| Full name: SAC1 like phosphatidylinositide phosphatase | Alias Symbol: SAC1|KIAA0851 | ||
| Type: protein-coding gene | Cytoband: 3p21.31 | ||
| Entrez ID: 22908 | HGNC ID: HGNC:17059 | Ensembl Gene: ENSG00000211456 | OMIM ID: 606569 |
| Drug and gene relationship at DGIdb | |||
Expression of SACM1L:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SACM1L | 22908 | 202797_at | -0.2799 | 0.3178 | |
| GSE20347 | SACM1L | 22908 | 202797_at | -0.8274 | 0.0000 | |
| GSE23400 | SACM1L | 22908 | 202797_at | -0.1716 | 0.0400 | |
| GSE26886 | SACM1L | 22908 | 202797_at | -0.7498 | 0.0041 | |
| GSE29001 | SACM1L | 22908 | 202797_at | -0.6394 | 0.0383 | |
| GSE38129 | SACM1L | 22908 | 202797_at | -0.7475 | 0.0000 | |
| GSE45670 | SACM1L | 22908 | 202797_at | -0.2310 | 0.0853 | |
| GSE53622 | SACM1L | 22908 | 85826 | -0.3803 | 0.0000 | |
| GSE53624 | SACM1L | 22908 | 85826 | -0.6196 | 0.0000 | |
| GSE63941 | SACM1L | 22908 | 202797_at | -1.1211 | 0.0022 | |
| GSE77861 | SACM1L | 22908 | 202797_at | -0.5998 | 0.0411 | |
| GSE97050 | SACM1L | 22908 | A_23_P212383 | -0.1733 | 0.4581 | |
| SRP007169 | SACM1L | 22908 | RNAseq | -0.8297 | 0.0139 | |
| SRP008496 | SACM1L | 22908 | RNAseq | -0.7685 | 0.0000 | |
| SRP064894 | SACM1L | 22908 | RNAseq | -0.4030 | 0.0343 | |
| SRP133303 | SACM1L | 22908 | RNAseq | -0.2965 | 0.0162 | |
| SRP159526 | SACM1L | 22908 | RNAseq | -0.5477 | 0.0120 | |
| SRP193095 | SACM1L | 22908 | RNAseq | -0.6230 | 0.0000 | |
| SRP219564 | SACM1L | 22908 | RNAseq | -0.4639 | 0.0331 | |
| TCGA | SACM1L | 22908 | RNAseq | -0.2955 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by SACM1L expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SACM1L:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SACM1L | 22908 | 0 | 17 | 13 | |
| GSE20123 | SACM1L | 22908 | 0 | 18 | 12 | |
| GSE43470 | SACM1L | 22908 | 0 | 20 | 23 | |
| GSE46452 | SACM1L | 22908 | 2 | 17 | 40 | |
| GSE47630 | SACM1L | 22908 | 1 | 24 | 15 | |
| GSE54993 | SACM1L | 22908 | 7 | 2 | 61 | |
| GSE54994 | SACM1L | 22908 | 0 | 36 | 17 | |
| GSE60625 | SACM1L | 22908 | 5 | 0 | 6 | |
| GSE74703 | SACM1L | 22908 | 0 | 15 | 21 | |
| GSE74704 | SACM1L | 22908 | 0 | 12 | 8 | |
| TCGA | SACM1L | 22908 | 1 | 75 | 20 |
Total number of gains: 16; Total number of losses: 236; Total Number of normals: 236.
Somatic mutations of SACM1L:
Generating mutation plots.
Highly correlated genes for SACM1L:
Showing top 20/1499 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SACM1L | ZNF394 | 0.79373 | 3 | 0 | 3 |
| SACM1L | NAA35 | 0.776482 | 4 | 0 | 3 |
| SACM1L | TMEM50A | 0.772129 | 3 | 0 | 3 |
| SACM1L | GOLGA4 | 0.770127 | 9 | 0 | 9 |
| SACM1L | RSAD1 | 0.762857 | 3 | 0 | 3 |
| SACM1L | NDUFAF2 | 0.762562 | 3 | 0 | 3 |
| SACM1L | FIBIN | 0.75317 | 3 | 0 | 3 |
| SACM1L | CWC15 | 0.747515 | 3 | 0 | 3 |
| SACM1L | SNX18 | 0.738384 | 3 | 0 | 3 |
| SACM1L | NKAPL | 0.733438 | 3 | 0 | 3 |
| SACM1L | ELMOD2 | 0.732113 | 5 | 0 | 5 |
| SACM1L | GPD2 | 0.731947 | 4 | 0 | 4 |
| SACM1L | OCRL | 0.731534 | 3 | 0 | 3 |
| SACM1L | TMEM126A | 0.729644 | 5 | 0 | 5 |
| SACM1L | SUCLG2 | 0.729247 | 13 | 0 | 12 |
| SACM1L | SLC9A6 | 0.723758 | 3 | 0 | 3 |
| SACM1L | UBE2Q2 | 0.722723 | 3 | 0 | 3 |
| SACM1L | HDHD2 | 0.722254 | 6 | 0 | 6 |
| SACM1L | TMEM167B | 0.7211 | 4 | 0 | 4 |
| SACM1L | UBA3 | 0.720641 | 12 | 0 | 11 |
For details and further investigation, click here
