| Full name: melanin concentrating hormone receptor 2 | Alias Symbol: SLT|MCH2|MCH2R | ||
| Type: protein-coding gene | Cytoband: 6q16.2 | ||
| Entrez ID: 84539 | HGNC ID: HGNC:20867 | Ensembl Gene: ENSG00000152034 | OMIM ID: 606111 |
| Drug and gene relationship at DGIdb | |||
Expression of MCHR2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MCHR2 | 84539 | 224408_at | -0.0990 | 0.7282 | |
| GSE26886 | MCHR2 | 84539 | 224408_at | -0.2269 | 0.0310 | |
| GSE45670 | MCHR2 | 84539 | 224408_at | 0.0532 | 0.5527 | |
| GSE53622 | MCHR2 | 84539 | 130589 | 0.1016 | 0.4557 | |
| GSE53624 | MCHR2 | 84539 | 130589 | 0.8713 | 0.0000 | |
| GSE63941 | MCHR2 | 84539 | 224408_at | -0.0023 | 0.9885 | |
| GSE77861 | MCHR2 | 84539 | 224408_at | -0.1437 | 0.0963 | |
| SRP133303 | MCHR2 | 84539 | RNAseq | 0.3459 | 0.1664 | |
| TCGA | MCHR2 | 84539 | RNAseq | 2.8288 | 0.0318 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by MCHR2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MCHR2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MCHR2 | 84539 | 1 | 3 | 26 | |
| GSE20123 | MCHR2 | 84539 | 1 | 2 | 27 | |
| GSE43470 | MCHR2 | 84539 | 3 | 0 | 40 | |
| GSE46452 | MCHR2 | 84539 | 2 | 11 | 46 | |
| GSE47630 | MCHR2 | 84539 | 8 | 6 | 26 | |
| GSE54993 | MCHR2 | 84539 | 3 | 2 | 65 | |
| GSE54994 | MCHR2 | 84539 | 8 | 8 | 37 | |
| GSE60625 | MCHR2 | 84539 | 0 | 1 | 10 | |
| GSE74703 | MCHR2 | 84539 | 2 | 0 | 34 | |
| GSE74704 | MCHR2 | 84539 | 0 | 0 | 20 | |
| TCGA | MCHR2 | 84539 | 7 | 23 | 66 |
Total number of gains: 35; Total number of losses: 56; Total Number of normals: 397.
Somatic mutations of MCHR2:
Generating mutation plots.
Highly correlated genes for MCHR2:
Showing top 20/84 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MCHR2 | KCNK17 | 0.708373 | 3 | 0 | 3 |
| MCHR2 | ENHO | 0.692249 | 3 | 0 | 3 |
| MCHR2 | KCNJ5 | 0.683795 | 3 | 0 | 3 |
| MCHR2 | TTTY11 | 0.678832 | 3 | 0 | 3 |
| MCHR2 | CSMD1 | 0.678597 | 3 | 0 | 3 |
| MCHR2 | NCAN | 0.663724 | 3 | 0 | 3 |
| MCHR2 | KIF25 | 0.655912 | 3 | 0 | 3 |
| MCHR2 | MEP1B | 0.646301 | 4 | 0 | 3 |
| MCHR2 | UNC5C | 0.643878 | 3 | 0 | 3 |
| MCHR2 | NLRP8 | 0.636989 | 4 | 0 | 3 |
| MCHR2 | PNPLA4 | 0.634787 | 3 | 0 | 3 |
| MCHR2 | DCAF12L1 | 0.6342 | 3 | 0 | 3 |
| MCHR2 | OR1J2 | 0.632853 | 4 | 0 | 4 |
| MCHR2 | KCNJ6 | 0.63063 | 3 | 0 | 3 |
| MCHR2 | SIGLEC6 | 0.629199 | 4 | 0 | 3 |
| MCHR2 | CA1 | 0.62382 | 3 | 0 | 3 |
| MCHR2 | PHF7 | 0.612058 | 4 | 0 | 3 |
| MCHR2 | A1CF | 0.609718 | 4 | 0 | 3 |
| MCHR2 | KCNIP1 | 0.607098 | 3 | 0 | 3 |
| MCHR2 | C1orf61 | 0.606395 | 4 | 0 | 3 |
For details and further investigation, click here
