| Full name: centrosome and spindle pole associated protein 1 | Alias Symbol: FLJ22490|CSPP|JBTS21 | ||
| Type: protein-coding gene | Cytoband: 8q13.1-q13.2 | ||
| Entrez ID: 79848 | HGNC ID: HGNC:26193 | Ensembl Gene: ENSG00000104218 | OMIM ID: 611654 |
| Drug and gene relationship at DGIdb | |||
Expression of CSPP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CSPP1 | 79848 | 227105_at | 0.6539 | 0.3622 | |
| GSE20347 | CSPP1 | 79848 | 220072_at | 0.4298 | 0.0082 | |
| GSE23400 | CSPP1 | 79848 | 220072_at | 0.2317 | 0.0111 | |
| GSE26886 | CSPP1 | 79848 | 227105_at | 0.4428 | 0.1896 | |
| GSE29001 | CSPP1 | 79848 | 220072_at | 0.4177 | 0.1154 | |
| GSE38129 | CSPP1 | 79848 | 220072_at | 0.4525 | 0.0279 | |
| GSE45670 | CSPP1 | 79848 | 227105_at | 0.3085 | 0.0709 | |
| GSE53622 | CSPP1 | 79848 | 52721 | 0.3539 | 0.0000 | |
| GSE53624 | CSPP1 | 79848 | 52721 | 0.4835 | 0.0000 | |
| GSE63941 | CSPP1 | 79848 | 227105_at | -1.8108 | 0.0045 | |
| GSE77861 | CSPP1 | 79848 | 220072_at | 0.3225 | 0.1376 | |
| GSE97050 | CSPP1 | 79848 | A_23_P71537 | -0.0480 | 0.8799 | |
| SRP007169 | CSPP1 | 79848 | RNAseq | 0.3566 | 0.4231 | |
| SRP008496 | CSPP1 | 79848 | RNAseq | 0.8185 | 0.0059 | |
| SRP064894 | CSPP1 | 79848 | RNAseq | 0.7573 | 0.0002 | |
| SRP133303 | CSPP1 | 79848 | RNAseq | 0.2299 | 0.0902 | |
| SRP159526 | CSPP1 | 79848 | RNAseq | 0.3476 | 0.0775 | |
| SRP193095 | CSPP1 | 79848 | RNAseq | 0.3944 | 0.0000 | |
| SRP219564 | CSPP1 | 79848 | RNAseq | 0.5490 | 0.1601 | |
| TCGA | CSPP1 | 79848 | RNAseq | -0.0180 | 0.7845 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by CSPP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CSPP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CSPP1 | 79848 | 15 | 1 | 14 | |
| GSE20123 | CSPP1 | 79848 | 16 | 1 | 13 | |
| GSE43470 | CSPP1 | 79848 | 15 | 3 | 25 | |
| GSE46452 | CSPP1 | 79848 | 20 | 2 | 37 | |
| GSE47630 | CSPP1 | 79848 | 23 | 1 | 16 | |
| GSE54993 | CSPP1 | 79848 | 1 | 18 | 51 | |
| GSE54994 | CSPP1 | 79848 | 30 | 0 | 23 | |
| GSE60625 | CSPP1 | 79848 | 0 | 4 | 7 | |
| GSE74703 | CSPP1 | 79848 | 13 | 2 | 21 | |
| GSE74704 | CSPP1 | 79848 | 11 | 0 | 9 | |
| TCGA | CSPP1 | 79848 | 49 | 4 | 43 |
Total number of gains: 193; Total number of losses: 36; Total Number of normals: 259.
Somatic mutations of CSPP1:
Generating mutation plots.
Highly correlated genes for CSPP1:
Showing top 20/524 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CSPP1 | DCUN1D2 | 0.817133 | 3 | 0 | 3 |
| CSPP1 | ZNF664 | 0.79528 | 3 | 0 | 3 |
| CSPP1 | ACAD11 | 0.777747 | 3 | 0 | 3 |
| CSPP1 | TOMM40L | 0.765207 | 3 | 0 | 3 |
| CSPP1 | SDAD1 | 0.758749 | 3 | 0 | 3 |
| CSPP1 | ZNF518B | 0.744072 | 3 | 0 | 3 |
| CSPP1 | GRWD1 | 0.743845 | 4 | 0 | 3 |
| CSPP1 | ALKBH6 | 0.733494 | 3 | 0 | 3 |
| CSPP1 | ELAC2 | 0.732773 | 4 | 0 | 4 |
| CSPP1 | TGFBRAP1 | 0.731065 | 3 | 0 | 3 |
| CSPP1 | KIAA1257 | 0.730809 | 3 | 0 | 3 |
| CSPP1 | ZBED6 | 0.730606 | 4 | 0 | 4 |
| CSPP1 | EEF1D | 0.725044 | 4 | 0 | 4 |
| CSPP1 | SPIRE2 | 0.724014 | 4 | 0 | 3 |
| CSPP1 | TYW5 | 0.721761 | 4 | 0 | 3 |
| CSPP1 | RICTOR | 0.719396 | 4 | 0 | 3 |
| CSPP1 | RBM12B | 0.716544 | 5 | 0 | 5 |
| CSPP1 | FAM133B | 0.713042 | 3 | 0 | 3 |
| CSPP1 | ABL2 | 0.709691 | 3 | 0 | 3 |
| CSPP1 | TMEM181 | 0.708815 | 4 | 0 | 3 |
For details and further investigation, click here
