| Full name: formin 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1q43 | ||
| Entrez ID: 56776 | HGNC ID: HGNC:14074 | Ensembl Gene: ENSG00000155816 | OMIM ID: 606373 |
| Drug and gene relationship at DGIdb | |||
Expression of FMN2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FMN2 | 56776 | 230946_at | -0.0821 | 0.6950 | |
| GSE26886 | FMN2 | 56776 | 230946_at | -0.0222 | 0.8992 | |
| GSE45670 | FMN2 | 56776 | 230946_at | -0.2092 | 0.0742 | |
| GSE53622 | FMN2 | 56776 | 54421 | -0.9497 | 0.0002 | |
| GSE53624 | FMN2 | 56776 | 87446 | -0.7599 | 0.0054 | |
| GSE63941 | FMN2 | 56776 | 230946_at | 0.0041 | 0.9850 | |
| GSE77861 | FMN2 | 56776 | 230946_at | -0.3302 | 0.0543 | |
| SRP133303 | FMN2 | 56776 | RNAseq | -0.0278 | 0.9666 | |
| TCGA | FMN2 | 56776 | RNAseq | -1.4903 | 0.0140 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by FMN2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FMN2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FMN2 | 56776 | 8 | 2 | 20 | |
| GSE20123 | FMN2 | 56776 | 8 | 2 | 20 | |
| GSE43470 | FMN2 | 56776 | 6 | 1 | 36 | |
| GSE46452 | FMN2 | 56776 | 4 | 2 | 53 | |
| GSE47630 | FMN2 | 56776 | 15 | 0 | 25 | |
| GSE54993 | FMN2 | 56776 | 0 | 6 | 64 | |
| GSE54994 | FMN2 | 56776 | 16 | 2 | 35 | |
| GSE60625 | FMN2 | 56776 | 0 | 0 | 11 | |
| GSE74703 | FMN2 | 56776 | 6 | 1 | 29 | |
| GSE74704 | FMN2 | 56776 | 2 | 1 | 17 | |
| TCGA | FMN2 | 56776 | 44 | 5 | 47 |
Total number of gains: 109; Total number of losses: 22; Total Number of normals: 357.
Somatic mutations of FMN2:
Generating mutation plots.
Highly correlated genes for FMN2:
Showing top 20/220 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FMN2 | NOXO1 | 0.788275 | 3 | 0 | 3 |
| FMN2 | PLEKHN1 | 0.764599 | 3 | 0 | 3 |
| FMN2 | UBASH3B | 0.748476 | 3 | 0 | 3 |
| FMN2 | CD300LG | 0.743436 | 3 | 0 | 3 |
| FMN2 | SARDH | 0.73074 | 3 | 0 | 3 |
| FMN2 | YTHDF3-AS1 | 0.729433 | 3 | 0 | 3 |
| FMN2 | EPB42 | 0.714319 | 3 | 0 | 3 |
| FMN2 | FUT7 | 0.698549 | 3 | 0 | 3 |
| FMN2 | FSHB | 0.68945 | 3 | 0 | 3 |
| FMN2 | SEMA6C | 0.684004 | 4 | 0 | 4 |
| FMN2 | MYBL1 | 0.683521 | 3 | 0 | 3 |
| FMN2 | HGFAC | 0.682494 | 3 | 0 | 3 |
| FMN2 | DLGAP2 | 0.675709 | 3 | 0 | 3 |
| FMN2 | CYP3A43 | 0.674842 | 3 | 0 | 3 |
| FMN2 | ADORA1 | 0.674405 | 3 | 0 | 3 |
| FMN2 | NOXA1 | 0.674239 | 3 | 0 | 3 |
| FMN2 | TBKBP1 | 0.674092 | 3 | 0 | 3 |
| FMN2 | ISYNA1 | 0.671411 | 3 | 0 | 3 |
| FMN2 | FAM171A2 | 0.668597 | 4 | 0 | 3 |
| FMN2 | KRT3 | 0.666537 | 4 | 0 | 4 |
For details and further investigation, click here
