| Full name: elaC ribonuclease Z 2 | Alias Symbol: FLJ10530|HPC2 | ||
| Type: protein-coding gene | Cytoband: 17p12 | ||
| Entrez ID: 60528 | HGNC ID: HGNC:14198 | Ensembl Gene: ENSG00000006744 | OMIM ID: 605367 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of ELAC2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ELAC2 | 60528 | 201767_s_at | 0.3123 | 0.3581 | |
| GSE20347 | ELAC2 | 60528 | 201767_s_at | 0.1821 | 0.2601 | |
| GSE23400 | ELAC2 | 60528 | 201767_s_at | 0.2505 | 0.0000 | |
| GSE26886 | ELAC2 | 60528 | 201767_s_at | 0.7112 | 0.0001 | |
| GSE29001 | ELAC2 | 60528 | 201767_s_at | 0.1965 | 0.3492 | |
| GSE38129 | ELAC2 | 60528 | 201767_s_at | 0.2297 | 0.0486 | |
| GSE45670 | ELAC2 | 60528 | 201767_s_at | 0.2876 | 0.0159 | |
| GSE53622 | ELAC2 | 60528 | 5649 | -0.1031 | 0.1929 | |
| GSE53624 | ELAC2 | 60528 | 5649 | 0.2532 | 0.0000 | |
| GSE63941 | ELAC2 | 60528 | 201767_s_at | 0.1512 | 0.7605 | |
| GSE77861 | ELAC2 | 60528 | 201767_s_at | 0.1072 | 0.3999 | |
| GSE97050 | ELAC2 | 60528 | A_33_P3373541 | 0.0663 | 0.8432 | |
| SRP007169 | ELAC2 | 60528 | RNAseq | 0.4471 | 0.2011 | |
| SRP008496 | ELAC2 | 60528 | RNAseq | 0.4931 | 0.0375 | |
| SRP064894 | ELAC2 | 60528 | RNAseq | 0.6682 | 0.0027 | |
| SRP133303 | ELAC2 | 60528 | RNAseq | -0.0606 | 0.6553 | |
| SRP159526 | ELAC2 | 60528 | RNAseq | -0.0419 | 0.8802 | |
| SRP193095 | ELAC2 | 60528 | RNAseq | -0.0054 | 0.9540 | |
| SRP219564 | ELAC2 | 60528 | RNAseq | 0.4554 | 0.3199 | |
| TCGA | ELAC2 | 60528 | RNAseq | -0.0168 | 0.7122 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ELAC2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ELAC2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ELAC2 | 60528 | 3 | 4 | 23 | |
| GSE20123 | ELAC2 | 60528 | 3 | 5 | 22 | |
| GSE43470 | ELAC2 | 60528 | 3 | 5 | 35 | |
| GSE46452 | ELAC2 | 60528 | 34 | 1 | 24 | |
| GSE47630 | ELAC2 | 60528 | 7 | 1 | 32 | |
| GSE54993 | ELAC2 | 60528 | 3 | 2 | 65 | |
| GSE54994 | ELAC2 | 60528 | 6 | 6 | 41 | |
| GSE60625 | ELAC2 | 60528 | 4 | 0 | 7 | |
| GSE74703 | ELAC2 | 60528 | 3 | 4 | 29 | |
| GSE74704 | ELAC2 | 60528 | 2 | 2 | 16 | |
| TCGA | ELAC2 | 60528 | 17 | 22 | 57 |
Total number of gains: 85; Total number of losses: 52; Total Number of normals: 351.
Somatic mutations of ELAC2:
Generating mutation plots.
Highly correlated genes for ELAC2:
Showing top 20/1030 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ELAC2 | ANKRD17 | 0.792775 | 3 | 0 | 3 |
| ELAC2 | CEP350 | 0.783603 | 3 | 0 | 3 |
| ELAC2 | RPL7L1 | 0.776538 | 4 | 0 | 4 |
| ELAC2 | DZIP1L | 0.775026 | 3 | 0 | 3 |
| ELAC2 | ZSCAN12 | 0.771853 | 3 | 0 | 3 |
| ELAC2 | COMMD5 | 0.77173 | 3 | 0 | 3 |
| ELAC2 | KRTCAP2 | 0.762289 | 4 | 0 | 4 |
| ELAC2 | NPHP3 | 0.753967 | 3 | 0 | 3 |
| ELAC2 | THEM4 | 0.752898 | 3 | 0 | 3 |
| ELAC2 | DDX55 | 0.752607 | 4 | 0 | 4 |
| ELAC2 | BPNT1 | 0.745846 | 3 | 0 | 3 |
| ELAC2 | PPP1R35 | 0.743854 | 3 | 0 | 3 |
| ELAC2 | SURF6 | 0.737988 | 5 | 0 | 4 |
| ELAC2 | CSPP1 | 0.732773 | 4 | 0 | 4 |
| ELAC2 | GUSB | 0.732608 | 3 | 0 | 3 |
| ELAC2 | ZMYND19 | 0.727013 | 4 | 0 | 3 |
| ELAC2 | RIOK1 | 0.725532 | 5 | 0 | 5 |
| ELAC2 | NOP58 | 0.720582 | 5 | 0 | 4 |
| ELAC2 | ALG10 | 0.720401 | 3 | 0 | 3 |
| ELAC2 | SPATS2 | 0.720336 | 4 | 0 | 4 |
For details and further investigation, click here
