CSMD1

 

Full name: CUB and Sushi multiple domains 1 Alias Symbol: KIAA1890|PPP1R24
Type: protein-coding gene Cytoband: 8p23.2
Entrez ID: 64478 HGNC ID: HGNC:14026 Ensembl Gene: ENSG00000183117 OMIM ID: 608397
Drug and gene relationship at DGIdb

 

Expression of CSMD1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 CSMD1 64478 1553405_a_at -0.3380 0.2342
GSE26886 CSMD1 64478 241960_at 0.2047 0.1476
GSE45670 CSMD1 64478 1562330_s_at 0.0615 0.5134
GSE53622 CSMD1 64478 3681 -0.4078 0.0262
GSE53624 CSMD1 64478 3681 -0.7910 0.0000
GSE63941 CSMD1 64478 1562330_s_at 0.0338 0.8794
GSE77861 CSMD1 64478 1553405_a_at -0.3075 0.0189
SRP133303 CSMD1 64478 RNAseq -1.1264 0.0347
SRP159526 CSMD1 64478 RNAseq 3.2278 0.0004
TCGA CSMD1 64478 RNAseq 0.3943 0.5625

Upregulated datasets: 1; Downregulated datasets: 1.  


 

Survival by CSMD1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of CSMD1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 CSMD1 64478 4 16 10
GSE20123 CSMD1 64478 5 15 10
GSE43470 CSMD1 64478 6 11 26
GSE46452 CSMD1 64478 12 14 33
GSE47630 CSMD1 64478 10 11 19
GSE54993 CSMD1 64478 4 14 52
GSE54994 CSMD1 64478 9 20 24
GSE60625 CSMD1 64478 3 0 8
GSE74703 CSMD1 64478 6 9 21
GSE74704 CSMD1 64478 4 10 6
TCGA CSMD1 64478 15 57 24

Total number of gains: 78; Total number of losses: 177; Total Number of normals: 233.  


 

Somatic mutations of CSMD1:

 

Generating mutation plots.

 

Highly correlated genes for CSMD1:

 

Showing top 20/28 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
CSMD1MCHR20.678597303
CSMD1NAV2-AS50.668301303
CSMD1FUT60.647236303
CSMD1SYAP10.637086303
CSMD1USP540.63612303
CSMD1C20orf1730.616532303
CSMD1PADI40.615443303
CSMD1HTR3C0.605946303
CSMD1RER10.597258303
CSMD1C3orf350.594162303
CSMD1LINC003270.588142303
CSMD1RTP50.584801303
CSMD1SLC26A70.576706403
CSMD1CHRNA20.575548303
CSMD1BARX20.569013303
CSMD1OR2J30.565129303
CSMD1RLBP10.549219403
CSMD1LELP10.546811403
CSMD1INSRR0.543762303
CSMD1SPATA90.541709303

For details and further investigation, click here