| Full name: cytochrome c oxidase subunit 7A1 | Alias Symbol: COX7AH | ||
| Type: protein-coding gene | Cytoband: 19q13.12 | ||
| Entrez ID: 1346 | HGNC ID: HGNC:2287 | Ensembl Gene: ENSG00000161281 | OMIM ID: 123995 |
| Drug and gene relationship at DGIdb | |||
Expression of COX7A1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | COX7A1 | 1346 | 204570_at | -1.3803 | 0.1768 | |
| GSE20347 | COX7A1 | 1346 | 204570_at | -0.9118 | 0.0210 | |
| GSE23400 | COX7A1 | 1346 | 204570_at | -1.1005 | 0.0000 | |
| GSE26886 | COX7A1 | 1346 | 204570_at | 0.9256 | 0.0033 | |
| GSE29001 | COX7A1 | 1346 | 204570_at | -0.8717 | 0.0404 | |
| GSE38129 | COX7A1 | 1346 | 204570_at | -1.5224 | 0.0017 | |
| GSE45670 | COX7A1 | 1346 | 204570_at | -1.9050 | 0.0000 | |
| GSE53622 | COX7A1 | 1346 | 106777 | -1.3588 | 0.0000 | |
| GSE53624 | COX7A1 | 1346 | 106777 | -1.0438 | 0.0000 | |
| GSE63941 | COX7A1 | 1346 | 204570_at | -6.2418 | 0.0000 | |
| GSE77861 | COX7A1 | 1346 | 204570_at | 0.4270 | 0.0806 | |
| GSE97050 | COX7A1 | 1346 | A_23_P67661 | -1.5546 | 0.1012 | |
| SRP007169 | COX7A1 | 1346 | RNAseq | -1.0094 | 0.1021 | |
| SRP064894 | COX7A1 | 1346 | RNAseq | -1.3468 | 0.0010 | |
| SRP133303 | COX7A1 | 1346 | RNAseq | -0.6772 | 0.1357 | |
| SRP159526 | COX7A1 | 1346 | RNAseq | -0.8900 | 0.0385 | |
| SRP219564 | COX7A1 | 1346 | RNAseq | -1.6491 | 0.1028 | |
| TCGA | COX7A1 | 1346 | RNAseq | -0.6068 | 0.0007 |
Upregulated datasets: 0; Downregulated datasets: 7.
Survival by COX7A1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of COX7A1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | COX7A1 | 1346 | 8 | 4 | 18 | |
| GSE20123 | COX7A1 | 1346 | 8 | 3 | 19 | |
| GSE43470 | COX7A1 | 1346 | 3 | 7 | 33 | |
| GSE46452 | COX7A1 | 1346 | 48 | 1 | 10 | |
| GSE47630 | COX7A1 | 1346 | 9 | 5 | 26 | |
| GSE54993 | COX7A1 | 1346 | 17 | 3 | 50 | |
| GSE54994 | COX7A1 | 1346 | 6 | 9 | 38 | |
| GSE60625 | COX7A1 | 1346 | 9 | 0 | 2 | |
| GSE74703 | COX7A1 | 1346 | 3 | 4 | 29 | |
| GSE74704 | COX7A1 | 1346 | 7 | 1 | 12 | |
| TCGA | COX7A1 | 1346 | 22 | 10 | 64 |
Total number of gains: 140; Total number of losses: 47; Total Number of normals: 301.
Somatic mutations of COX7A1:
Generating mutation plots.
Highly correlated genes for COX7A1:
Showing top 20/1123 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| COX7A1 | UBXN10 | 0.878193 | 3 | 0 | 3 |
| COX7A1 | NEGR1 | 0.8595 | 6 | 0 | 6 |
| COX7A1 | MIR100HG | 0.858678 | 5 | 0 | 5 |
| COX7A1 | ARHGAP6 | 0.851863 | 10 | 0 | 10 |
| COX7A1 | INMT | 0.830899 | 7 | 0 | 7 |
| COX7A1 | MGARP | 0.824875 | 3 | 0 | 3 |
| COX7A1 | ZNF132 | 0.818561 | 3 | 0 | 3 |
| COX7A1 | MRVI1 | 0.81707 | 8 | 0 | 7 |
| COX7A1 | CYP21A2 | 0.816568 | 3 | 0 | 3 |
| COX7A1 | FLNC | 0.816486 | 11 | 0 | 11 |
| COX7A1 | XKR4 | 0.814109 | 5 | 0 | 5 |
| COX7A1 | CLEC3B | 0.811078 | 3 | 0 | 3 |
| COX7A1 | MYOCD | 0.807387 | 7 | 0 | 6 |
| COX7A1 | ASB5 | 0.806523 | 6 | 0 | 6 |
| COX7A1 | ZNF583 | 0.806426 | 3 | 0 | 3 |
| COX7A1 | BHMT2 | 0.802299 | 10 | 0 | 9 |
| COX7A1 | C11orf96 | 0.796922 | 5 | 0 | 5 |
| COX7A1 | MRGPRF | 0.795636 | 8 | 0 | 7 |
| COX7A1 | PDE5A | 0.791927 | 10 | 0 | 10 |
| COX7A1 | PREX2 | 0.790445 | 4 | 0 | 4 |
For details and further investigation, click here
