| Full name: retention in endoplasmic reticulum sorting receptor 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1p36.32 | ||
| Entrez ID: 11079 | HGNC ID: HGNC:30309 | Ensembl Gene: ENSG00000157916 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of RER1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RER1 | 11079 | 202296_s_at | -0.1851 | 0.7703 | |
| GSE20347 | RER1 | 11079 | 202296_s_at | -1.1310 | 0.0000 | |
| GSE23400 | RER1 | 11079 | 202296_s_at | -0.5599 | 0.0000 | |
| GSE26886 | RER1 | 11079 | 202297_s_at | -0.1378 | 0.5433 | |
| GSE29001 | RER1 | 11079 | 202297_s_at | -0.4328 | 0.0144 | |
| GSE38129 | RER1 | 11079 | 202296_s_at | -0.5745 | 0.0059 | |
| GSE45670 | RER1 | 11079 | 202296_s_at | -0.3348 | 0.0986 | |
| GSE53622 | RER1 | 11079 | 39146 | -0.6961 | 0.0000 | |
| GSE53624 | RER1 | 11079 | 39146 | -1.0403 | 0.0000 | |
| GSE63941 | RER1 | 11079 | 202296_s_at | -0.2344 | 0.5909 | |
| GSE77861 | RER1 | 11079 | 202296_s_at | -0.9848 | 0.0013 | |
| GSE97050 | RER1 | 11079 | A_33_P3353712 | -0.0255 | 0.9572 | |
| SRP007169 | RER1 | 11079 | RNAseq | -1.9405 | 0.0000 | |
| SRP008496 | RER1 | 11079 | RNAseq | -1.7666 | 0.0000 | |
| SRP064894 | RER1 | 11079 | RNAseq | -0.1739 | 0.4286 | |
| SRP133303 | RER1 | 11079 | RNAseq | -0.2401 | 0.1442 | |
| SRP159526 | RER1 | 11079 | RNAseq | -0.6156 | 0.0028 | |
| SRP193095 | RER1 | 11079 | RNAseq | -0.7818 | 0.0000 | |
| SRP219564 | RER1 | 11079 | RNAseq | -0.4248 | 0.1451 | |
| TCGA | RER1 | 11079 | RNAseq | -0.0919 | 0.0395 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by RER1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RER1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RER1 | 11079 | 4 | 6 | 20 | |
| GSE20123 | RER1 | 11079 | 4 | 5 | 21 | |
| GSE43470 | RER1 | 11079 | 3 | 5 | 35 | |
| GSE46452 | RER1 | 11079 | 7 | 1 | 51 | |
| GSE47630 | RER1 | 11079 | 8 | 4 | 28 | |
| GSE54993 | RER1 | 11079 | 3 | 2 | 65 | |
| GSE54994 | RER1 | 11079 | 15 | 2 | 36 | |
| GSE60625 | RER1 | 11079 | 0 | 0 | 11 | |
| GSE74703 | RER1 | 11079 | 3 | 3 | 30 | |
| GSE74704 | RER1 | 11079 | 4 | 0 | 16 | |
| TCGA | RER1 | 11079 | 14 | 20 | 62 |
Total number of gains: 65; Total number of losses: 48; Total Number of normals: 375.
Somatic mutations of RER1:
Generating mutation plots.
Highly correlated genes for RER1:
Showing top 20/1373 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RER1 | SMAGP | 0.794959 | 9 | 0 | 9 |
| RER1 | GALE | 0.787972 | 10 | 0 | 10 |
| RER1 | ORMDL2 | 0.778277 | 8 | 0 | 8 |
| RER1 | TXNDC17 | 0.776088 | 3 | 0 | 3 |
| RER1 | SMC5 | 0.767223 | 3 | 0 | 3 |
| RER1 | ASCC2 | 0.765628 | 10 | 0 | 10 |
| RER1 | EPGN | 0.765167 | 3 | 0 | 3 |
| RER1 | BLNK | 0.757 | 10 | 0 | 10 |
| RER1 | PHACTR4 | 0.750231 | 10 | 0 | 10 |
| RER1 | ZNF416 | 0.748832 | 4 | 0 | 4 |
| RER1 | TECR | 0.748296 | 8 | 0 | 8 |
| RER1 | MFSD5 | 0.746224 | 11 | 0 | 9 |
| RER1 | GMDS | 0.742615 | 10 | 0 | 10 |
| RER1 | DDI2 | 0.740812 | 3 | 0 | 3 |
| RER1 | SH3GL1 | 0.739094 | 10 | 0 | 9 |
| RER1 | C15orf48 | 0.736474 | 5 | 0 | 5 |
| RER1 | TOM1 | 0.736365 | 10 | 0 | 9 |
| RER1 | NAGK | 0.735755 | 11 | 0 | 11 |
| RER1 | CYP2J2 | 0.73522 | 9 | 0 | 9 |
| RER1 | VSIG2 | 0.732937 | 5 | 0 | 5 |
For details and further investigation, click here
