| Full name: ATP binding cassette subfamily A member 9 | Alias Symbol: EST640918 | ||
| Type: protein-coding gene | Cytoband: 17q24.2 | ||
| Entrez ID: 10350 | HGNC ID: HGNC:39 | Ensembl Gene: ENSG00000154258 | OMIM ID: 612507 |
| Drug and gene relationship at DGIdb | |||
Expression of ABCA9:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ABCA9 | 10350 | 242541_at | -1.4003 | 0.1720 | |
| GSE26886 | ABCA9 | 10350 | 242541_at | 0.0529 | 0.6753 | |
| GSE45670 | ABCA9 | 10350 | 242541_at | -1.4787 | 0.0000 | |
| GSE53622 | ABCA9 | 10350 | 135265 | 0.5262 | 0.0001 | |
| GSE53624 | ABCA9 | 10350 | 135265 | 0.4913 | 0.0000 | |
| GSE63941 | ABCA9 | 10350 | 242541_at | -1.0456 | 0.0003 | |
| GSE77861 | ABCA9 | 10350 | 242541_at | -0.0502 | 0.5281 | |
| GSE97050 | ABCA9 | 10350 | A_33_P3292179 | -0.1018 | 0.7392 | |
| SRP007169 | ABCA9 | 10350 | RNAseq | 0.8829 | 0.2303 | |
| SRP064894 | ABCA9 | 10350 | RNAseq | -0.6490 | 0.0900 | |
| SRP133303 | ABCA9 | 10350 | RNAseq | -0.7379 | 0.0331 | |
| SRP159526 | ABCA9 | 10350 | RNAseq | -0.7904 | 0.1129 | |
| SRP193095 | ABCA9 | 10350 | RNAseq | 0.1821 | 0.3013 | |
| SRP219564 | ABCA9 | 10350 | RNAseq | -0.3244 | 0.6655 | |
| TCGA | ABCA9 | 10350 | RNAseq | -1.4968 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by ABCA9 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ABCA9:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ABCA9 | 10350 | 3 | 1 | 26 | |
| GSE20123 | ABCA9 | 10350 | 3 | 1 | 26 | |
| GSE43470 | ABCA9 | 10350 | 6 | 0 | 37 | |
| GSE46452 | ABCA9 | 10350 | 31 | 1 | 27 | |
| GSE47630 | ABCA9 | 10350 | 7 | 1 | 32 | |
| GSE54993 | ABCA9 | 10350 | 2 | 5 | 63 | |
| GSE54994 | ABCA9 | 10350 | 9 | 4 | 40 | |
| GSE60625 | ABCA9 | 10350 | 4 | 3 | 4 | |
| GSE74703 | ABCA9 | 10350 | 6 | 0 | 30 | |
| GSE74704 | ABCA9 | 10350 | 3 | 1 | 16 | |
| TCGA | ABCA9 | 10350 | 30 | 10 | 56 |
Total number of gains: 104; Total number of losses: 27; Total Number of normals: 357.
Somatic mutations of ABCA9:
Generating mutation plots.
Highly correlated genes for ABCA9:
Showing top 20/136 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ABCA9 | OMD | 0.857102 | 3 | 0 | 3 |
| ABCA9 | SLIT3 | 0.856077 | 3 | 0 | 3 |
| ABCA9 | CNTN4 | 0.838252 | 3 | 0 | 3 |
| ABCA9 | GYPC | 0.814814 | 3 | 0 | 3 |
| ABCA9 | PTGIS | 0.812059 | 3 | 0 | 3 |
| ABCA9 | FABP3 | 0.811193 | 3 | 0 | 3 |
| ABCA9 | DACT3 | 0.810067 | 3 | 0 | 3 |
| ABCA9 | USP2-AS1 | 0.798026 | 3 | 0 | 3 |
| ABCA9 | KCNQ1OT1 | 0.773535 | 3 | 0 | 3 |
| ABCA9 | TMEM178A | 0.760001 | 3 | 0 | 3 |
| ABCA9 | MAGI2-AS3 | 0.758529 | 3 | 0 | 3 |
| ABCA9 | RSPO3 | 0.747552 | 3 | 0 | 3 |
| ABCA9 | ZCCHC24 | 0.744863 | 3 | 0 | 3 |
| ABCA9 | CNGA3 | 0.742335 | 3 | 0 | 3 |
| ABCA9 | HTR2A | 0.741081 | 3 | 0 | 3 |
| ABCA9 | PBX3 | 0.740925 | 3 | 0 | 3 |
| ABCA9 | SGCD | 0.736831 | 3 | 0 | 3 |
| ABCA9 | ZNF667 | 0.735327 | 6 | 0 | 6 |
| ABCA9 | LMOD1 | 0.72342 | 3 | 0 | 3 |
| ABCA9 | FBXL7 | 0.719536 | 3 | 0 | 3 |
For details and further investigation, click here
