| Full name: receptor activity modifying protein 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 17q21.2 | ||
| Entrez ID: 10266 | HGNC ID: HGNC:9844 | Ensembl Gene: ENSG00000131477 | OMIM ID: 605154 |
| Drug and gene relationship at DGIdb | |||
RAMP2 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04270 | Vascular smooth muscle contraction |
Expression of RAMP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RAMP2 | 10266 | 205779_at | -0.1265 | 0.8516 | |
| GSE20347 | RAMP2 | 10266 | 205779_at | -0.1029 | 0.2855 | |
| GSE23400 | RAMP2 | 10266 | 205779_at | -0.1798 | 0.0000 | |
| GSE26886 | RAMP2 | 10266 | 205779_at | 0.0968 | 0.5843 | |
| GSE29001 | RAMP2 | 10266 | 205779_at | -0.1123 | 0.5572 | |
| GSE38129 | RAMP2 | 10266 | 205779_at | -0.4175 | 0.0074 | |
| GSE45670 | RAMP2 | 10266 | 205779_at | -0.1488 | 0.2341 | |
| GSE53622 | RAMP2 | 10266 | 158634 | -0.3610 | 0.0024 | |
| GSE53624 | RAMP2 | 10266 | 158634 | -0.3335 | 0.0603 | |
| GSE63941 | RAMP2 | 10266 | 205779_at | 0.2193 | 0.2747 | |
| GSE77861 | RAMP2 | 10266 | 205779_at | -0.0722 | 0.6853 | |
| GSE97050 | RAMP2 | 10266 | A_24_P116710 | 0.4316 | 0.3271 | |
| SRP007169 | RAMP2 | 10266 | RNAseq | 0.3630 | 0.4961 | |
| SRP008496 | RAMP2 | 10266 | RNAseq | 0.8719 | 0.0450 | |
| SRP064894 | RAMP2 | 10266 | RNAseq | 0.6937 | 0.1091 | |
| SRP133303 | RAMP2 | 10266 | RNAseq | -0.7739 | 0.0014 | |
| SRP159526 | RAMP2 | 10266 | RNAseq | -0.0895 | 0.7748 | |
| SRP193095 | RAMP2 | 10266 | RNAseq | 0.5279 | 0.0124 | |
| SRP219564 | RAMP2 | 10266 | RNAseq | 0.0900 | 0.8791 | |
| TCGA | RAMP2 | 10266 | RNAseq | -0.2498 | 0.0191 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RAMP2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RAMP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RAMP2 | 10266 | 6 | 2 | 22 | |
| GSE20123 | RAMP2 | 10266 | 6 | 2 | 22 | |
| GSE43470 | RAMP2 | 10266 | 1 | 2 | 40 | |
| GSE46452 | RAMP2 | 10266 | 34 | 0 | 25 | |
| GSE47630 | RAMP2 | 10266 | 8 | 1 | 31 | |
| GSE54993 | RAMP2 | 10266 | 3 | 4 | 63 | |
| GSE54994 | RAMP2 | 10266 | 8 | 5 | 40 | |
| GSE60625 | RAMP2 | 10266 | 4 | 0 | 7 | |
| GSE74703 | RAMP2 | 10266 | 1 | 1 | 34 | |
| GSE74704 | RAMP2 | 10266 | 4 | 1 | 15 | |
| TCGA | RAMP2 | 10266 | 23 | 6 | 67 |
Total number of gains: 98; Total number of losses: 24; Total Number of normals: 366.
Somatic mutations of RAMP2:
Generating mutation plots.
Highly correlated genes for RAMP2:
Showing top 20/563 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RAMP2 | AMZ1 | 0.72564 | 3 | 0 | 3 |
| RAMP2 | PTGER4 | 0.723539 | 3 | 0 | 3 |
| RAMP2 | BTN1A1 | 0.719801 | 4 | 0 | 4 |
| RAMP2 | NEDD9 | 0.719773 | 3 | 0 | 3 |
| RAMP2 | ST6GALNAC3 | 0.71855 | 4 | 0 | 4 |
| RAMP2 | NHLH1 | 0.716425 | 3 | 0 | 3 |
| RAMP2 | OR10H2 | 0.71484 | 3 | 0 | 3 |
| RAMP2 | ZNF512 | 0.699175 | 3 | 0 | 3 |
| RAMP2 | TEK | 0.694793 | 8 | 0 | 7 |
| RAMP2 | HAND1 | 0.687698 | 4 | 0 | 3 |
| RAMP2 | GIMAP5 | 0.682136 | 3 | 0 | 3 |
| RAMP2 | ECSCR | 0.67618 | 7 | 0 | 6 |
| RAMP2 | MAP4 | 0.673045 | 3 | 0 | 3 |
| RAMP2 | GIMAP1 | 0.672647 | 4 | 0 | 4 |
| RAMP2 | GALNT8 | 0.669803 | 4 | 0 | 3 |
| RAMP2 | PIK3R5 | 0.667226 | 3 | 0 | 3 |
| RAMP2 | RABEP2 | 0.666713 | 3 | 0 | 3 |
| RAMP2 | CNNM2 | 0.665344 | 3 | 0 | 3 |
| RAMP2 | SLC6A7 | 0.662042 | 3 | 0 | 3 |
| RAMP2 | CNTNAP1 | 0.657051 | 6 | 0 | 5 |
For details and further investigation, click here
