| Full name: glucosaminyl (N-acetyl) transferase 2 (I blood group) | Alias Symbol: IGNT|NAGCT1|bA421M1.1|bA360O19.2|ULG3 | ||
| Type: protein-coding gene | Cytoband: 6p24.3-p24.2 | ||
| Entrez ID: 2651 | HGNC ID: HGNC:4204 | Ensembl Gene: ENSG00000111846 | OMIM ID: 600429 |
| Drug and gene relationship at DGIdb | |||
Expression of GCNT2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GCNT2 | 2651 | 230788_at | -0.3847 | 0.7648 | |
| GSE20347 | GCNT2 | 2651 | 211020_at | -0.0490 | 0.3947 | |
| GSE23400 | GCNT2 | 2651 | 211020_at | -0.0507 | 0.1975 | |
| GSE26886 | GCNT2 | 2651 | 230788_at | -0.0455 | 0.9549 | |
| GSE29001 | GCNT2 | 2651 | 211020_at | -0.0308 | 0.8152 | |
| GSE38129 | GCNT2 | 2651 | 211020_at | -0.0918 | 0.0999 | |
| GSE45670 | GCNT2 | 2651 | 230788_at | 0.2080 | 0.7335 | |
| GSE53622 | GCNT2 | 2651 | 31697 | -0.4322 | 0.0344 | |
| GSE53624 | GCNT2 | 2651 | 72091 | -0.2623 | 0.1091 | |
| GSE63941 | GCNT2 | 2651 | 230788_at | 1.5751 | 0.2101 | |
| GSE77861 | GCNT2 | 2651 | 230788_at | 0.2019 | 0.6833 | |
| GSE97050 | GCNT2 | 2651 | A_33_P3411204 | -0.6899 | 0.1566 | |
| SRP007169 | GCNT2 | 2651 | RNAseq | 1.7458 | 0.0218 | |
| SRP064894 | GCNT2 | 2651 | RNAseq | -0.6197 | 0.0420 | |
| SRP133303 | GCNT2 | 2651 | RNAseq | 0.4029 | 0.4856 | |
| SRP159526 | GCNT2 | 2651 | RNAseq | 1.6845 | 0.0000 | |
| SRP193095 | GCNT2 | 2651 | RNAseq | -0.3451 | 0.2176 | |
| SRP219564 | GCNT2 | 2651 | RNAseq | -1.0522 | 0.0442 | |
| TCGA | GCNT2 | 2651 | RNAseq | -0.7216 | 0.0006 |
Upregulated datasets: 2; Downregulated datasets: 1.
Survival by GCNT2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GCNT2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GCNT2 | 2651 | 4 | 7 | 19 | |
| GSE20123 | GCNT2 | 2651 | 4 | 7 | 19 | |
| GSE43470 | GCNT2 | 2651 | 8 | 2 | 33 | |
| GSE46452 | GCNT2 | 2651 | 1 | 10 | 48 | |
| GSE47630 | GCNT2 | 2651 | 7 | 8 | 25 | |
| GSE54993 | GCNT2 | 2651 | 1 | 1 | 68 | |
| GSE54994 | GCNT2 | 2651 | 10 | 3 | 40 | |
| GSE60625 | GCNT2 | 2651 | 0 | 1 | 10 | |
| GSE74703 | GCNT2 | 2651 | 7 | 2 | 27 | |
| GSE74704 | GCNT2 | 2651 | 2 | 3 | 15 | |
| TCGA | GCNT2 | 2651 | 15 | 28 | 53 |
Total number of gains: 59; Total number of losses: 72; Total Number of normals: 357.
Somatic mutations of GCNT2:
Generating mutation plots.
Highly correlated genes for GCNT2:
Showing top 20/171 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GCNT2 | KCNK17 | 0.771354 | 3 | 0 | 3 |
| GCNT2 | SRP68 | 0.724665 | 3 | 0 | 3 |
| GCNT2 | CXCR1 | 0.715993 | 3 | 0 | 3 |
| GCNT2 | CXCR5 | 0.699417 | 3 | 0 | 3 |
| GCNT2 | CTPS2 | 0.674465 | 3 | 0 | 3 |
| GCNT2 | TMEM187 | 0.668035 | 4 | 0 | 4 |
| GCNT2 | TCTEX1D2 | 0.661744 | 4 | 0 | 3 |
| GCNT2 | ING3 | 0.65103 | 4 | 0 | 4 |
| GCNT2 | CBX7 | 0.649284 | 4 | 0 | 3 |
| GCNT2 | RAB4B | 0.644139 | 3 | 0 | 3 |
| GCNT2 | KCNE3 | 0.641019 | 4 | 0 | 3 |
| GCNT2 | NCBP1 | 0.640044 | 3 | 0 | 3 |
| GCNT2 | ID2 | 0.639812 | 4 | 0 | 3 |
| GCNT2 | MSI2 | 0.636025 | 5 | 0 | 3 |
| GCNT2 | LDOC1 | 0.631815 | 4 | 0 | 3 |
| GCNT2 | KAT6B | 0.630807 | 5 | 0 | 3 |
| GCNT2 | GBF1 | 0.630301 | 3 | 0 | 3 |
| GCNT2 | TBL1X | 0.628088 | 4 | 0 | 3 |
| GCNT2 | SPPL2A | 0.624031 | 4 | 0 | 3 |
| GCNT2 | RAB3D | 0.623558 | 3 | 0 | 3 |
For details and further investigation, click here
