RUVBL2

 

Full name: RuvB like AAA ATPase 2 Alias Symbol: RVB2|TIP48|TIP49b|Reptin52|ECP51|TIH2|INO80J|Rvb2
Type: protein-coding gene Cytoband: 19q13.33
Entrez ID: 10856 HGNC ID: HGNC:10475 Ensembl Gene: ENSG00000183207 OMIM ID: 604788
Drug and gene relationship at DGIdb

 

Expression of RUVBL2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 RUVBL2 10856 1559946_s_at 0.5557 0.1482
GSE20347 RUVBL2 10856 201459_at 0.1611 0.2242
GSE23400 RUVBL2 10856 201459_at 0.3612 0.0000
GSE26886 RUVBL2 10856 1559946_s_at 0.9449 0.0000
GSE29001 RUVBL2 10856 201459_at 0.1819 0.5009
GSE38129 RUVBL2 10856 201459_at 0.4859 0.0002
GSE45670 RUVBL2 10856 1559946_s_at 0.3746 0.0120
GSE53622 RUVBL2 10856 48621 0.3931 0.0000
GSE53624 RUVBL2 10856 38152 0.5477 0.0000
GSE63941 RUVBL2 10856 1559946_s_at 1.2193 0.0004
GSE77861 RUVBL2 10856 1559946_s_at 0.0570 0.8299
GSE97050 RUVBL2 10856 A_23_P39110 0.4409 0.1409
SRP007169 RUVBL2 10856 RNAseq 0.4161 0.1943
SRP008496 RUVBL2 10856 RNAseq 0.1104 0.6411
SRP064894 RUVBL2 10856 RNAseq 0.6831 0.0224
SRP133303 RUVBL2 10856 RNAseq 0.4486 0.0554
SRP159526 RUVBL2 10856 RNAseq 0.5583 0.0360
SRP193095 RUVBL2 10856 RNAseq 0.3419 0.0119
SRP219564 RUVBL2 10856 RNAseq 0.3853 0.2773
TCGA RUVBL2 10856 RNAseq 0.2327 0.0000

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by RUVBL2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of RUVBL2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 RUVBL2 10856 4 4 22
GSE20123 RUVBL2 10856 4 3 23
GSE43470 RUVBL2 10856 4 10 29
GSE46452 RUVBL2 10856 45 1 13
GSE47630 RUVBL2 10856 9 6 25
GSE54993 RUVBL2 10856 17 4 49
GSE54994 RUVBL2 10856 4 14 35
GSE60625 RUVBL2 10856 9 0 2
GSE74703 RUVBL2 10856 4 7 25
GSE74704 RUVBL2 10856 4 1 15
TCGA RUVBL2 10856 14 18 64

Total number of gains: 118; Total number of losses: 68; Total Number of normals: 302.  

 

Somatic mutations of RUVBL2:

 

Generating mutation plots.

 

Highly correlated genes for RUVBL2:

 

Showing top 20/1008 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
RUVBL2C19orf480.787018303
RUVBL2BOP10.739742303
RUVBL2MEX3A0.725942303
RUVBL2TRIM280.71318410010
RUVBL2PLCG10.70717303
RUVBL2POU4F10.701629303
RUVBL2POLR1A0.699435303
RUVBL2ZNF1330.698882303
RUVBL2HSPBP10.6986671109
RUVBL2TOMM400.6911821008
RUVBL2DHX370.685289606
RUVBL2GAS6-AS10.675799303
RUVBL2NCAPG0.67011807
RUVBL2PPHLN10.668009303
RUVBL2RHPN20.666289606
RUVBL2CEP890.665736403
RUVBL2PRR190.664311303
RUVBL2PTBP10.66290310010
RUVBL2ZNF5790.661344404
RUVBL2SNRPD20.66112612011

For details and further investigation, click here