TRIM68

 

Full name: tripartite motif containing 68 Alias Symbol: SS-56|FLJ10369
Type: protein-coding gene Cytoband: 11p15.4
Entrez ID: 55128 HGNC ID: HGNC:21161 Ensembl Gene: ENSG00000167333 OMIM ID: 613184
Drug and gene relationship at DGIdb

 

Expression of TRIM68:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TRIM68 55128 219405_at -0.2576 0.6029
GSE20347 TRIM68 55128 219405_at 0.1930 0.2279
GSE23400 TRIM68 55128 219405_at 0.1947 0.0019
GSE26886 TRIM68 55128 219405_at 0.3048 0.4099
GSE29001 TRIM68 55128 219405_at 0.3012 0.2144
GSE38129 TRIM68 55128 219405_at -0.0400 0.8458
GSE45670 TRIM68 55128 219405_at 0.1343 0.4007
GSE53622 TRIM68 55128 59042 -0.2393 0.0511
GSE53624 TRIM68 55128 59042 0.2006 0.0476
GSE63941 TRIM68 55128 219405_at -0.6946 0.2772
GSE77861 TRIM68 55128 219405_at 0.0214 0.9413
GSE97050 TRIM68 55128 A_23_P2097 0.0705 0.8017
SRP007169 TRIM68 55128 RNAseq 0.1251 0.7835
SRP008496 TRIM68 55128 RNAseq 0.6796 0.0402
SRP064894 TRIM68 55128 RNAseq 0.1550 0.3065
SRP133303 TRIM68 55128 RNAseq 0.0768 0.5950
SRP159526 TRIM68 55128 RNAseq -0.1482 0.6924
SRP193095 TRIM68 55128 RNAseq -0.1440 0.2796
SRP219564 TRIM68 55128 RNAseq -0.1108 0.7686
TCGA TRIM68 55128 RNAseq -0.3196 0.0000

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by TRIM68 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of TRIM68:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TRIM68 55128 1 12 17
GSE20123 TRIM68 55128 1 12 17
GSE43470 TRIM68 55128 1 8 34
GSE46452 TRIM68 55128 7 8 44
GSE47630 TRIM68 55128 3 13 24
GSE54993 TRIM68 55128 3 1 66
GSE54994 TRIM68 55128 1 13 39
GSE60625 TRIM68 55128 0 0 11
GSE74703 TRIM68 55128 1 6 29
GSE74704 TRIM68 55128 0 8 12
TCGA TRIM68 55128 8 39 49

Total number of gains: 26; Total number of losses: 120; Total Number of normals: 342.  


 

Somatic mutations of TRIM68:

 

Generating mutation plots.

 

Highly correlated genes for TRIM68:

 

Showing top 20/341 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TRIM68KAT50.762741303
TRIM68ASB80.747989303
TRIM68CCDC970.709732303
TRIM68GLUD10.699628303
TRIM68PUS7L0.698028303
TRIM68SRSF80.695491303
TRIM68HIP10.682815303
TRIM68ZBED50.681245705
TRIM68NCOR10.675768303
TRIM68PNN0.675071303
TRIM68SYT170.671494303
TRIM68ZNF7400.671491303
TRIM68NHS0.670747303
TRIM68LRRK10.670704303
TRIM68OSCP10.670548403
TRIM68ZNF6270.669493303
TRIM68KLHL150.667662303
TRIM68DNALI10.662999303
TRIM68ZNF3430.662544303
TRIM68FAM102B0.662514303

For details and further investigation, click here