| Full name: C-X-C motif chemokine receptor 3 | Alias Symbol: CKR-L2|CMKAR3|IP10-R|MigR|CD183 | ||
| Type: protein-coding gene | Cytoband: Xq13.1 | ||
| Entrez ID: 2833 | HGNC ID: HGNC:4540 | Ensembl Gene: ENSG00000186810 | OMIM ID: 300574 |
| Drug and gene relationship at DGIdb | |||
CXCR3 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04062 | Chemokine signaling pathway |
Expression of CXCR3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CXCR3 | 2833 | 217119_s_at | -0.1493 | 0.5621 | |
| GSE20347 | CXCR3 | 2833 | 217119_s_at | -0.2907 | 0.0020 | |
| GSE23400 | CXCR3 | 2833 | 207681_at | -0.1572 | 0.0000 | |
| GSE26886 | CXCR3 | 2833 | 217119_s_at | 0.1398 | 0.3893 | |
| GSE29001 | CXCR3 | 2833 | 207681_at | -0.1811 | 0.3552 | |
| GSE38129 | CXCR3 | 2833 | 217119_s_at | -0.3691 | 0.0003 | |
| GSE45670 | CXCR3 | 2833 | 217119_s_at | -0.2265 | 0.0090 | |
| GSE53622 | CXCR3 | 2833 | 24065 | 0.1536 | 0.0612 | |
| GSE53624 | CXCR3 | 2833 | 24065 | -0.0359 | 0.6764 | |
| GSE63941 | CXCR3 | 2833 | 217119_s_at | 0.2441 | 0.0939 | |
| GSE77861 | CXCR3 | 2833 | 217119_s_at | -0.2058 | 0.1475 | |
| GSE97050 | CXCR3 | 2833 | A_33_P3389230 | 0.5613 | 0.2690 | |
| SRP133303 | CXCR3 | 2833 | RNAseq | -0.4525 | 0.1310 | |
| SRP219564 | CXCR3 | 2833 | RNAseq | 0.7430 | 0.1543 | |
| TCGA | CXCR3 | 2833 | RNAseq | 0.0932 | 0.7655 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CXCR3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CXCR3:
No record found for this gene.
Somatic mutations of CXCR3:
Generating mutation plots.
Highly correlated genes for CXCR3:
Showing top 20/685 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CXCR3 | GPR78 | 0.736465 | 3 | 0 | 3 |
| CXCR3 | IFNK | 0.728021 | 3 | 0 | 3 |
| CXCR3 | DNAI1 | 0.689347 | 3 | 0 | 3 |
| CXCR3 | C10orf67 | 0.670533 | 3 | 0 | 3 |
| CXCR3 | FMN2 | 0.659638 | 3 | 0 | 3 |
| CXCR3 | ODF1 | 0.658254 | 3 | 0 | 3 |
| CXCR3 | RBMXL2 | 0.649832 | 3 | 0 | 3 |
| CXCR3 | DENND1C | 0.649686 | 4 | 0 | 3 |
| CXCR3 | PURB | 0.648764 | 4 | 0 | 4 |
| CXCR3 | FAM171A2 | 0.646896 | 4 | 0 | 3 |
| CXCR3 | MMEL1 | 0.64676 | 3 | 0 | 3 |
| CXCR3 | BSPRY | 0.646429 | 6 | 0 | 6 |
| CXCR3 | KIR3DS1 | 0.645059 | 4 | 0 | 3 |
| CXCR3 | ADAMTS7 | 0.645035 | 5 | 0 | 5 |
| CXCR3 | SLC4A9 | 0.644875 | 4 | 0 | 3 |
| CXCR3 | IL12A-AS1 | 0.639056 | 3 | 0 | 3 |
| CXCR3 | PRSS53 | 0.63856 | 3 | 0 | 3 |
| CXCR3 | NT5C1A | 0.637763 | 4 | 0 | 3 |
| CXCR3 | RUVBL2 | 0.636744 | 3 | 0 | 3 |
| CXCR3 | SIRT7 | 0.633187 | 6 | 0 | 5 |
For details and further investigation, click here
