| Full name: family with sequence similarity 133 member B | Alias Symbol: MGC40405 | ||
| Type: protein-coding gene | Cytoband: 7q21.2 | ||
| Entrez ID: 257415 | HGNC ID: HGNC:28629 | Ensembl Gene: ENSG00000234545 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of FAM133B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | FAM133B | 257415 | 13994 | 0.2581 | 0.0000 | |
| GSE53624 | FAM133B | 257415 | 13994 | 0.2860 | 0.0000 | |
| GSE97050 | FAM133B | 257415 | A_24_P247536 | -0.2343 | 0.4361 | |
| SRP007169 | FAM133B | 257415 | RNAseq | 0.1661 | 0.6487 | |
| SRP008496 | FAM133B | 257415 | RNAseq | 0.7791 | 0.0421 | |
| SRP064894 | FAM133B | 257415 | RNAseq | 0.2761 | 0.0695 | |
| SRP133303 | FAM133B | 257415 | RNAseq | 0.5046 | 0.0010 | |
| SRP159526 | FAM133B | 257415 | RNAseq | 0.1931 | 0.3752 | |
| SRP193095 | FAM133B | 257415 | RNAseq | 0.3013 | 0.0538 | |
| SRP219564 | FAM133B | 257415 | RNAseq | 0.3218 | 0.3678 | |
| TCGA | FAM133B | 257415 | RNAseq | 0.1133 | 0.2741 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FAM133B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FAM133B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAM133B | 257415 | 13 | 0 | 17 | |
| GSE20123 | FAM133B | 257415 | 13 | 0 | 17 | |
| GSE43470 | FAM133B | 257415 | 7 | 1 | 35 | |
| GSE46452 | FAM133B | 257415 | 11 | 0 | 48 | |
| GSE47630 | FAM133B | 257415 | 9 | 2 | 29 | |
| GSE54993 | FAM133B | 257415 | 1 | 9 | 60 | |
| GSE54994 | FAM133B | 257415 | 16 | 2 | 35 | |
| GSE60625 | FAM133B | 257415 | 0 | 0 | 11 | |
| GSE74703 | FAM133B | 257415 | 6 | 1 | 29 | |
| GSE74704 | FAM133B | 257415 | 9 | 0 | 11 | |
| TCGA | FAM133B | 257415 | 56 | 4 | 36 |
Total number of gains: 141; Total number of losses: 19; Total Number of normals: 328.
Somatic mutations of FAM133B:
Generating mutation plots.
Highly correlated genes for FAM133B:
Showing top 20/31 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAM133B | ESF1 | 0.727057 | 3 | 0 | 3 |
| FAM133B | CSPP1 | 0.713042 | 3 | 0 | 3 |
| FAM133B | SRSF11 | 0.711551 | 3 | 0 | 3 |
| FAM133B | WSB1 | 0.708064 | 3 | 0 | 3 |
| FAM133B | POU2F1 | 0.704981 | 3 | 0 | 3 |
| FAM133B | PILRA | 0.704793 | 4 | 0 | 4 |
| FAM133B | GATAD1 | 0.699645 | 3 | 0 | 3 |
| FAM133B | VAX2 | 0.699631 | 3 | 0 | 3 |
| FAM133B | TAS2R19 | 0.697356 | 3 | 0 | 3 |
| FAM133B | ZNF594 | 0.692289 | 3 | 0 | 3 |
| FAM133B | ANKRD36B | 0.687656 | 3 | 0 | 3 |
| FAM133B | ACAD11 | 0.685547 | 3 | 0 | 3 |
| FAM133B | PLXNA4 | 0.669334 | 3 | 0 | 3 |
| FAM133B | TIGD1 | 0.661198 | 4 | 0 | 3 |
| FAM133B | THOC2 | 0.656418 | 4 | 0 | 3 |
| FAM133B | SPDYE3 | 0.645829 | 3 | 0 | 3 |
| FAM133B | RBM39 | 0.639375 | 4 | 0 | 3 |
| FAM133B | TAS2R50 | 0.635186 | 3 | 0 | 3 |
| FAM133B | TAS2R43 | 0.632674 | 4 | 0 | 3 |
| FAM133B | ZNF318 | 0.632405 | 3 | 0 | 3 |
For details and further investigation, click here
