| Full name: CWC15 spliceosome associated protein homolog | Alias Symbol: C11orf5|HSPC148|Cwf15|AD002 | ||
| Type: protein-coding gene | Cytoband: 11q21 | ||
| Entrez ID: 51503 | HGNC ID: HGNC:26939 | Ensembl Gene: ENSG00000150316 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of CWC15:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CWC15 | 51503 | 223067_at | -0.2571 | 0.5593 | |
| GSE26886 | CWC15 | 51503 | 223067_at | 0.5374 | 0.0204 | |
| GSE45670 | CWC15 | 51503 | 223067_at | -0.0699 | 0.6391 | |
| GSE53622 | CWC15 | 51503 | 121916 | -0.0863 | 0.1083 | |
| GSE53624 | CWC15 | 51503 | 121916 | -0.0292 | 0.5417 | |
| GSE63941 | CWC15 | 51503 | 223067_at | -0.1978 | 0.6088 | |
| GSE77861 | CWC15 | 51503 | 223067_at | -0.3491 | 0.1727 | |
| GSE97050 | CWC15 | 51503 | A_23_P98218 | 0.1754 | 0.6575 | |
| SRP007169 | CWC15 | 51503 | RNAseq | -0.7703 | 0.0313 | |
| SRP008496 | CWC15 | 51503 | RNAseq | -0.6600 | 0.0005 | |
| SRP064894 | CWC15 | 51503 | RNAseq | -0.2305 | 0.2630 | |
| SRP133303 | CWC15 | 51503 | RNAseq | -0.5202 | 0.0000 | |
| SRP159526 | CWC15 | 51503 | RNAseq | -0.2308 | 0.4167 | |
| SRP193095 | CWC15 | 51503 | RNAseq | -0.9005 | 0.0000 | |
| SRP219564 | CWC15 | 51503 | RNAseq | -0.3962 | 0.1022 | |
| TCGA | CWC15 | 51503 | RNAseq | 0.0623 | 0.2960 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CWC15 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CWC15:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CWC15 | 51503 | 3 | 8 | 19 | |
| GSE20123 | CWC15 | 51503 | 3 | 8 | 19 | |
| GSE43470 | CWC15 | 51503 | 2 | 5 | 36 | |
| GSE46452 | CWC15 | 51503 | 5 | 24 | 30 | |
| GSE47630 | CWC15 | 51503 | 2 | 19 | 19 | |
| GSE54993 | CWC15 | 51503 | 8 | 2 | 60 | |
| GSE54994 | CWC15 | 51503 | 7 | 18 | 28 | |
| GSE60625 | CWC15 | 51503 | 0 | 3 | 8 | |
| GSE74703 | CWC15 | 51503 | 1 | 4 | 31 | |
| GSE74704 | CWC15 | 51503 | 3 | 4 | 13 | |
| TCGA | CWC15 | 51503 | 11 | 43 | 42 |
Total number of gains: 45; Total number of losses: 138; Total Number of normals: 305.
Somatic mutations of CWC15:
Generating mutation plots.
Highly correlated genes for CWC15:
Showing top 20/116 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CWC15 | SACM1L | 0.747515 | 3 | 0 | 3 |
| CWC15 | ZNF83 | 0.745807 | 3 | 0 | 3 |
| CWC15 | THOC2 | 0.734297 | 4 | 0 | 4 |
| CWC15 | USP4 | 0.733527 | 3 | 0 | 3 |
| CWC15 | ZNF273 | 0.732701 | 3 | 0 | 3 |
| CWC15 | NDUFA6 | 0.728466 | 3 | 0 | 3 |
| CWC15 | ZNF432 | 0.716262 | 4 | 0 | 4 |
| CWC15 | MRPS22 | 0.709565 | 3 | 0 | 3 |
| CWC15 | ZNF529 | 0.698284 | 3 | 0 | 3 |
| CWC15 | RPL14 | 0.697611 | 3 | 0 | 3 |
| CWC15 | MRPL1 | 0.696897 | 3 | 0 | 3 |
| CWC15 | EPB41L5 | 0.692778 | 3 | 0 | 3 |
| CWC15 | HMGCS1 | 0.691078 | 3 | 0 | 3 |
| CWC15 | TMA7 | 0.688298 | 3 | 0 | 3 |
| CWC15 | EDF1 | 0.682046 | 4 | 0 | 4 |
| CWC15 | HSDL2 | 0.681481 | 3 | 0 | 3 |
| CWC15 | ZNF195 | 0.67722 | 3 | 0 | 3 |
| CWC15 | EIF5B | 0.673856 | 3 | 0 | 3 |
| CWC15 | SRSF1 | 0.67276 | 3 | 0 | 3 |
| CWC15 | CWC27 | 0.672639 | 4 | 0 | 4 |
For details and further investigation, click here
