| Full name: NADH:ubiquinone oxidoreductase subunit A6 | Alias Symbol: B14|LYRM6|CI-B14|NADHB14 | ||
| Type: protein-coding gene | Cytoband: 22q13.2 | ||
| Entrez ID: 4700 | HGNC ID: HGNC:7690 | Ensembl Gene: ENSG00000184983 | OMIM ID: 602138 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of NDUFA6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NDUFA6 | 4700 | 202001_s_at | -0.3459 | 0.4015 | |
| GSE20347 | NDUFA6 | 4700 | 202001_s_at | -0.2078 | 0.1514 | |
| GSE23400 | NDUFA6 | 4700 | 202001_s_at | -0.1521 | 0.0614 | |
| GSE26886 | NDUFA6 | 4700 | 202001_s_at | 0.6893 | 0.0005 | |
| GSE29001 | NDUFA6 | 4700 | 202001_s_at | -0.3411 | 0.1330 | |
| GSE38129 | NDUFA6 | 4700 | 202001_s_at | -0.1748 | 0.1859 | |
| GSE45670 | NDUFA6 | 4700 | 202001_s_at | -0.1316 | 0.4578 | |
| GSE53622 | NDUFA6 | 4700 | 81127 | -0.0968 | 0.1015 | |
| GSE53624 | NDUFA6 | 4700 | 81127 | 0.0891 | 0.1889 | |
| GSE63941 | NDUFA6 | 4700 | 202001_s_at | 0.5165 | 0.2436 | |
| GSE77861 | NDUFA6 | 4700 | 202001_s_at | -0.1210 | 0.7303 | |
| GSE97050 | NDUFA6 | 4700 | A_24_P23245 | -0.1520 | 0.5020 | |
| SRP007169 | NDUFA6 | 4700 | RNAseq | -0.7788 | 0.0139 | |
| SRP008496 | NDUFA6 | 4700 | RNAseq | -0.7675 | 0.0000 | |
| SRP064894 | NDUFA6 | 4700 | RNAseq | -0.0061 | 0.9814 | |
| SRP133303 | NDUFA6 | 4700 | RNAseq | 0.1790 | 0.3446 | |
| SRP159526 | NDUFA6 | 4700 | RNAseq | 0.0356 | 0.8561 | |
| SRP193095 | NDUFA6 | 4700 | RNAseq | -0.6092 | 0.0001 | |
| SRP219564 | NDUFA6 | 4700 | RNAseq | -0.3418 | 0.3197 | |
| TCGA | NDUFA6 | 4700 | RNAseq | -0.0522 | 0.3254 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NDUFA6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NDUFA6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NDUFA6 | 4700 | 6 | 6 | 18 | |
| GSE20123 | NDUFA6 | 4700 | 6 | 5 | 19 | |
| GSE43470 | NDUFA6 | 4700 | 5 | 6 | 32 | |
| GSE46452 | NDUFA6 | 4700 | 31 | 2 | 26 | |
| GSE47630 | NDUFA6 | 4700 | 9 | 4 | 27 | |
| GSE54993 | NDUFA6 | 4700 | 3 | 6 | 61 | |
| GSE54994 | NDUFA6 | 4700 | 11 | 8 | 34 | |
| GSE60625 | NDUFA6 | 4700 | 5 | 0 | 6 | |
| GSE74703 | NDUFA6 | 4700 | 5 | 4 | 27 | |
| GSE74704 | NDUFA6 | 4700 | 3 | 3 | 14 | |
| TCGA | NDUFA6 | 4700 | 27 | 14 | 55 |
Total number of gains: 111; Total number of losses: 58; Total Number of normals: 319.
Somatic mutations of NDUFA6:
Generating mutation plots.
Highly correlated genes for NDUFA6:
Showing top 20/122 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NDUFA6 | CRIPT | 0.75202 | 3 | 0 | 3 |
| NDUFA6 | CWC15 | 0.728466 | 3 | 0 | 3 |
| NDUFA6 | DNAJC18 | 0.713185 | 3 | 0 | 3 |
| NDUFA6 | SREK1IP1 | 0.699013 | 3 | 0 | 3 |
| NDUFA6 | ZBTB8A | 0.679595 | 3 | 0 | 3 |
| NDUFA6 | PRR34-AS1 | 0.677519 | 4 | 0 | 4 |
| NDUFA6 | HERPUD2 | 0.66986 | 3 | 0 | 3 |
| NDUFA6 | TUFT1 | 0.65425 | 3 | 0 | 3 |
| NDUFA6 | ZNF689 | 0.650169 | 3 | 0 | 3 |
| NDUFA6 | FNDC8 | 0.644467 | 3 | 0 | 3 |
| NDUFA6 | NQO1 | 0.643513 | 4 | 0 | 4 |
| NDUFA6 | SRP19 | 0.641654 | 3 | 0 | 3 |
| NDUFA6 | EMC7 | 0.635245 | 3 | 0 | 3 |
| NDUFA6 | ADAMTS10 | 0.633946 | 3 | 0 | 3 |
| NDUFA6 | EVC2 | 0.621756 | 3 | 0 | 3 |
| NDUFA6 | NCAPH2 | 0.621658 | 4 | 0 | 3 |
| NDUFA6 | MAPK9 | 0.619944 | 4 | 0 | 3 |
| NDUFA6 | DECR2 | 0.619362 | 3 | 0 | 3 |
| NDUFA6 | NDUFB5 | 0.617266 | 4 | 0 | 3 |
| NDUFA6 | ZNF480 | 0.615376 | 3 | 0 | 3 |
For details and further investigation, click here
