| Full name: leukemia NUP98 fusion partner 1 | Alias Symbol: NP3 | ||
| Type: protein-coding gene | Cytoband: 3q12.2 | ||
| Entrez ID: 348801 | HGNC ID: HGNC:28014 | Ensembl Gene: ENSG00000206535 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of LNP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LNP1 | 348801 | 227181_at | 0.0876 | 0.8854 | |
| GSE26886 | LNP1 | 348801 | 227181_at | 0.8326 | 0.0002 | |
| GSE45670 | LNP1 | 348801 | 227181_at | -0.0143 | 0.9455 | |
| GSE63941 | LNP1 | 348801 | 227181_at | 0.0004 | 0.9996 | |
| GSE77861 | LNP1 | 348801 | 227181_at | 0.1038 | 0.6467 | |
| GSE97050 | LNP1 | 348801 | A_33_P3215739 | -0.0960 | 0.7123 | |
| SRP064894 | LNP1 | 348801 | RNAseq | 0.6227 | 0.0238 | |
| SRP133303 | LNP1 | 348801 | RNAseq | 0.7701 | 0.0059 | |
| SRP159526 | LNP1 | 348801 | RNAseq | 1.0154 | 0.0085 | |
| SRP219564 | LNP1 | 348801 | RNAseq | -0.2316 | 0.7590 | |
| TCGA | LNP1 | 348801 | RNAseq | 0.1249 | 0.4301 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by LNP1 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of LNP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LNP1 | 348801 | 17 | 1 | 12 | |
| GSE20123 | LNP1 | 348801 | 16 | 1 | 13 | |
| GSE43470 | LNP1 | 348801 | 19 | 1 | 23 | |
| GSE46452 | LNP1 | 348801 | 12 | 6 | 41 | |
| GSE47630 | LNP1 | 348801 | 16 | 6 | 18 | |
| GSE54993 | LNP1 | 348801 | 2 | 5 | 63 | |
| GSE54994 | LNP1 | 348801 | 27 | 5 | 21 | |
| GSE60625 | LNP1 | 348801 | 0 | 6 | 5 | |
| GSE74703 | LNP1 | 348801 | 15 | 1 | 20 | |
| GSE74704 | LNP1 | 348801 | 13 | 1 | 6 | |
| TCGA | LNP1 | 348801 | 48 | 10 | 38 |
Total number of gains: 185; Total number of losses: 43; Total Number of normals: 260.
Somatic mutations of LNP1:
Generating mutation plots.
Highly correlated genes for LNP1:
Showing top 20/357 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LNP1 | EIF3G | 0.829872 | 3 | 0 | 3 |
| LNP1 | PKIG | 0.81251 | 3 | 0 | 3 |
| LNP1 | STARD13 | 0.800346 | 3 | 0 | 3 |
| LNP1 | TLN2 | 0.773367 | 3 | 0 | 3 |
| LNP1 | NCAM1 | 0.772558 | 3 | 0 | 3 |
| LNP1 | UBXN10 | 0.765285 | 3 | 0 | 3 |
| LNP1 | KIAA1328 | 0.761852 | 3 | 0 | 3 |
| LNP1 | SCMH1 | 0.761631 | 4 | 0 | 4 |
| LNP1 | PDK3 | 0.75809 | 3 | 0 | 3 |
| LNP1 | HMCN1 | 0.756083 | 3 | 0 | 3 |
| LNP1 | SEMA3A | 0.750731 | 3 | 0 | 3 |
| LNP1 | GATC | 0.750193 | 3 | 0 | 3 |
| LNP1 | ANGPT1 | 0.747232 | 3 | 0 | 3 |
| LNP1 | LRPAP1 | 0.747136 | 3 | 0 | 3 |
| LNP1 | KCNMB4 | 0.744445 | 4 | 0 | 3 |
| LNP1 | LIN7A | 0.743262 | 3 | 0 | 3 |
| LNP1 | RFTN1 | 0.742925 | 3 | 0 | 3 |
| LNP1 | HCFC1 | 0.742459 | 3 | 0 | 3 |
| LNP1 | MACF1 | 0.740557 | 3 | 0 | 3 |
| LNP1 | TCEA2 | 0.739614 | 3 | 0 | 3 |
For details and further investigation, click here
