| Full name: purine rich element binding protein B | Alias Symbol: PURBETA | ||
| Type: protein-coding gene | Cytoband: 7p13 | ||
| Entrez ID: 5814 | HGNC ID: HGNC:9702 | Ensembl Gene: ENSG00000146676 | OMIM ID: 608887 |
| Drug and gene relationship at DGIdb | |||
Expression of PURB:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PURB | 5814 | 228467_at | -0.0757 | 0.7655 | |
| GSE26886 | PURB | 5814 | 228467_at | 0.2146 | 0.1438 | |
| GSE45670 | PURB | 5814 | 228467_at | -0.1616 | 0.2133 | |
| GSE53622 | PURB | 5814 | 110617 | 0.0662 | 0.4061 | |
| GSE53624 | PURB | 5814 | 110308 | 0.2069 | 0.0001 | |
| GSE63941 | PURB | 5814 | 228467_at | 0.3430 | 0.0349 | |
| GSE77861 | PURB | 5814 | 228467_at | -0.1493 | 0.1411 | |
| GSE97050 | PURB | 5814 | A_23_P134517 | -0.0534 | 0.8882 | |
| SRP007169 | PURB | 5814 | RNAseq | 1.1071 | 0.0140 | |
| SRP008496 | PURB | 5814 | RNAseq | 1.0092 | 0.0001 | |
| SRP064894 | PURB | 5814 | RNAseq | 0.2237 | 0.1421 | |
| SRP133303 | PURB | 5814 | RNAseq | 0.3820 | 0.0160 | |
| SRP159526 | PURB | 5814 | RNAseq | 0.2765 | 0.1193 | |
| SRP193095 | PURB | 5814 | RNAseq | 0.2455 | 0.0443 | |
| SRP219564 | PURB | 5814 | RNAseq | -0.1492 | 0.5897 | |
| TCGA | PURB | 5814 | RNAseq | 0.0823 | 0.0944 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by PURB expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PURB:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PURB | 5814 | 13 | 0 | 17 | |
| GSE20123 | PURB | 5814 | 12 | 0 | 18 | |
| GSE43470 | PURB | 5814 | 4 | 0 | 39 | |
| GSE46452 | PURB | 5814 | 11 | 1 | 47 | |
| GSE47630 | PURB | 5814 | 8 | 1 | 31 | |
| GSE54993 | PURB | 5814 | 0 | 8 | 62 | |
| GSE54994 | PURB | 5814 | 16 | 3 | 34 | |
| GSE60625 | PURB | 5814 | 0 | 0 | 11 | |
| GSE74703 | PURB | 5814 | 4 | 0 | 32 | |
| GSE74704 | PURB | 5814 | 6 | 0 | 14 | |
| TCGA | PURB | 5814 | 50 | 7 | 39 |
Total number of gains: 124; Total number of losses: 20; Total Number of normals: 344.
Somatic mutations of PURB:
Generating mutation plots.
Highly correlated genes for PURB:
Showing top 20/104 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PURB | PYY | 0.687138 | 3 | 0 | 3 |
| PURB | KCNF1 | 0.679497 | 3 | 0 | 3 |
| PURB | GALNTL5 | 0.679409 | 3 | 0 | 3 |
| PURB | ZMYND10 | 0.668956 | 3 | 0 | 3 |
| PURB | USHBP1 | 0.666935 | 3 | 0 | 3 |
| PURB | RNF31 | 0.662532 | 3 | 0 | 3 |
| PURB | PYDC1 | 0.659136 | 3 | 0 | 3 |
| PURB | CLDN9 | 0.656825 | 3 | 0 | 3 |
| PURB | LINC00608 | 0.650872 | 3 | 0 | 3 |
| PURB | NPEPL1 | 0.649797 | 4 | 0 | 4 |
| PURB | CXCR3 | 0.648764 | 4 | 0 | 4 |
| PURB | LINC01115 | 0.629439 | 3 | 0 | 3 |
| PURB | C2CD4B | 0.628994 | 4 | 0 | 3 |
| PURB | FUT7 | 0.628234 | 5 | 0 | 3 |
| PURB | CCDC185 | 0.627694 | 3 | 0 | 3 |
| PURB | TMEM132E | 0.624835 | 3 | 0 | 3 |
| PURB | IGFN1 | 0.622204 | 3 | 0 | 3 |
| PURB | LINC00628 | 0.620338 | 3 | 0 | 3 |
| PURB | MYL10 | 0.613051 | 4 | 0 | 3 |
| PURB | IGH | 0.60915 | 3 | 0 | 3 |
For details and further investigation, click here
