| Full name: Ras association domain family member 6 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 4q13.3 | ||
| Entrez ID: 166824 | HGNC ID: HGNC:20796 | Ensembl Gene: ENSG00000169435 | OMIM ID: 612620 |
| Drug and gene relationship at DGIdb | |||
RASSF6 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04390 | Hippo signaling pathway |
Expression of RASSF6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RASSF6 | 166824 | 229147_at | 0.1019 | 0.9361 | |
| GSE26886 | RASSF6 | 166824 | 229147_at | 0.2633 | 0.6753 | |
| GSE45670 | RASSF6 | 166824 | 229147_at | 0.0906 | 0.8520 | |
| GSE63941 | RASSF6 | 166824 | 229147_at | 2.3680 | 0.0385 | |
| GSE77861 | RASSF6 | 166824 | 229147_at | -0.6348 | 0.3374 | |
| GSE97050 | RASSF6 | 166824 | A_33_P3235420 | 0.0817 | 0.7252 | |
| SRP007169 | RASSF6 | 166824 | RNAseq | -0.7934 | 0.2393 | |
| SRP064894 | RASSF6 | 166824 | RNAseq | -0.5933 | 0.1124 | |
| SRP133303 | RASSF6 | 166824 | RNAseq | 0.4961 | 0.1430 | |
| SRP159526 | RASSF6 | 166824 | RNAseq | -0.2090 | 0.6938 | |
| SRP193095 | RASSF6 | 166824 | RNAseq | -1.1185 | 0.0050 | |
| SRP219564 | RASSF6 | 166824 | RNAseq | 0.6300 | 0.5229 | |
| TCGA | RASSF6 | 166824 | RNAseq | -0.8351 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by RASSF6 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of RASSF6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RASSF6 | 166824 | 2 | 9 | 19 | |
| GSE20123 | RASSF6 | 166824 | 2 | 9 | 19 | |
| GSE43470 | RASSF6 | 166824 | 0 | 13 | 30 | |
| GSE46452 | RASSF6 | 166824 | 3 | 34 | 22 | |
| GSE47630 | RASSF6 | 166824 | 1 | 19 | 20 | |
| GSE54993 | RASSF6 | 166824 | 7 | 0 | 63 | |
| GSE54994 | RASSF6 | 166824 | 1 | 9 | 43 | |
| GSE60625 | RASSF6 | 166824 | 0 | 0 | 11 | |
| GSE74703 | RASSF6 | 166824 | 0 | 11 | 25 | |
| GSE74704 | RASSF6 | 166824 | 2 | 5 | 13 | |
| TCGA | RASSF6 | 166824 | 19 | 27 | 50 |
Total number of gains: 37; Total number of losses: 136; Total Number of normals: 315.
Somatic mutations of RASSF6:
Generating mutation plots.
Highly correlated genes for RASSF6:
Showing top 20/36 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RASSF6 | GRIPAP1 | 0.829686 | 3 | 0 | 3 |
| RASSF6 | SULT1A1 | 0.765504 | 3 | 0 | 3 |
| RASSF6 | NICN1 | 0.753235 | 3 | 0 | 3 |
| RASSF6 | MRPS16 | 0.713488 | 3 | 0 | 3 |
| RASSF6 | WDR74 | 0.69985 | 3 | 0 | 3 |
| RASSF6 | GNAL | 0.688117 | 3 | 0 | 3 |
| RASSF6 | COLCA2 | 0.683599 | 3 | 0 | 3 |
| RASSF6 | PAQR6 | 0.682858 | 3 | 0 | 3 |
| RASSF6 | EDRF1 | 0.678642 | 3 | 0 | 3 |
| RASSF6 | GRTP1 | 0.676403 | 3 | 0 | 3 |
| RASSF6 | MID1 | 0.674789 | 4 | 0 | 3 |
| RASSF6 | ENGASE | 0.67147 | 3 | 0 | 3 |
| RASSF6 | ATP2B3 | 0.665567 | 3 | 0 | 3 |
| RASSF6 | PLEKHH3 | 0.665405 | 3 | 0 | 3 |
| RASSF6 | PARS2 | 0.656248 | 3 | 0 | 3 |
| RASSF6 | MAP3K9 | 0.65563 | 3 | 0 | 3 |
| RASSF6 | PGBD2 | 0.646709 | 3 | 0 | 3 |
| RASSF6 | TFAP2C | 0.636117 | 3 | 0 | 3 |
| RASSF6 | SIGIRR | 0.631063 | 4 | 0 | 3 |
| RASSF6 | LRFN2 | 0.628353 | 4 | 0 | 3 |
For details and further investigation, click here
