| Full name: glutathione S-transferase mu 5 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1p13.3 | ||
| Entrez ID: 2949 | HGNC ID: HGNC:4637 | Ensembl Gene: ENSG00000134201 | OMIM ID: 138385 |
| Drug and gene relationship at DGIdb | |||
Expression of GSTM5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GSTM5 | 2949 | 205752_s_at | -0.9864 | 0.0375 | |
| GSE20347 | GSTM5 | 2949 | 205752_s_at | -0.2649 | 0.1036 | |
| GSE23400 | GSTM5 | 2949 | 205752_s_at | -0.3998 | 0.0044 | |
| GSE26886 | GSTM5 | 2949 | 205752_s_at | 0.0753 | 0.7723 | |
| GSE29001 | GSTM5 | 2949 | 205752_s_at | -0.6130 | 0.0050 | |
| GSE38129 | GSTM5 | 2949 | 205752_s_at | -0.8439 | 0.0001 | |
| GSE45670 | GSTM5 | 2949 | 205752_s_at | -1.1857 | 0.0000 | |
| GSE53622 | GSTM5 | 2949 | 42105 | -0.5450 | 0.0000 | |
| GSE53624 | GSTM5 | 2949 | 42105 | -0.6327 | 0.0000 | |
| GSE63941 | GSTM5 | 2949 | 205752_s_at | -1.2407 | 0.0000 | |
| GSE77861 | GSTM5 | 2949 | 205752_s_at | -0.1148 | 0.5271 | |
| GSE97050 | GSTM5 | 2949 | A_23_P97606 | -0.2038 | 0.5068 | |
| SRP064894 | GSTM5 | 2949 | RNAseq | -2.7175 | 0.0000 | |
| SRP133303 | GSTM5 | 2949 | RNAseq | -2.9239 | 0.0000 | |
| SRP159526 | GSTM5 | 2949 | RNAseq | -2.0618 | 0.0000 | |
| SRP219564 | GSTM5 | 2949 | RNAseq | -0.9411 | 0.4290 | |
| TCGA | GSTM5 | 2949 | RNAseq | -1.6844 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 6.
Survival by GSTM5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GSTM5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GSTM5 | 2949 | 0 | 12 | 18 | |
| GSE20123 | GSTM5 | 2949 | 0 | 11 | 19 | |
| GSE43470 | GSTM5 | 2949 | 0 | 9 | 34 | |
| GSE46452 | GSTM5 | 2949 | 2 | 1 | 56 | |
| GSE47630 | GSTM5 | 2949 | 9 | 5 | 26 | |
| GSE54993 | GSTM5 | 2949 | 0 | 1 | 69 | |
| GSE54994 | GSTM5 | 2949 | 7 | 4 | 42 | |
| GSE60625 | GSTM5 | 2949 | 0 | 0 | 11 | |
| GSE74703 | GSTM5 | 2949 | 0 | 7 | 29 | |
| GSE74704 | GSTM5 | 2949 | 0 | 7 | 13 | |
| TCGA | GSTM5 | 2949 | 9 | 26 | 61 |
Total number of gains: 27; Total number of losses: 83; Total Number of normals: 378.
Somatic mutations of GSTM5:
Generating mutation plots.
Highly correlated genes for GSTM5:
Showing top 20/581 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GSTM5 | PGM5-AS1 | 0.848833 | 3 | 0 | 3 |
| GSTM5 | PABPC5 | 0.794951 | 3 | 0 | 3 |
| GSTM5 | LAMA2 | 0.769718 | 6 | 0 | 6 |
| GSTM5 | LINC00968 | 0.759865 | 4 | 0 | 3 |
| GSTM5 | RASGRF2 | 0.756865 | 4 | 0 | 4 |
| GSTM5 | MYO1A | 0.745202 | 4 | 0 | 4 |
| GSTM5 | ZMYND10 | 0.743874 | 3 | 0 | 3 |
| GSTM5 | CNTN4 | 0.743867 | 6 | 0 | 5 |
| GSTM5 | SHROOM1 | 0.742981 | 3 | 0 | 3 |
| GSTM5 | NEGR1 | 0.74088 | 6 | 0 | 5 |
| GSTM5 | TBX5-AS1 | 0.733131 | 4 | 0 | 3 |
| GSTM5 | ANKRD33 | 0.729504 | 3 | 0 | 3 |
| GSTM5 | KCNMB2 | 0.729128 | 4 | 0 | 4 |
| GSTM5 | RNF150 | 0.728058 | 5 | 0 | 5 |
| GSTM5 | TUBA8 | 0.727876 | 4 | 0 | 4 |
| GSTM5 | MAP2 | 0.724616 | 3 | 0 | 3 |
| GSTM5 | WDFY3-AS2 | 0.72063 | 4 | 0 | 4 |
| GSTM5 | CCBE1 | 0.719282 | 3 | 0 | 3 |
| GSTM5 | LINC01279 | 0.71829 | 4 | 0 | 4 |
| GSTM5 | CADPS | 0.718258 | 6 | 0 | 6 |
For details and further investigation, click here
