| Full name: ubiquitin specific peptidase 54 | Alias Symbol: FLJ37318|bA137L10.3|bA137L10.4 | ||
| Type: protein-coding gene | Cytoband: 10q22.2 | ||
| Entrez ID: 159195 | HGNC ID: HGNC:23513 | Ensembl Gene: ENSG00000166348 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of USP54:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | USP54 | 159195 | 227334_at | -1.1560 | 0.0764 | |
| GSE26886 | USP54 | 159195 | 227334_at | -1.4396 | 0.0000 | |
| GSE45670 | USP54 | 159195 | 227334_at | -0.4984 | 0.0384 | |
| GSE53622 | USP54 | 159195 | 13778 | -1.0983 | 0.0000 | |
| GSE53624 | USP54 | 159195 | 13778 | -1.2435 | 0.0000 | |
| GSE63941 | USP54 | 159195 | 227334_at | 1.3996 | 0.0066 | |
| GSE77861 | USP54 | 159195 | 227334_at | -0.8066 | 0.0076 | |
| GSE97050 | USP54 | 159195 | A_23_P355536 | -0.2594 | 0.3443 | |
| SRP007169 | USP54 | 159195 | RNAseq | -1.0621 | 0.0206 | |
| SRP008496 | USP54 | 159195 | RNAseq | -1.3062 | 0.0000 | |
| SRP064894 | USP54 | 159195 | RNAseq | -1.2963 | 0.0000 | |
| SRP133303 | USP54 | 159195 | RNAseq | -0.7926 | 0.0004 | |
| SRP159526 | USP54 | 159195 | RNAseq | -1.3167 | 0.0000 | |
| SRP193095 | USP54 | 159195 | RNAseq | -1.2628 | 0.0000 | |
| SRP219564 | USP54 | 159195 | RNAseq | -0.6018 | 0.1854 | |
| TCGA | USP54 | 159195 | RNAseq | -0.4702 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 8.
Survival by USP54 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of USP54:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | USP54 | 159195 | 3 | 4 | 23 | |
| GSE20123 | USP54 | 159195 | 3 | 3 | 24 | |
| GSE43470 | USP54 | 159195 | 2 | 8 | 33 | |
| GSE46452 | USP54 | 159195 | 0 | 11 | 48 | |
| GSE47630 | USP54 | 159195 | 2 | 14 | 24 | |
| GSE54993 | USP54 | 159195 | 7 | 0 | 63 | |
| GSE54994 | USP54 | 159195 | 2 | 10 | 41 | |
| GSE60625 | USP54 | 159195 | 0 | 0 | 11 | |
| GSE74703 | USP54 | 159195 | 2 | 5 | 29 | |
| GSE74704 | USP54 | 159195 | 1 | 1 | 18 | |
| TCGA | USP54 | 159195 | 11 | 23 | 62 |
Total number of gains: 33; Total number of losses: 79; Total Number of normals: 376.
Somatic mutations of USP54:
Generating mutation plots.
Highly correlated genes for USP54:
Showing top 20/1263 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| USP54 | SORT1 | 0.844491 | 7 | 0 | 7 |
| USP54 | SNORA68 | 0.816215 | 4 | 0 | 4 |
| USP54 | GPD1L | 0.815061 | 7 | 0 | 7 |
| USP54 | CAB39L | 0.814175 | 7 | 0 | 7 |
| USP54 | FAM214A | 0.812113 | 6 | 0 | 6 |
| USP54 | SH3BGRL2 | 0.804176 | 7 | 0 | 7 |
| USP54 | IKZF2 | 0.80087 | 7 | 0 | 7 |
| USP54 | NACA2 | 0.800726 | 3 | 0 | 3 |
| USP54 | KRT4 | 0.799454 | 6 | 0 | 6 |
| USP54 | ATP13A4 | 0.796182 | 6 | 0 | 6 |
| USP54 | SLC12A6 | 0.794474 | 4 | 0 | 4 |
| USP54 | ACOX1 | 0.791474 | 7 | 0 | 7 |
| USP54 | PLEKHA7 | 0.790538 | 8 | 0 | 8 |
| USP54 | SCNN1B | 0.789992 | 6 | 0 | 6 |
| USP54 | TPCN1 | 0.785692 | 7 | 0 | 7 |
| USP54 | ERBB3 | 0.785334 | 7 | 0 | 7 |
| USP54 | CHP1 | 0.785184 | 6 | 0 | 6 |
| USP54 | RAB27A | 0.784926 | 3 | 0 | 3 |
| USP54 | FAM3B | 0.783179 | 7 | 0 | 6 |
| USP54 | SHROOM3 | 0.778665 | 7 | 0 | 7 |
For details and further investigation, click here
