| Full name: mitochondrial ribosomal protein L1 | Alias Symbol: BM022 | ||
| Type: protein-coding gene | Cytoband: 4q21.1 | ||
| Entrez ID: 65008 | HGNC ID: HGNC:14275 | Ensembl Gene: ENSG00000169288 | OMIM ID: 611821 |
Screen Evidence:
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Expression of MRPL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MRPL1 | 65008 | 223154_at | 0.1085 | 0.8663 | |
| GSE26886 | MRPL1 | 65008 | 223154_at | 0.1057 | 0.6123 | |
| GSE45670 | MRPL1 | 65008 | 223154_at | -0.0193 | 0.9324 | |
| GSE63941 | MRPL1 | 65008 | 223154_at | 0.4774 | 0.2743 | |
| GSE77861 | MRPL1 | 65008 | 223154_at | -0.3524 | 0.3653 | |
| GSE97050 | MRPL1 | 65008 | A_23_P84821 | 0.4558 | 0.1734 | |
| SRP007169 | MRPL1 | 65008 | RNAseq | -0.2967 | 0.4695 | |
| SRP008496 | MRPL1 | 65008 | RNAseq | -0.2403 | 0.3212 | |
| SRP064894 | MRPL1 | 65008 | RNAseq | -0.1833 | 0.3234 | |
| SRP133303 | MRPL1 | 65008 | RNAseq | 0.0274 | 0.8888 | |
| SRP159526 | MRPL1 | 65008 | RNAseq | -0.5480 | 0.0308 | |
| SRP193095 | MRPL1 | 65008 | RNAseq | -0.4605 | 0.0012 | |
| SRP219564 | MRPL1 | 65008 | RNAseq | -0.2557 | 0.4504 | |
| TCGA | MRPL1 | 65008 | RNAseq | -0.0081 | 0.9008 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MRPL1 expression:
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| TCGA |
Note: Click image to view full size file.
Copy number change of MRPL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MRPL1 | 65008 | 2 | 9 | 19 | |
| GSE20123 | MRPL1 | 65008 | 2 | 9 | 19 | |
| GSE43470 | MRPL1 | 65008 | 1 | 12 | 30 | |
| GSE46452 | MRPL1 | 65008 | 1 | 36 | 22 | |
| GSE47630 | MRPL1 | 65008 | 1 | 19 | 20 | |
| GSE54993 | MRPL1 | 65008 | 7 | 0 | 63 | |
| GSE54994 | MRPL1 | 65008 | 0 | 9 | 44 | |
| GSE60625 | MRPL1 | 65008 | 0 | 0 | 11 | |
| GSE74703 | MRPL1 | 65008 | 1 | 10 | 25 | |
| GSE74704 | MRPL1 | 65008 | 2 | 5 | 13 | |
| TCGA | MRPL1 | 65008 | 14 | 32 | 50 |
Total number of gains: 31; Total number of losses: 141; Total Number of normals: 316.
Somatic mutations of MRPL1:
Generating mutation plots.
Highly correlated genes for MRPL1:
Showing top 20/104 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MRPL1 | DECR1 | 0.849774 | 3 | 0 | 3 |
| MRPL1 | RBM34 | 0.804559 | 3 | 0 | 3 |
| MRPL1 | NAA15 | 0.797634 | 3 | 0 | 3 |
| MRPL1 | UTP3 | 0.795486 | 4 | 0 | 4 |
| MRPL1 | PLAA | 0.765111 | 3 | 0 | 3 |
| MRPL1 | MRPS9 | 0.760799 | 3 | 0 | 3 |
| MRPL1 | HCCS | 0.760536 | 3 | 0 | 3 |
| MRPL1 | B4GALT5 | 0.75995 | 3 | 0 | 3 |
| MRPL1 | SPIC | 0.759752 | 3 | 0 | 3 |
| MRPL1 | MRPS18A | 0.752644 | 3 | 0 | 3 |
| MRPL1 | SUB1 | 0.751119 | 3 | 0 | 3 |
| MRPL1 | NCOA2 | 0.742998 | 3 | 0 | 3 |
| MRPL1 | SDAD1 | 0.741683 | 4 | 0 | 3 |
| MRPL1 | RCHY1 | 0.741065 | 5 | 0 | 5 |
| MRPL1 | ZNF234 | 0.74071 | 3 | 0 | 3 |
| MRPL1 | NBN | 0.733744 | 3 | 0 | 3 |
| MRPL1 | PPP4R2 | 0.730877 | 3 | 0 | 3 |
| MRPL1 | TRIAP1 | 0.730002 | 4 | 0 | 3 |
| MRPL1 | KDM2A | 0.726339 | 3 | 0 | 3 |
| MRPL1 | ECHDC1 | 0.725457 | 3 | 0 | 3 |
For details and further investigation, click here
