| Full name: metallophosphoesterase domain containing 2 | Alias Symbol: 239FB|D11S302E|Hs.46638|FAM1B|dJ873F21.1|dJ1024C24.1 | ||
| Type: protein-coding gene | Cytoband: 11p14.1 | ||
| Entrez ID: 744 | HGNC ID: HGNC:1180 | Ensembl Gene: ENSG00000066382 | OMIM ID: 600911 |
| Drug and gene relationship at DGIdb | |||
Expression of MPPED2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MPPED2 | 744 | 205413_at | 0.4295 | 0.7360 | |
| GSE20347 | MPPED2 | 744 | 205413_at | -0.2454 | 0.3692 | |
| GSE23400 | MPPED2 | 744 | 215692_s_at | 0.0465 | 0.1595 | |
| GSE26886 | MPPED2 | 744 | 205413_at | -0.1290 | 0.9019 | |
| GSE29001 | MPPED2 | 744 | 205413_at | -0.2535 | 0.7210 | |
| GSE38129 | MPPED2 | 744 | 205413_at | -0.4886 | 0.1710 | |
| GSE45670 | MPPED2 | 744 | 205413_at | -0.7437 | 0.2845 | |
| GSE53622 | MPPED2 | 744 | 91403 | 0.2943 | 0.0719 | |
| GSE53624 | MPPED2 | 744 | 91403 | 0.2754 | 0.0328 | |
| GSE63941 | MPPED2 | 744 | 205413_at | 2.3838 | 0.2234 | |
| GSE77861 | MPPED2 | 744 | 215692_s_at | 0.0069 | 0.9668 | |
| GSE97050 | MPPED2 | 744 | A_32_P105825 | -0.4665 | 0.1819 | |
| SRP064894 | MPPED2 | 744 | RNAseq | -0.2576 | 0.4678 | |
| SRP133303 | MPPED2 | 744 | RNAseq | -0.9219 | 0.0002 | |
| SRP159526 | MPPED2 | 744 | RNAseq | 1.3478 | 0.0088 | |
| SRP193095 | MPPED2 | 744 | RNAseq | -0.1439 | 0.5629 | |
| SRP219564 | MPPED2 | 744 | RNAseq | -0.6334 | 0.4395 | |
| TCGA | MPPED2 | 744 | RNAseq | 0.2422 | 0.5187 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by MPPED2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MPPED2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MPPED2 | 744 | 1 | 9 | 20 | |
| GSE20123 | MPPED2 | 744 | 1 | 8 | 21 | |
| GSE43470 | MPPED2 | 744 | 2 | 4 | 37 | |
| GSE46452 | MPPED2 | 744 | 8 | 5 | 46 | |
| GSE47630 | MPPED2 | 744 | 3 | 10 | 27 | |
| GSE54993 | MPPED2 | 744 | 3 | 0 | 67 | |
| GSE54994 | MPPED2 | 744 | 4 | 10 | 39 | |
| GSE60625 | MPPED2 | 744 | 0 | 0 | 11 | |
| GSE74703 | MPPED2 | 744 | 2 | 2 | 32 | |
| GSE74704 | MPPED2 | 744 | 0 | 7 | 13 | |
| TCGA | MPPED2 | 744 | 12 | 25 | 59 |
Total number of gains: 36; Total number of losses: 80; Total Number of normals: 372.
Somatic mutations of MPPED2:
Generating mutation plots.
Highly correlated genes for MPPED2:
Showing top 20/112 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MPPED2 | KLHL15 | 0.740389 | 3 | 0 | 3 |
| MPPED2 | SETMAR | 0.73998 | 3 | 0 | 3 |
| MPPED2 | ACAP2 | 0.738648 | 3 | 0 | 3 |
| MPPED2 | CCIN | 0.734549 | 3 | 0 | 3 |
| MPPED2 | OR2T33 | 0.731304 | 3 | 0 | 3 |
| MPPED2 | SF1 | 0.729144 | 3 | 0 | 3 |
| MPPED2 | FAN1 | 0.718125 | 4 | 0 | 3 |
| MPPED2 | SPEG | 0.712367 | 3 | 0 | 3 |
| MPPED2 | SQSTM1 | 0.708511 | 3 | 0 | 3 |
| MPPED2 | ALG11 | 0.702905 | 3 | 0 | 3 |
| MPPED2 | FYTTD1 | 0.70232 | 3 | 0 | 3 |
| MPPED2 | RTN4IP1 | 0.70137 | 3 | 0 | 3 |
| MPPED2 | RRAGB | 0.696687 | 4 | 0 | 4 |
| MPPED2 | NES | 0.68068 | 3 | 0 | 3 |
| MPPED2 | FGF2 | 0.677935 | 3 | 0 | 3 |
| MPPED2 | HNRNPUL2 | 0.677757 | 3 | 0 | 3 |
| MPPED2 | DNAJC19 | 0.677756 | 4 | 0 | 3 |
| MPPED2 | OR2AT4 | 0.673035 | 3 | 0 | 3 |
| MPPED2 | C6orf120 | 0.672583 | 4 | 0 | 3 |
| MPPED2 | ZNRF3 | 0.671512 | 4 | 0 | 3 |
For details and further investigation, click here
