COLCA2

 

Full name: colorectal cancer associated 2 Alias Symbol: CASC13
Type: protein-coding gene Cytoband: 11q23.1
Entrez ID: 120376 HGNC ID: HGNC:26978 Ensembl Gene: ENSG00000214290 OMIM ID: 615694
Drug and gene relationship at DGIdb

 

Expression of COLCA2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 COLCA2 120376 228338_at -0.4007 0.6951
GSE26886 COLCA2 120376 228338_at -0.2234 0.7661
GSE45670 COLCA2 120376 228338_at 0.0167 0.9784
GSE53622 COLCA2 120376 28092 -0.4626 0.1047
GSE53624 COLCA2 120376 28092 -0.4261 0.0406
GSE63941 COLCA2 120376 228338_at 2.1876 0.2630
GSE77861 COLCA2 120376 228338_at 0.1538 0.8019
SRP064894 COLCA2 120376 RNAseq 0.5849 0.2115
SRP133303 COLCA2 120376 RNAseq -0.3079 0.4507
SRP193095 COLCA2 120376 RNAseq -0.1685 0.6338
SRP219564 COLCA2 120376 RNAseq 1.0899 0.1639

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by COLCA2 expression:

 

GSE53622GSE53624

 

Note: Click image to view full size file.  


Copy number change of COLCA2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 COLCA2 120376 0 12 18
GSE20123 COLCA2 120376 0 12 18
GSE43470 COLCA2 120376 2 6 35
GSE46452 COLCA2 120376 3 26 30
GSE47630 COLCA2 120376 2 19 19
GSE54993 COLCA2 120376 10 0 60
GSE54994 COLCA2 120376 5 19 29
GSE60625 COLCA2 120376 0 3 8
GSE74703 COLCA2 120376 1 4 31
GSE74704 COLCA2 120376 0 8 12

Total number of gains: 23; Total number of losses: 109; Total Number of normals: 260.  


 

Somatic mutations of COLCA2:

 

Generating mutation plots.

 

Highly correlated genes for COLCA2:

 

Showing top 20/37 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
COLCA2ZBED50.695294303
COLCA2RASSF60.683599303
COLCA2BET1L0.600268303
COLCA2TSPAN30.588618403
COLCA2TMEM620.583925403
COLCA2SCNN1A0.583444303
COLCA2MECOM0.580758604
COLCA2ANXA110.580265303
COLCA2TRIM680.580122503
COLCA2ALDH1A10.578083403
COLCA2ILDR10.574022403
COLCA2LDOC10.573701403
COLCA2GCNT20.56583604
COLCA2KIAA16710.563202403
COLCA2LINC010030.561577403
COLCA2MPPED20.561409303
COLCA2PLXNA20.560948303
COLCA2C11orf10.560587303
COLCA2CLDN80.558378704
COLCA2EPHX10.554591604

For details and further investigation, click here