| Full name: MAS related GPR family member F | Alias Symbol: MGC21621|mrgF | ||
| Type: protein-coding gene | Cytoband: 11q13.3 | ||
| Entrez ID: 116535 | HGNC ID: HGNC:24828 | Ensembl Gene: ENSG00000172935 | OMIM ID: 607233 |
| Drug and gene relationship at DGIdb | |||
Expression of MRGPRF:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MRGPRF | 116535 | 227727_at | -0.5545 | 0.3964 | |
| GSE26886 | MRGPRF | 116535 | 227727_at | 1.5058 | 0.0030 | |
| GSE45670 | MRGPRF | 116535 | 227727_at | -2.4772 | 0.0000 | |
| GSE53622 | MRGPRF | 116535 | 135853 | -0.8599 | 0.0000 | |
| GSE53624 | MRGPRF | 116535 | 77764 | -0.8503 | 0.0000 | |
| GSE63941 | MRGPRF | 116535 | 227727_at | -4.8035 | 0.0000 | |
| GSE77861 | MRGPRF | 116535 | 227727_at | -0.0112 | 0.9407 | |
| GSE97050 | MRGPRF | 116535 | A_33_P3251984 | -0.7736 | 0.1863 | |
| SRP007169 | MRGPRF | 116535 | RNAseq | 1.6796 | 0.0363 | |
| SRP008496 | MRGPRF | 116535 | RNAseq | 3.7484 | 0.0001 | |
| SRP064894 | MRGPRF | 116535 | RNAseq | -0.7158 | 0.0441 | |
| SRP133303 | MRGPRF | 116535 | RNAseq | -0.4917 | 0.3066 | |
| SRP159526 | MRGPRF | 116535 | RNAseq | 0.0121 | 0.9857 | |
| SRP193095 | MRGPRF | 116535 | RNAseq | 1.1778 | 0.0032 | |
| SRP219564 | MRGPRF | 116535 | RNAseq | -0.2059 | 0.8396 | |
| TCGA | MRGPRF | 116535 | RNAseq | -0.4990 | 0.0029 |
Upregulated datasets: 4; Downregulated datasets: 2.
Survival by MRGPRF expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MRGPRF:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MRGPRF | 116535 | 13 | 2 | 15 | |
| GSE20123 | MRGPRF | 116535 | 13 | 2 | 15 | |
| GSE43470 | MRGPRF | 116535 | 13 | 3 | 27 | |
| GSE46452 | MRGPRF | 116535 | 32 | 1 | 26 | |
| GSE47630 | MRGPRF | 116535 | 19 | 1 | 20 | |
| GSE54993 | MRGPRF | 116535 | 1 | 16 | 53 | |
| GSE54994 | MRGPRF | 116535 | 25 | 3 | 25 | |
| GSE60625 | MRGPRF | 116535 | 0 | 4 | 7 | |
| GSE74703 | MRGPRF | 116535 | 10 | 2 | 24 | |
| GSE74704 | MRGPRF | 116535 | 10 | 0 | 10 | |
| TCGA | MRGPRF | 116535 | 53 | 3 | 40 |
Total number of gains: 189; Total number of losses: 37; Total Number of normals: 262.
Somatic mutations of MRGPRF:
Generating mutation plots.
Highly correlated genes for MRGPRF:
Showing top 20/1279 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MRGPRF | DIXDC1 | 0.876617 | 6 | 0 | 6 |
| MRGPRF | SYNC | 0.869081 | 4 | 0 | 4 |
| MRGPRF | NKAPL | 0.849308 | 3 | 0 | 3 |
| MRGPRF | JPH2 | 0.847883 | 3 | 0 | 3 |
| MRGPRF | SGCD | 0.846376 | 7 | 0 | 7 |
| MRGPRF | MRVI1 | 0.845008 | 7 | 0 | 7 |
| MRGPRF | NKX6-1 | 0.844531 | 4 | 0 | 4 |
| MRGPRF | PRKG1 | 0.839621 | 7 | 0 | 7 |
| MRGPRF | PEG3 | 0.8305 | 4 | 0 | 4 |
| MRGPRF | MEOX2 | 0.828076 | 5 | 0 | 5 |
| MRGPRF | MSRB3 | 0.826648 | 7 | 0 | 7 |
| MRGPRF | ZCCHC24 | 0.826535 | 8 | 0 | 8 |
| MRGPRF | NEGR1 | 0.82545 | 6 | 0 | 6 |
| MRGPRF | RASSF3 | 0.825315 | 4 | 0 | 4 |
| MRGPRF | MGARP | 0.823675 | 3 | 0 | 3 |
| MRGPRF | TRAK1 | 0.811977 | 3 | 0 | 3 |
| MRGPRF | AGTR1 | 0.811367 | 7 | 0 | 7 |
| MRGPRF | TBX5 | 0.811272 | 7 | 0 | 7 |
| MRGPRF | PDE5A | 0.805559 | 7 | 0 | 7 |
| MRGPRF | ANPEP | 0.805166 | 3 | 0 | 3 |
For details and further investigation, click here
