| Full name: fucosyltransferase 6 | Alias Symbol: FT1A|FCT3A|FucT-VI|FLJ40754 | ||
| Type: protein-coding gene | Cytoband: 19p13.3 | ||
| Entrez ID: 2528 | HGNC ID: HGNC:4017 | Ensembl Gene: ENSG00000156413 | OMIM ID: 136836 |
| Drug and gene relationship at DGIdb | |||
Expression of FUT6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FUT6 | 2528 | 211465_x_at | -1.7188 | 0.1511 | |
| GSE20347 | FUT6 | 2528 | 211465_x_at | -1.8924 | 0.0000 | |
| GSE23400 | FUT6 | 2528 | 211465_x_at | -1.6923 | 0.0000 | |
| GSE26886 | FUT6 | 2528 | 211465_x_at | -2.7282 | 0.0000 | |
| GSE29001 | FUT6 | 2528 | 211465_x_at | -2.3248 | 0.0000 | |
| GSE38129 | FUT6 | 2528 | 211465_x_at | -1.6748 | 0.0001 | |
| GSE45670 | FUT6 | 2528 | 211465_x_at | -0.9021 | 0.0439 | |
| GSE53622 | FUT6 | 2528 | 56815 | 1.1401 | 0.0000 | |
| GSE53624 | FUT6 | 2528 | 56815 | 0.7006 | 0.0000 | |
| GSE63941 | FUT6 | 2528 | 211465_x_at | 0.6876 | 0.0670 | |
| GSE77861 | FUT6 | 2528 | 211465_x_at | -1.2567 | 0.0007 | |
| GSE97050 | FUT6 | 2528 | A_33_P3210288 | 0.3906 | 0.1626 | |
| SRP007169 | FUT6 | 2528 | RNAseq | -5.5157 | 0.0000 | |
| SRP008496 | FUT6 | 2528 | RNAseq | -5.6879 | 0.0000 | |
| SRP064894 | FUT6 | 2528 | RNAseq | -4.0859 | 0.0000 | |
| SRP133303 | FUT6 | 2528 | RNAseq | -3.0747 | 0.0000 | |
| SRP159526 | FUT6 | 2528 | RNAseq | -5.6310 | 0.0000 | |
| SRP193095 | FUT6 | 2528 | RNAseq | -3.2196 | 0.0000 | |
| SRP219564 | FUT6 | 2528 | RNAseq | -4.3839 | 0.0001 | |
| TCGA | FUT6 | 2528 | RNAseq | -0.0920 | 0.8543 |
Upregulated datasets: 1; Downregulated datasets: 13.
Survival by FUT6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FUT6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FUT6 | 2528 | 5 | 3 | 22 | |
| GSE20123 | FUT6 | 2528 | 4 | 2 | 24 | |
| GSE43470 | FUT6 | 2528 | 2 | 6 | 35 | |
| GSE46452 | FUT6 | 2528 | 47 | 1 | 11 | |
| GSE47630 | FUT6 | 2528 | 5 | 7 | 28 | |
| GSE54993 | FUT6 | 2528 | 16 | 3 | 51 | |
| GSE54994 | FUT6 | 2528 | 6 | 16 | 31 | |
| GSE60625 | FUT6 | 2528 | 9 | 0 | 2 | |
| GSE74703 | FUT6 | 2528 | 2 | 4 | 30 | |
| GSE74704 | FUT6 | 2528 | 1 | 2 | 17 | |
| TCGA | FUT6 | 2528 | 10 | 18 | 68 |
Total number of gains: 107; Total number of losses: 62; Total Number of normals: 319.
Somatic mutations of FUT6:
Generating mutation plots.
Highly correlated genes for FUT6:
Showing top 20/381 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FUT6 | CLIC3 | 0.895827 | 8 | 0 | 8 |
| FUT6 | PADI1 | 0.875598 | 9 | 0 | 9 |
| FUT6 | PRSS2 | 0.861599 | 8 | 0 | 8 |
| FUT6 | GBP6 | 0.848894 | 5 | 0 | 5 |
| FUT6 | PSCA | 0.840764 | 9 | 0 | 9 |
| FUT6 | SPNS2 | 0.824001 | 5 | 0 | 4 |
| FUT6 | GLTP | 0.810713 | 8 | 0 | 8 |
| FUT6 | SFTA2 | 0.809067 | 5 | 0 | 5 |
| FUT6 | SULT2B1 | 0.802512 | 9 | 0 | 9 |
| FUT6 | ACAA1 | 0.789683 | 8 | 0 | 7 |
| FUT6 | EPB41L4A | 0.781779 | 9 | 0 | 9 |
| FUT6 | B3GNT8 | 0.779687 | 4 | 0 | 4 |
| FUT6 | RIPK4 | 0.772625 | 9 | 0 | 8 |
| FUT6 | BCYRN1 | 0.771123 | 3 | 0 | 3 |
| FUT6 | GCHFR | 0.770088 | 9 | 0 | 8 |
| FUT6 | SNORA68 | 0.766525 | 5 | 0 | 4 |
| FUT6 | SH3PXD2A-AS1 | 0.764463 | 4 | 0 | 4 |
| FUT6 | CSTA | 0.757127 | 9 | 0 | 8 |
| FUT6 | IL22RA1 | 0.753144 | 8 | 0 | 8 |
| FUT6 | PRSS8 | 0.746839 | 9 | 0 | 9 |
For details and further investigation, click here
