| Full name: chromosome 3 open reading frame 35 | Alias Symbol: APRG1 | ||
| Type: protein-coding gene | Cytoband: 3p22.2 | ||
| Entrez ID: 339883 | HGNC ID: HGNC:24082 | Ensembl Gene: ENSG00000198590 | OMIM ID: 611429 |
| Drug and gene relationship at DGIdb | |||
Expression of C3orf35:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C3orf35 | 339883 | 237368_at | -0.1596 | 0.5629 | |
| GSE26886 | C3orf35 | 339883 | 237368_at | -0.0310 | 0.8168 | |
| GSE45670 | C3orf35 | 339883 | 237368_at | 0.0076 | 0.9387 | |
| GSE63941 | C3orf35 | 339883 | 237368_at | -0.0883 | 0.5817 | |
| GSE77861 | C3orf35 | 339883 | 237368_at | -0.1054 | 0.2319 | |
| GSE97050 | C3orf35 | 339883 | A_23_P341503 | -0.1887 | 0.4867 | |
| SRP133303 | C3orf35 | 339883 | RNAseq | -0.3411 | 0.0874 | |
| SRP159526 | C3orf35 | 339883 | RNAseq | 0.1636 | 0.8017 | |
| SRP193095 | C3orf35 | 339883 | RNAseq | 0.0152 | 0.9418 | |
| SRP219564 | C3orf35 | 339883 | RNAseq | 0.0895 | 0.8820 | |
| TCGA | C3orf35 | 339883 | RNAseq | -1.0522 | 0.0007 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by C3orf35 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of C3orf35:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C3orf35 | 339883 | 0 | 18 | 12 | |
| GSE20123 | C3orf35 | 339883 | 0 | 18 | 12 | |
| GSE43470 | C3orf35 | 339883 | 0 | 20 | 23 | |
| GSE46452 | C3orf35 | 339883 | 2 | 17 | 40 | |
| GSE47630 | C3orf35 | 339883 | 1 | 25 | 14 | |
| GSE54993 | C3orf35 | 339883 | 6 | 3 | 61 | |
| GSE54994 | C3orf35 | 339883 | 1 | 32 | 20 | |
| GSE60625 | C3orf35 | 339883 | 5 | 0 | 6 | |
| GSE74703 | C3orf35 | 339883 | 0 | 16 | 20 | |
| GSE74704 | C3orf35 | 339883 | 0 | 12 | 8 | |
| TCGA | C3orf35 | 339883 | 0 | 71 | 25 |
Total number of gains: 15; Total number of losses: 232; Total Number of normals: 241.
Somatic mutations of C3orf35:
Generating mutation plots.
Highly correlated genes for C3orf35:
Showing top 20/44 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C3orf35 | GALK1 | 0.78597 | 3 | 0 | 3 |
| C3orf35 | ZDHHC15 | 0.754889 | 3 | 0 | 3 |
| C3orf35 | CCR6 | 0.749133 | 3 | 0 | 3 |
| C3orf35 | GPR182 | 0.726856 | 3 | 0 | 3 |
| C3orf35 | OR4D2 | 0.723783 | 3 | 0 | 3 |
| C3orf35 | IQCD | 0.722087 | 3 | 0 | 3 |
| C3orf35 | ATP6V0A4 | 0.71626 | 3 | 0 | 3 |
| C3orf35 | FHAD1 | 0.711135 | 3 | 0 | 3 |
| C3orf35 | RAX2 | 0.707211 | 3 | 0 | 3 |
| C3orf35 | BCL2L15 | 0.704436 | 3 | 0 | 3 |
| C3orf35 | UROC1 | 0.700105 | 3 | 0 | 3 |
| C3orf35 | DPEP3 | 0.698425 | 3 | 0 | 3 |
| C3orf35 | KLKB1 | 0.694749 | 3 | 0 | 3 |
| C3orf35 | TTLL9 | 0.689274 | 3 | 0 | 3 |
| C3orf35 | DKK4 | 0.678668 | 3 | 0 | 3 |
| C3orf35 | CDRT1 | 0.673753 | 3 | 0 | 3 |
| C3orf35 | AP4B1 | 0.656677 | 3 | 0 | 3 |
| C3orf35 | CEACAM1 | 0.640282 | 3 | 0 | 3 |
| C3orf35 | CHRNA2 | 0.640136 | 3 | 0 | 3 |
| C3orf35 | KRBOX1 | 0.632965 | 3 | 0 | 3 |
For details and further investigation, click here
