| Full name: hydroxysteroid dehydrogenase like 2 | Alias Symbol: SDR13C1 | ||
| Type: protein-coding gene | Cytoband: 9q32 | ||
| Entrez ID: 84263 | HGNC ID: HGNC:18572 | Ensembl Gene: ENSG00000119471 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of HSDL2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HSDL2 | 84263 | 209513_s_at | -0.7543 | 0.0357 | |
| GSE20347 | HSDL2 | 84263 | 209513_s_at | -1.4635 | 0.0000 | |
| GSE23400 | HSDL2 | 84263 | 209513_s_at | -0.4975 | 0.0000 | |
| GSE26886 | HSDL2 | 84263 | 209513_s_at | -0.8151 | 0.0003 | |
| GSE29001 | HSDL2 | 84263 | 209513_s_at | -0.9638 | 0.0236 | |
| GSE38129 | HSDL2 | 84263 | 209513_s_at | -1.3365 | 0.0000 | |
| GSE45670 | HSDL2 | 84263 | 209513_s_at | -0.7408 | 0.0007 | |
| GSE53622 | HSDL2 | 84263 | 3775 | -0.9109 | 0.0000 | |
| GSE53624 | HSDL2 | 84263 | 3775 | -0.7558 | 0.0000 | |
| GSE63941 | HSDL2 | 84263 | 209513_s_at | -0.9119 | 0.2283 | |
| GSE77861 | HSDL2 | 84263 | 209513_s_at | -0.8179 | 0.0571 | |
| GSE97050 | HSDL2 | 84263 | A_23_P169197 | -0.6989 | 0.0750 | |
| SRP007169 | HSDL2 | 84263 | RNAseq | -1.3984 | 0.0035 | |
| SRP008496 | HSDL2 | 84263 | RNAseq | -1.5487 | 0.0000 | |
| SRP064894 | HSDL2 | 84263 | RNAseq | -0.6651 | 0.0000 | |
| SRP133303 | HSDL2 | 84263 | RNAseq | -0.7366 | 0.0004 | |
| SRP159526 | HSDL2 | 84263 | RNAseq | -1.3490 | 0.0000 | |
| SRP193095 | HSDL2 | 84263 | RNAseq | -1.0278 | 0.0000 | |
| SRP219564 | HSDL2 | 84263 | RNAseq | -1.4285 | 0.0000 | |
| TCGA | HSDL2 | 84263 | RNAseq | -0.2696 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 7.
Survival by HSDL2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HSDL2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HSDL2 | 84263 | 5 | 10 | 15 | |
| GSE20123 | HSDL2 | 84263 | 5 | 10 | 15 | |
| GSE43470 | HSDL2 | 84263 | 4 | 3 | 36 | |
| GSE46452 | HSDL2 | 84263 | 6 | 13 | 40 | |
| GSE47630 | HSDL2 | 84263 | 3 | 16 | 21 | |
| GSE54993 | HSDL2 | 84263 | 3 | 3 | 64 | |
| GSE54994 | HSDL2 | 84263 | 9 | 10 | 34 | |
| GSE60625 | HSDL2 | 84263 | 0 | 0 | 11 | |
| GSE74703 | HSDL2 | 84263 | 4 | 3 | 29 | |
| GSE74704 | HSDL2 | 84263 | 2 | 8 | 10 | |
| TCGA | HSDL2 | 84263 | 26 | 22 | 48 |
Total number of gains: 67; Total number of losses: 98; Total Number of normals: 323.
Somatic mutations of HSDL2:
Generating mutation plots.
Highly correlated genes for HSDL2:
Showing top 20/1526 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HSDL2 | GPD1L | 0.756333 | 11 | 0 | 11 |
| HSDL2 | FBXW5 | 0.750608 | 5 | 0 | 5 |
| HSDL2 | HDHD2 | 0.74695 | 5 | 0 | 5 |
| HSDL2 | CLEC3B | 0.746283 | 3 | 0 | 3 |
| HSDL2 | DENND1B | 0.73508 | 3 | 0 | 3 |
| HSDL2 | CYTH2 | 0.733769 | 3 | 0 | 3 |
| HSDL2 | HIGD1A | 0.73241 | 11 | 0 | 11 |
| HSDL2 | ALDOA | 0.731559 | 3 | 0 | 3 |
| HSDL2 | LRRFIP2 | 0.727081 | 11 | 0 | 11 |
| HSDL2 | MRPS36 | 0.726719 | 7 | 0 | 7 |
| HSDL2 | CYSRT1 | 0.722856 | 6 | 0 | 6 |
| HSDL2 | ACOT12 | 0.718853 | 3 | 0 | 3 |
| HSDL2 | EIF4E3 | 0.716836 | 7 | 0 | 7 |
| HSDL2 | FAM104B | 0.712902 | 3 | 0 | 3 |
| HSDL2 | SMARCC2 | 0.712217 | 3 | 0 | 3 |
| HSDL2 | KAT2B | 0.710003 | 12 | 0 | 11 |
| HSDL2 | NFIA | 0.709401 | 7 | 0 | 6 |
| HSDL2 | KCTD6 | 0.708096 | 7 | 0 | 7 |
| HSDL2 | RSPH3 | 0.7079 | 4 | 0 | 4 |
| HSDL2 | NUCB2 | 0.707241 | 11 | 0 | 11 |
For details and further investigation, click here
