10518 | 205008_s_at | 0.0473 | 0.6747 | |
| GSE97050 | CIB2 | 10518 | A_33_P3308914 | -0.3200 | 0.2390 | |
| SRP064894 | CIB2 | 10518 | RNAseq | 0.2109 | 0.5316 | |
| SRP133303 | CIB2 | 10518 | RNAseq | 0.9772 | 0.0046 | |
| SRP159526 | CIB2 | 10518 | RNAseq | 1.4413 | 0.0000 | |
| SRP219564 | CIB2 | 10518 | RNAseq | -0.5954 | 0.4661 | |
| TCGA | CIB2 | 10518 | RNAseq | 0.5430 | 0.0004 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by CIB2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CIB2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CIB2 | 10518 | 7 | 1 | 22 | |
| GSE20123 | CIB2 | 10518 | 7 | 1 | 22 | |
| GSE43470 | CIB2 | 10518 | 4 | 5 | 34 | |
| GSE46452 | CIB2 | 10518 | 3 | 7 | 49 | |
| GSE47630 | CIB2 | 10518 | 8 | 10 | 22 | |
| GSE54993 | CIB2 | 10518 | 5 | 6 | 59 | |
| GSE54994 | CIB2 | 10518 | 5 | 6 | 42 | |
| GSE60625 | CIB2 | 10518 | 4 | 0 | 7 | |
| GSE74703 | CIB2 | 10518 | 4 | 3 | 29 | |
| GSE74704 | CIB2 | 10518 | 3 | 1 | 16 | |
| TCGA | CIB2 | 10518 | 14 | 15 | 67 |
Total number of gains: 64; Total number of losses: 55; Total Number of normals: 369.
Somatic mutations of CIB2:
Generating mutation plots.
Highly correlated genes for CIB2:
Showing top 20/120 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CIB2 | TMEM174 | 0.67518 | 3 | 0 | 3 |
| CIB2 | IKBKG | 0.670117 | 3 | 0 | 3 |
| CIB2 | CNNM2 | 0.668579 | 3 | 0 | 3 |
| CIB2 | CDC42EP4 | 0.663878 | 3 | 0 | 3 |
| CIB2 | CITED1 | 0.651496 | 6 | 0 | 4 |
| CIB2 | PRTFDC1 | 0.648491 | 3 | 0 | 3 |
| CIB2 | NID1 | 0.643416 | 5 | 0 | 5 |
| CIB2 | MMD | 0.636546 | 5 | 0 | 4 |
| CIB2 | TTC7B | 0.630117 | 3 | 0 | 3 |
| CIB2 | ATP2B4 | 0.628672 | 3 | 0 | 3 |
| CIB2 | SOST | 0.623369 | 3 | 0 | 3 |
| CIB2 | NEURL2 | 0.620162 | 3 | 0 | 3 |
| CIB2 | GJC1 | 0.617754 | 5 | 0 | 4 |
| CIB2 | SLC39A13 | 0.617404 | 3 | 0 | 3 |
| CIB2 | EFEMP2 | 0.612266 | 5 | 0 | 4 |
| CIB2 | CD83 | 0.611226 | 3 | 0 | 3 |
| CIB2 | COL4A2 | 0.607031 | 6 | 0 | 5 |
| CIB2 | ZNF827 | 0.604285 | 3 | 0 | 3 |
| CIB2 | COL12A1 | 0.59229 | 4 | 0 | 3 |
| CIB2 | COL4A1 | 0.588615 | 5 | 0 | 4 |
For details and further investigation, click here
