| Full name: cartilage associated protein | Alias Symbol: CASP|LEPREL3|P3H5 | ||
| Type: protein-coding gene | Cytoband: 3p22.3 | ||
| Entrez ID: 10491 | HGNC ID: HGNC:2379 | Ensembl Gene: ENSG00000170275 | OMIM ID: 605497 |
| Drug and gene relationship at DGIdb | |||
Expression of CRTAP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CRTAP | 10491 | 1555889_a_at | 0.0197 | 0.9769 | |
| GSE20347 | CRTAP | 10491 | 201380_at | -0.1004 | 0.5504 | |
| GSE23400 | CRTAP | 10491 | 201380_at | 0.0269 | 0.7121 | |
| GSE26886 | CRTAP | 10491 | 1555889_a_at | 0.5713 | 0.0032 | |
| GSE29001 | CRTAP | 10491 | 201380_at | -0.0911 | 0.7596 | |
| GSE38129 | CRTAP | 10491 | 201380_at | -0.3458 | 0.0381 | |
| GSE45670 | CRTAP | 10491 | 1555889_a_at | -0.5124 | 0.0021 | |
| GSE53622 | CRTAP | 10491 | 16580 | -1.2405 | 0.0000 | |
| GSE53624 | CRTAP | 10491 | 16580 | -0.8282 | 0.0000 | |
| GSE63941 | CRTAP | 10491 | 1555889_a_at | -0.9470 | 0.1002 | |
| GSE77861 | CRTAP | 10491 | 1555889_a_at | 0.2734 | 0.3592 | |
| GSE97050 | CRTAP | 10491 | A_24_P71661 | -1.3014 | 0.0887 | |
| SRP007169 | CRTAP | 10491 | RNAseq | 0.2702 | 0.4597 | |
| SRP008496 | CRTAP | 10491 | RNAseq | 0.3273 | 0.1051 | |
| SRP064894 | CRTAP | 10491 | RNAseq | 0.1178 | 0.6385 | |
| SRP133303 | CRTAP | 10491 | RNAseq | -0.4056 | 0.0482 | |
| SRP159526 | CRTAP | 10491 | RNAseq | -0.3211 | 0.3555 | |
| SRP193095 | CRTAP | 10491 | RNAseq | 0.0079 | 0.9434 | |
| SRP219564 | CRTAP | 10491 | RNAseq | -0.0686 | 0.8895 | |
| TCGA | CRTAP | 10491 | RNAseq | -0.1287 | 0.0060 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by CRTAP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CRTAP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CRTAP | 10491 | 0 | 18 | 12 | |
| GSE20123 | CRTAP | 10491 | 0 | 18 | 12 | |
| GSE43470 | CRTAP | 10491 | 1 | 19 | 23 | |
| GSE46452 | CRTAP | 10491 | 2 | 17 | 40 | |
| GSE47630 | CRTAP | 10491 | 1 | 25 | 14 | |
| GSE54993 | CRTAP | 10491 | 6 | 3 | 61 | |
| GSE54994 | CRTAP | 10491 | 1 | 32 | 20 | |
| GSE60625 | CRTAP | 10491 | 5 | 0 | 6 | |
| GSE74703 | CRTAP | 10491 | 1 | 16 | 19 | |
| GSE74704 | CRTAP | 10491 | 0 | 12 | 8 | |
| TCGA | CRTAP | 10491 | 1 | 69 | 26 |
Total number of gains: 18; Total number of losses: 229; Total Number of normals: 241.
Somatic mutations of CRTAP:
Generating mutation plots.
Highly correlated genes for CRTAP:
Showing top 20/917 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CRTAP | SORCS1 | 0.771574 | 3 | 0 | 3 |
| CRTAP | CLEC3B | 0.758692 | 3 | 0 | 3 |
| CRTAP | MBNL1-AS1 | 0.75297 | 3 | 0 | 3 |
| CRTAP | XKR4 | 0.747511 | 4 | 0 | 4 |
| CRTAP | TCEAL6 | 0.746008 | 3 | 0 | 3 |
| CRTAP | CYP21A2 | 0.743532 | 3 | 0 | 3 |
| CRTAP | SGTB | 0.737855 | 5 | 0 | 4 |
| CRTAP | PDK2 | 0.734743 | 3 | 0 | 3 |
| CRTAP | GPRASP2 | 0.726068 | 3 | 0 | 3 |
| CRTAP | TCEAL5 | 0.719153 | 3 | 0 | 3 |
| CRTAP | OGN | 0.717736 | 6 | 0 | 6 |
| CRTAP | BCORL1 | 0.717159 | 3 | 0 | 3 |
| CRTAP | ITGA9 | 0.712564 | 4 | 0 | 4 |
| CRTAP | MAPRE3 | 0.710934 | 3 | 0 | 3 |
| CRTAP | PTPN9 | 0.710686 | 4 | 0 | 4 |
| CRTAP | PDZRN4 | 0.710526 | 6 | 0 | 6 |
| CRTAP | RERGL | 0.709058 | 5 | 0 | 5 |
| CRTAP | KLHL15 | 0.705075 | 5 | 0 | 5 |
| CRTAP | UBE2Q2 | 0.704012 | 3 | 0 | 3 |
| CRTAP | LYVE1 | 0.701984 | 6 | 0 | 5 |
For details and further investigation, click here
