| Full name: glutamate rich WD repeat containing 1 | Alias Symbol: WDR28|GRWD|RRB1 | ||
| Type: protein-coding gene | Cytoband: 19q13.33 | ||
| Entrez ID: 83743 | HGNC ID: HGNC:21270 | Ensembl Gene: ENSG00000105447 | OMIM ID: 610597 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of GRWD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GRWD1 | 83743 | 221549_at | 0.6673 | 0.0757 | |
| GSE20347 | GRWD1 | 83743 | 221549_at | 0.2319 | 0.0343 | |
| GSE23400 | GRWD1 | 83743 | 221549_at | 0.3251 | 0.0000 | |
| GSE26886 | GRWD1 | 83743 | 221549_at | 0.3113 | 0.0144 | |
| GSE29001 | GRWD1 | 83743 | 221549_at | -0.0324 | 0.9000 | |
| GSE38129 | GRWD1 | 83743 | 221549_at | 0.3645 | 0.0000 | |
| GSE45670 | GRWD1 | 83743 | 221549_at | 0.2832 | 0.0005 | |
| GSE53622 | GRWD1 | 83743 | 26572 | 0.1788 | 0.0434 | |
| GSE53624 | GRWD1 | 83743 | 26572 | 0.4465 | 0.0000 | |
| GSE63941 | GRWD1 | 83743 | 221549_at | 0.1160 | 0.6974 | |
| GSE77861 | GRWD1 | 83743 | 221549_at | 0.1321 | 0.3191 | |
| GSE97050 | GRWD1 | 83743 | A_23_P142154 | 0.1940 | 0.4412 | |
| SRP007169 | GRWD1 | 83743 | RNAseq | 0.5643 | 0.1751 | |
| SRP008496 | GRWD1 | 83743 | RNAseq | 0.2766 | 0.3349 | |
| SRP064894 | GRWD1 | 83743 | RNAseq | 0.5624 | 0.0259 | |
| SRP133303 | GRWD1 | 83743 | RNAseq | 0.5770 | 0.0067 | |
| SRP159526 | GRWD1 | 83743 | RNAseq | 0.4274 | 0.0869 | |
| SRP193095 | GRWD1 | 83743 | RNAseq | 0.3816 | 0.0000 | |
| SRP219564 | GRWD1 | 83743 | RNAseq | 0.4575 | 0.1655 | |
| TCGA | GRWD1 | 83743 | RNAseq | 0.0849 | 0.1044 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GRWD1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GRWD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GRWD1 | 83743 | 4 | 4 | 22 | |
| GSE20123 | GRWD1 | 83743 | 4 | 3 | 23 | |
| GSE43470 | GRWD1 | 83743 | 4 | 11 | 28 | |
| GSE46452 | GRWD1 | 83743 | 45 | 1 | 13 | |
| GSE47630 | GRWD1 | 83743 | 9 | 6 | 25 | |
| GSE54993 | GRWD1 | 83743 | 17 | 4 | 49 | |
| GSE54994 | GRWD1 | 83743 | 4 | 14 | 35 | |
| GSE60625 | GRWD1 | 83743 | 9 | 0 | 2 | |
| GSE74703 | GRWD1 | 83743 | 4 | 7 | 25 | |
| GSE74704 | GRWD1 | 83743 | 4 | 1 | 15 | |
| TCGA | GRWD1 | 83743 | 15 | 18 | 63 |
Total number of gains: 119; Total number of losses: 69; Total Number of normals: 300.
Somatic mutations of GRWD1:
Generating mutation plots.
Highly correlated genes for GRWD1:
Showing top 20/1103 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GRWD1 | FAM90A1 | 0.810338 | 3 | 0 | 3 |
| GRWD1 | SSBP4 | 0.798918 | 3 | 0 | 3 |
| GRWD1 | RBM15B | 0.792104 | 3 | 0 | 3 |
| GRWD1 | KTI12 | 0.783007 | 3 | 0 | 3 |
| GRWD1 | PRR12 | 0.777654 | 3 | 0 | 3 |
| GRWD1 | ARHGEF11 | 0.775123 | 3 | 0 | 3 |
| GRWD1 | PHC2 | 0.774075 | 3 | 0 | 3 |
| GRWD1 | MADD | 0.773756 | 5 | 0 | 5 |
| GRWD1 | CRCP | 0.765149 | 3 | 0 | 3 |
| GRWD1 | PPP1R9B | 0.755721 | 3 | 0 | 3 |
| GRWD1 | TMEM11 | 0.754646 | 4 | 0 | 4 |
| GRWD1 | COMMD5 | 0.753746 | 4 | 0 | 4 |
| GRWD1 | ZBTB22 | 0.753039 | 3 | 0 | 3 |
| GRWD1 | CCDC15 | 0.750439 | 4 | 0 | 4 |
| GRWD1 | UBR4 | 0.750241 | 3 | 0 | 3 |
| GRWD1 | CSPP1 | 0.743845 | 4 | 0 | 3 |
| GRWD1 | ZNF628 | 0.739313 | 5 | 0 | 5 |
| GRWD1 | LEMD2 | 0.735066 | 4 | 0 | 3 |
| GRWD1 | SCAF1 | 0.733973 | 3 | 0 | 3 |
| GRWD1 | SAMM50 | 0.729132 | 3 | 0 | 3 |
For details and further investigation, click here
