| Full name: KIAA1257 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 3q21.3 | ||
| Entrez ID: 57501 | HGNC ID: HGNC:29231 | Ensembl Gene: ENSG00000114656 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of KIAA1257:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KIAA1257 | 57501 | 1554852_a_at | 0.0993 | 0.7336 | |
| GSE26886 | KIAA1257 | 57501 | 1554852_a_at | 0.5964 | 0.0306 | |
| GSE45670 | KIAA1257 | 57501 | 1554852_a_at | 0.3284 | 0.1116 | |
| GSE53622 | KIAA1257 | 57501 | 916 | -0.0558 | 0.7653 | |
| GSE53624 | KIAA1257 | 57501 | 916 | 0.6876 | 0.0000 | |
| GSE63941 | KIAA1257 | 57501 | 1554852_a_at | -0.1103 | 0.8087 | |
| GSE77861 | KIAA1257 | 57501 | 1554852_a_at | 0.1129 | 0.1504 | |
| GSE97050 | KIAA1257 | 57501 | A_32_P163739 | -0.0951 | 0.7255 | |
| SRP007169 | KIAA1257 | 57501 | RNAseq | 1.6781 | 0.0111 | |
| SRP064894 | KIAA1257 | 57501 | RNAseq | 0.3627 | 0.1555 | |
| SRP133303 | KIAA1257 | 57501 | RNAseq | 0.1916 | 0.3804 | |
| SRP159526 | KIAA1257 | 57501 | RNAseq | 1.4016 | 0.0121 | |
| SRP193095 | KIAA1257 | 57501 | RNAseq | 0.2524 | 0.0555 | |
| SRP219564 | KIAA1257 | 57501 | RNAseq | -0.0471 | 0.9120 | |
| TCGA | KIAA1257 | 57501 | RNAseq | 0.1968 | 0.5708 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by KIAA1257 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KIAA1257:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KIAA1257 | 57501 | 17 | 0 | 13 | |
| GSE20123 | KIAA1257 | 57501 | 17 | 0 | 13 | |
| GSE43470 | KIAA1257 | 57501 | 19 | 0 | 24 | |
| GSE46452 | KIAA1257 | 57501 | 14 | 5 | 40 | |
| GSE47630 | KIAA1257 | 57501 | 18 | 3 | 19 | |
| GSE54993 | KIAA1257 | 57501 | 2 | 7 | 61 | |
| GSE54994 | KIAA1257 | 57501 | 31 | 3 | 19 | |
| GSE60625 | KIAA1257 | 57501 | 0 | 6 | 5 | |
| GSE74703 | KIAA1257 | 57501 | 17 | 0 | 19 | |
| GSE74704 | KIAA1257 | 57501 | 13 | 0 | 7 | |
| TCGA | KIAA1257 | 57501 | 58 | 5 | 33 |
Total number of gains: 206; Total number of losses: 29; Total Number of normals: 253.
Somatic mutations of KIAA1257:
Generating mutation plots.
Highly correlated genes for KIAA1257:
Showing top 20/250 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KIAA1257 | RNF130 | 0.772266 | 3 | 0 | 3 |
| KIAA1257 | RPTOR | 0.756367 | 3 | 0 | 3 |
| KIAA1257 | CLASRP | 0.754294 | 3 | 0 | 3 |
| KIAA1257 | CORO2B | 0.753546 | 3 | 0 | 3 |
| KIAA1257 | PKNOX1 | 0.75204 | 3 | 0 | 3 |
| KIAA1257 | NPNT | 0.75034 | 3 | 0 | 3 |
| KIAA1257 | FBXO21 | 0.734206 | 3 | 0 | 3 |
| KIAA1257 | TPRA1 | 0.734134 | 3 | 0 | 3 |
| KIAA1257 | CSPP1 | 0.730809 | 3 | 0 | 3 |
| KIAA1257 | MUS81 | 0.728127 | 3 | 0 | 3 |
| KIAA1257 | COA5 | 0.726906 | 3 | 0 | 3 |
| KIAA1257 | CDKN2D | 0.724411 | 3 | 0 | 3 |
| KIAA1257 | REV1 | 0.721483 | 3 | 0 | 3 |
| KIAA1257 | NAB2 | 0.721297 | 3 | 0 | 3 |
| KIAA1257 | PTGES2 | 0.720864 | 3 | 0 | 3 |
| KIAA1257 | NPLOC4 | 0.718857 | 3 | 0 | 3 |
| KIAA1257 | DEPDC5 | 0.718346 | 3 | 0 | 3 |
| KIAA1257 | FAM13A | 0.716147 | 3 | 0 | 3 |
| KIAA1257 | HAGH | 0.712105 | 3 | 0 | 3 |
| KIAA1257 | ZNF609 | 0.711057 | 3 | 0 | 3 |
For details and further investigation, click here
