| Full name: ubiquitin conjugating enzyme E2 Q2 | Alias Symbol: DKFZp762C143 | ||
| Type: protein-coding gene | Cytoband: 15q24.2 | ||
| Entrez ID: 92912 | HGNC ID: HGNC:19248 | Ensembl Gene: ENSG00000140367 | OMIM ID: 612501 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of UBE2Q2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | UBE2Q2 | 92912 | 224747_at | -0.1749 | 0.8091 | |
| GSE26886 | UBE2Q2 | 92912 | 224747_at | -0.1948 | 0.5043 | |
| GSE45670 | UBE2Q2 | 92912 | 224747_at | 0.2470 | 0.3216 | |
| GSE53622 | UBE2Q2 | 92912 | 37101 | 0.2464 | 0.0370 | |
| GSE53624 | UBE2Q2 | 92912 | 37101 | 0.1917 | 0.0026 | |
| GSE63941 | UBE2Q2 | 92912 | 224747_at | -1.2818 | 0.0125 | |
| GSE77861 | UBE2Q2 | 92912 | 224747_at | 0.0469 | 0.9313 | |
| GSE97050 | UBE2Q2 | 92912 | A_33_P3333826 | -0.3260 | 0.2038 | |
| SRP007169 | UBE2Q2 | 92912 | RNAseq | 0.3601 | 0.3976 | |
| SRP008496 | UBE2Q2 | 92912 | RNAseq | 0.4289 | 0.0824 | |
| SRP064894 | UBE2Q2 | 92912 | RNAseq | 0.4131 | 0.0075 | |
| SRP133303 | UBE2Q2 | 92912 | RNAseq | 0.6892 | 0.0008 | |
| SRP159526 | UBE2Q2 | 92912 | RNAseq | -0.0174 | 0.9505 | |
| SRP193095 | UBE2Q2 | 92912 | RNAseq | 0.3881 | 0.0037 | |
| SRP219564 | UBE2Q2 | 92912 | RNAseq | -0.3703 | 0.2894 | |
| TCGA | UBE2Q2 | 92912 | RNAseq | 0.0029 | 0.9621 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by UBE2Q2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of UBE2Q2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UBE2Q2 | 92912 | 8 | 1 | 21 | |
| GSE20123 | UBE2Q2 | 92912 | 8 | 1 | 21 | |
| GSE43470 | UBE2Q2 | 92912 | 4 | 6 | 33 | |
| GSE46452 | UBE2Q2 | 92912 | 3 | 7 | 49 | |
| GSE47630 | UBE2Q2 | 92912 | 8 | 10 | 22 | |
| GSE54993 | UBE2Q2 | 92912 | 5 | 6 | 59 | |
| GSE54994 | UBE2Q2 | 92912 | 5 | 6 | 42 | |
| GSE60625 | UBE2Q2 | 92912 | 4 | 0 | 7 | |
| GSE74703 | UBE2Q2 | 92912 | 4 | 3 | 29 | |
| GSE74704 | UBE2Q2 | 92912 | 4 | 1 | 15 | |
| TCGA | UBE2Q2 | 92912 | 14 | 15 | 67 |
Total number of gains: 67; Total number of losses: 56; Total Number of normals: 365.
Somatic mutations of UBE2Q2:
Generating mutation plots.
Highly correlated genes for UBE2Q2:
Showing top 20/326 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UBE2Q2 | ANG | 0.797424 | 3 | 0 | 3 |
| UBE2Q2 | PLEKHM3 | 0.767053 | 3 | 0 | 3 |
| UBE2Q2 | MCAM | 0.766547 | 3 | 0 | 3 |
| UBE2Q2 | DOCK11 | 0.759891 | 3 | 0 | 3 |
| UBE2Q2 | SNX15 | 0.758007 | 3 | 0 | 3 |
| UBE2Q2 | EDNRB | 0.757308 | 3 | 0 | 3 |
| UBE2Q2 | CEP112 | 0.757066 | 3 | 0 | 3 |
| UBE2Q2 | TCF21 | 0.756595 | 3 | 0 | 3 |
| UBE2Q2 | KIF5B | 0.753641 | 3 | 0 | 3 |
| UBE2Q2 | IREB2 | 0.743074 | 3 | 0 | 3 |
| UBE2Q2 | TBC1D19 | 0.73386 | 4 | 0 | 3 |
| UBE2Q2 | SACM1L | 0.722723 | 3 | 0 | 3 |
| UBE2Q2 | PEAK1 | 0.717399 | 3 | 0 | 3 |
| UBE2Q2 | LSM10 | 0.716518 | 3 | 0 | 3 |
| UBE2Q2 | NAPG | 0.715428 | 3 | 0 | 3 |
| UBE2Q2 | BBS9 | 0.713643 | 4 | 0 | 3 |
| UBE2Q2 | MAP4 | 0.713137 | 4 | 0 | 4 |
| UBE2Q2 | TXNDC15 | 0.711571 | 3 | 0 | 3 |
| UBE2Q2 | GLYR1 | 0.711003 | 3 | 0 | 3 |
| UBE2Q2 | MKNK1 | 0.709795 | 3 | 0 | 3 |
For details and further investigation, click here
