| Full name: transmembrane protein 100 | Alias Symbol: FLJ10970|FLJ37856 | ||
| Type: protein-coding gene | Cytoband: 17q23.1 | ||
| Entrez ID: 55273 | HGNC ID: HGNC:25607 | Ensembl Gene: ENSG00000166292 | OMIM ID: 616334 |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM100:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM100 | 55273 | 219230_at | -1.9761 | 0.0672 | |
| GSE20347 | TMEM100 | 55273 | 219230_at | -0.8560 | 0.0004 | |
| GSE23400 | TMEM100 | 55273 | 219230_at | -0.4410 | 0.0000 | |
| GSE26886 | TMEM100 | 55273 | 219230_at | -0.4891 | 0.1234 | |
| GSE29001 | TMEM100 | 55273 | 219230_at | -1.1371 | 0.0062 | |
| GSE38129 | TMEM100 | 55273 | 219230_at | -1.8676 | 0.0000 | |
| GSE45670 | TMEM100 | 55273 | 219230_at | -2.9112 | 0.0000 | |
| GSE53622 | TMEM100 | 55273 | 113998 | -2.5731 | 0.0000 | |
| GSE53624 | TMEM100 | 55273 | 113998 | -2.8530 | 0.0000 | |
| GSE63941 | TMEM100 | 55273 | 219230_at | -4.8923 | 0.0000 | |
| GSE77861 | TMEM100 | 55273 | 219230_at | -0.0815 | 0.2309 | |
| GSE97050 | TMEM100 | 55273 | A_23_P15450 | -0.3707 | 0.2893 | |
| SRP064894 | TMEM100 | 55273 | RNAseq | -1.0010 | 0.0514 | |
| SRP133303 | TMEM100 | 55273 | RNAseq | -2.4527 | 0.0000 | |
| SRP159526 | TMEM100 | 55273 | RNAseq | -1.4424 | 0.0018 | |
| SRP219564 | TMEM100 | 55273 | RNAseq | 0.5565 | 0.5750 | |
| TCGA | TMEM100 | 55273 | RNAseq | -2.4943 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 9.
Survival by TMEM100 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM100:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM100 | 55273 | 4 | 1 | 25 | |
| GSE20123 | TMEM100 | 55273 | 4 | 1 | 25 | |
| GSE43470 | TMEM100 | 55273 | 2 | 1 | 40 | |
| GSE46452 | TMEM100 | 55273 | 32 | 0 | 27 | |
| GSE47630 | TMEM100 | 55273 | 7 | 1 | 32 | |
| GSE54993 | TMEM100 | 55273 | 2 | 4 | 64 | |
| GSE54994 | TMEM100 | 55273 | 9 | 5 | 39 | |
| GSE60625 | TMEM100 | 55273 | 4 | 0 | 7 | |
| GSE74703 | TMEM100 | 55273 | 2 | 1 | 33 | |
| GSE74704 | TMEM100 | 55273 | 3 | 1 | 16 | |
| TCGA | TMEM100 | 55273 | 26 | 7 | 63 |
Total number of gains: 95; Total number of losses: 22; Total Number of normals: 371.
Somatic mutations of TMEM100:
Generating mutation plots.
Highly correlated genes for TMEM100:
Showing top 20/1157 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM100 | PGM5-AS1 | 0.886639 | 3 | 0 | 3 |
| TMEM100 | ABCA8 | 0.881564 | 10 | 0 | 10 |
| TMEM100 | LINC01082 | 0.878233 | 5 | 0 | 5 |
| TMEM100 | SLC4A4 | 0.866841 | 5 | 0 | 5 |
| TMEM100 | PLCXD3 | 0.862151 | 4 | 0 | 4 |
| TMEM100 | RCAN2 | 0.836687 | 10 | 0 | 10 |
| TMEM100 | RSPO2 | 0.835213 | 3 | 0 | 3 |
| TMEM100 | PREX2 | 0.829913 | 3 | 0 | 3 |
| TMEM100 | ASPA | 0.826713 | 10 | 0 | 10 |
| TMEM100 | MAGI2-AS3 | 0.824343 | 5 | 0 | 5 |
| TMEM100 | FENDRR | 0.821593 | 5 | 0 | 5 |
| TMEM100 | GFRA1 | 0.82069 | 6 | 0 | 6 |
| TMEM100 | TCF21 | 0.817905 | 10 | 0 | 9 |
| TMEM100 | XKR4 | 0.815216 | 4 | 0 | 4 |
| TMEM100 | PLAC9 | 0.813896 | 4 | 0 | 4 |
| TMEM100 | SHISA3 | 0.803659 | 6 | 0 | 6 |
| TMEM100 | CXCL12 | 0.797776 | 10 | 0 | 10 |
| TMEM100 | RSPO1 | 0.796501 | 5 | 0 | 5 |
| TMEM100 | ANGPTL1 | 0.794941 | 6 | 0 | 6 |
| TMEM100 | ADH1B | 0.793647 | 10 | 0 | 9 |
For details and further investigation, click here
